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Lysine (K)-Specific Demethylase 1A (KDM1A) ELISA Kits

KDM1A encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. Additionally we are shipping Lysine (K)-Specific Demethylase 1A Antibodies (185) and Lysine (K)-Specific Demethylase 1A Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
KDM1A 23028 O60341
KDM1A 99982 Q6ZQ88
Anti-Rat KDM1A KDM1A 500569  
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Top Lysine (K)-Specific Demethylase 1A ELISA Kits at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 0.312-20 ng/mL 96 Tests Log in to see 11 to 13 Days
$875.60
Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
Details

More ELISA Kits for Lysine (K)-Specific Demethylase 1A Interaction Partners

Human Lysine (K)-Specific Demethylase 1A (KDM1A) interaction partners

  1. Data show that lysine-specific demethylase (show MBD2 ELISA Kits) 1 (LSD1) is a drug target for mixed lineage leukemia (MLL (show MLL ELISA Kits))-rearranged leukemia, and LSD1 inhibitors are potential therapeutics for the malignancy.

  2. Results show that LSD1 is upregulated in human prostate cancer and plays an oncogenic role.

  3. Authors found positive correlations between LSD1 expression and other proteins: epithelial-mesenchymal transition markers, C-myc (show MYC ELISA Kits) and cyclin (show PCNA ELISA Kits)-related proteins. Inhibiting LSD1 expression in vitro impaired the proliferation and invasiveness of GBC cells and also downregulated c-myc (show MYC ELISA Kits) expression and consequently inhibited GBC cell proliferation.

  4. These results highlight a novel mechanism regulating LSD1 expression and identify LSD1 as a promising therapeutic target for treating metastatic ovarian cancer driven by EGF (show EGF ELISA Kits) signaling.

  5. these data suggest that KDM1A likely contains a histone H3 (show HIST3H3 ELISA Kits) secondary specificity element on the enzyme surface that contributes significantly to its recognition of substrates and products.

  6. Overexpression of Lysine-Specific Demethylase (show MBD2 ELISA Kits) 1 Is Associated With Tumor Progression in Endometrioid Endometrial Adenocarcinoma.

  7. When LSD1 activity was below 50%, pluripotency of human induced pluripotent stem cells was impaired

  8. Based on the results and analysis, it may provide some useful information for future novel LSD1 inhibitor design.

  9. Results support a model in which the HBXIP (show HBXIP ELISA Kits)/Hotair/LSD1 complex serves as a critical effector of c-Myc (show MYC ELISA Kits) in activating transcription of its target genes, illuminating long-standing questions on how c-Myc (show MYC ELISA Kits) drives carcinogenesis.

  10. These data link the assembly of methylated KDM1A and CHD1 (show CHD1 ELISA Kits) with AR-dependent transcription and genomic translocations, thereby providing mechanistic insight into the formation of TMPRSS2 (show TMPRSS2 ELISA Kits)-ERG (show ERG ELISA Kits) gene fusions during prostate-tumor evolution.

Mouse (Murine) Lysine (K)-Specific Demethylase 1A (KDM1A) interaction partners

  1. Data show that CCAAT-enhancer-binding protein-alpha (C/EBPalpha (show CEBPA ELISA Kits)) directly regulates Kruppel-like factor 4 (Klf4 (show KLF4 ELISA Kits)) expression and increasing the levels of histone demethylase (show MBD2 ELISA Kits) Lsd1 and transcription factor Brd4 (show BRD4 ELISA Kits) in B cell.

  2. Deletion or reduction of isoform neuro LSD1 translates into decreased levels of activating histone marks at egr1 and c-fos promoters, dampening their psychosocial stress-induced transcription and resulting in low anxiety-like behavior.

  3. Rcor2 (show Rcor2 ELISA Kits), a co-repressor of LSD1, controls neurogenesis in the developing mouse brain.

  4. GFI1 (show ZNF163 ELISA Kits) proteins recruit the chromatin-modifying protein LSD1, a member of the CoREST (show Rcor2 ELISA Kits) repressive complex, to epigenetically silence the endothelial program in haemogenic endothelium and allow the emergence of blood cells

  5. LSD1 is essential for oocyte meiotic progression by upregulating CDC25B (show CDC25B ELISA Kits) expression.

  6. This study described how neuronal activity controls the neurospecific splicing of the epigenetic co-repressor LSD1 in mammalian nervous system.

  7. LSD1 mediates erythroid differentiation, via epigenetic modification of the GATA-2 (show GATA2 ELISA Kits) locus.

  8. Kdm1a is a master controller of gene transcription in spermatogonia and is required for SSC (show CYP11A1 ELISA Kits) and progenitor maintenance and differentiation.

  9. KDM1A overexpression in one generation severely impaired development and survivability of offspring.

  10. High LSD1 expression is associated with sickle cell anemia.

Zebrafish Lysine (K)-Specific Demethylase 1A (KDM1A) interaction partners

  1. results suggest that the LSD1-dependent shutdown of Etv2 gene expression may be a significant event required for hemangioblasts to initiate hematopoietic differentiation

  2. Results indicate that LSD1 demethylase (show MBD2 ELISA Kits) activity is required for neuromast development in zebrafish larvae.

Pig (Porcine) Lysine (K)-Specific Demethylase 1A (KDM1A) interaction partners

  1. LSD1 gene has two transcripts and is expressed in various tissues and relatively higher in ovary, kidney, and spleen.

Arabidopsis thaliana Lysine (K)-Specific Demethylase 1A (KDM1A) interaction partners

  1. LSD1, EDS1, and PAD4 (show PADI4 ELISA Kits) participate in the regulation of various molecular and physiological processes that influence Arabidopsis fitness.

  2. AtSWP1 and AtCZS represent two main components of a co-repressor complex that fine tunes flowering and is unique to plants.

  3. AtLSD1, similar to HsLSD1, has demethylase (show MBD2 ELISA Kits) activity toward mono- and dimethylated Lys4 but not dimethylated Lys9 and Lys27 of histone 3. [LSD1]

Lysine (K)-Specific Demethylase 1A (KDM1A) Antigen Profile

Antigen Summary

This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with KDM1A

  • amine oxidase (flavin containing) domain 2 (AOF2) antibody
  • lysine (K)-specific demethylase 1 (KDM1) antibody
  • lysine (K)-specific demethylase 1A (KDM1A) antibody
  • lysine (K)-specific demethylase 1A (kdm1a) antibody
  • lysine (K)-specific demethylase 1A (Kdm1a) antibody
  • lysine (K)-specific demethylase 1a (kdm1a) antibody
  • Lysine-specific histone demethylase 1-1 (LDL1) antibody
  • 1810043O07Rik antibody
  • AA408884 antibody
  • Aof2 antibody
  • ARABIDOPSIS LYSINE-SPECIFIC HISTONE DEMETHYLASE antibody
  • ATLSD1 antibody
  • ATSWP1 antibody
  • BHC110 antibody
  • D4Ertd478e antibody
  • DKFZp459N2450 antibody
  • F23N19.21 antibody
  • F23N19_21 antibody
  • Kdm1 antibody
  • KDM1A antibody
  • Lsd1 antibody
  • LSD1-like 1 antibody
  • LYSINE-SPECIFIC HISTONE DEMETHYLASE antibody
  • mKIAA0601 antibody
  • RGD1562975 antibody
  • SWP1 antibody
  • wu:fb82e06 antibody
  • wu:fc51a02 antibody
  • wu:fj36a05 antibody
  • wu:fj66b06 antibody
  • xLSD1 antibody

Protein level used designations for KDM1A

amine oxidase (flavin containing) domain 2 , lysine (K)-specific demethylase 1 , lysine (K)-specific demethylase 1A , BRAF35-HDAC complex protein BHC110 , FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit , flavin-containing amine oxidase domain-containing protein 2 , lysine-specific histone demethylase 1 , lysine-specific histone demethylase 1A , neuroprotective protein 3 , lsd1

GENE ID SPECIES
419571 Gallus gallus
456614 Pan troglodytes
718609 Macaca mulatta
100171870 Pongo abelii
100216250 Xenopus (Silurana) tropicalis
100557968 Anolis carolinensis
23028 Homo sapiens
99982 Mus musculus
478193 Canis lupus familiaris
500569 Rattus norvegicus
558450 Danio rerio
532997 Bos taurus
100127157 Sus scrofa
842582 Arabidopsis thaliana
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