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MDS1 and EVI1 Complex Locus (MECOM) ELISA Kits

The protein encoded by MECOM is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. Additionally we are shipping MDS1 and EVI1 Complex Locus Antibodies (114) and MDS1 and EVI1 Complex Locus Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MECOM 2122 Q03112 , Q13465
MECOM 14013 Q9Z1L8
Anti-Rat MECOM MECOM 294924  
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Top MDS1 and EVI1 Complex Locus ELISA Kits at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
Details
Human
96 Tests Log in to see 11 to 13 Days
$875.60
Details

More ELISA Kits for MDS1 and EVI1 Complex Locus Interaction Partners

Zebrafish MDS1 and EVI1 Complex Locus (MECOM) interaction partners

  1. nephrogenesis in zebrafish is regulated by interactions between retinoic acid, mecom, and Notch (show NOTCH1 ELISA Kits) signaling

  2. Prdm3 and prdm16 (show PRDM16 ELISA Kits) are strongly expressed in the pharyngeal arches during cranioskeletal development, and their knockdown leads to defects in both the viscerocranium and the neurocranium.

Human MDS1 and EVI1 Complex Locus (MECOM) interaction partners

  1. we identified rs2249650 and rs2268276 as new AML (show RUNX1 ELISA Kits) susceptibility-associated SNPs. Genome editing at rs2249650 and rs2268276 may be performed in future to uncover the effect of this potential RUNX1 (show RUNX1 ELISA Kits) enhancer region.

  2. RUNX1 (show RUNX1 ELISA Kits) and FKBP7 (show FKBP7 ELISA Kits), involved in erythropoesis and muscle protein synthesis, respectively, are related to change in cardiorespiratory fitness in response to exercise.

  3. HTLF (show FOXN2 ELISA Kits) is a RUNX1 (show RUNX1 ELISA Kits) target whose down-regulation promotes genomic instability and correlates with complex cytogenetic abnormalities in acute myeloid leukemia (show BCL11A ELISA Kits) patients.

  4. High RUNX1 (show RUNX1 ELISA Kits) expression is associated with breast cancer.

  5. The Leukemia Inhibitory Factor Receptor (show LIFR ELISA Kits) Gene Is a Direct Target of RUNX1 (show RUNX1 ELISA Kits)

  6. the tumor-suppressor runt (show RUNX1 ELISA Kits) domain transcription factor 1 (show HNF1A ELISA Kits) (RUNX1 (show RUNX1 ELISA Kits)) was confirmed to be a downstream molecule of H19 (show NCKAP1 ELISA Kits)/miR (show MLXIP ELISA Kits)-675 axis, since overexpression of H19 (show NCKAP1 ELISA Kits) or miR (show MLXIP ELISA Kits)-675 significantly decreased RUNX1 (show RUNX1 ELISA Kits) expression in Gastric Cancer cells

  7. Isochromosome 3q, especially MECOM abnormality, could play a key role in Persistent polyclonal binucleated B-cell lymphocytosis.

  8. Low expression of RUNX1 (show RUNX1 ELISA Kits) is associated with malignant progression of gastric cancer.

  9. MECOM deletion is associated with congenital thrombocytopenia.

  10. ETV6 (show ETV6 ELISA Kits)/RUNX1 (show RUNX1 ELISA Kits) transcript is a target of RNA-binding protein (show PTBP1 ELISA Kits) IGF2BP1 (show IGF2BP1 ELISA Kits) in t(12;21)(p13;q22)-positive acute lymphoblastic leukemia.

Mouse (Murine) MDS1 and EVI1 Complex Locus (MECOM) interaction partners

  1. the DNA sequences to which EVI1 binds at +35 and +37 kb and show that mutation of one of these releases Cebpa (show CEBPA ELISA Kits) from EVI1-induced suppression.

  2. Evi1(+)DA-3 cells modified to express an intracellular form of GM-CSF (show CSF2 ELISA Kits), acquired growth factor independence and transplantability and caused an overt leukemia in syngeneic hosts, without increasing serum GM-CSF (show CSF2 ELISA Kits) levels.

  3. Survivin (show BIRC5 ELISA Kits) partially regulates HSC (show FUT1 ELISA Kits) function by modulating the Evi-1 transcription factor and its downstream targets

  4. Thrombopoietin (show THPO ELISA Kits)/MPL (show MPL ELISA Kits) signaling confers growth and survival capacity to CD41-positive cells in a mouse model of Evi1 leukemia.

  5. Prdm16 (show PRDM16 ELISA Kits) and Prdm3 control postnatal BAT (show BAAT ELISA Kits) identity and function.

  6. Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects.

  7. PR-domain protein ME has an essential role in mixed-lineage leukemia (MLL (show MLL ELISA Kits)) fusion protein (MFP) leukemia

  8. Cotransduction of Evi1 and the shortest isoform of C/EBPbeta (show CEBPB ELISA Kits), liver inhibitory protein (LIP), induced acute myeloid leukemia (show BCL11A ELISA Kits) with short latencies in a mouse bone marow transplantation model.

  9. Transient Evi1 transfection inhibited TGF-beta (show TGFB1 ELISA Kits)-induced transcriptional activity and reversed the growth inhibitory effect of TGF-beta (show TGFB1 ELISA Kits) in MC-26 (show Glycam1 ELISA Kits) mouse colon cancer cells.

  10. Evi1 is a key regulator of adipogenic competency

MDS1 and EVI1 Complex Locus (MECOM) Antigen Profile

Antigen Summary

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MECOM

  • MDS1 and EVI1 complex locus (mecom) antibody
  • MDS1 and EVI1 complex locus (MECOM) antibody
  • MDS1 and EVI1 complex locus (LOC100343228) antibody
  • MDS1 and EVI1 complex locus (Mecom) antibody
  • runt-related transcription factor 1 (RUNX1) antibody
  • AML1 antibody
  • AML1-EVI-1 antibody
  • AMLCR1 antibody
  • CBFA2 antibody
  • D630039M04Rik antibody
  • EVI-1 antibody
  • Evi1 antibody
  • im:7140716 antibody
  • Jbo antibody
  • Mds antibody
  • Mds1 antibody
  • Mds1-Evi1 antibody
  • PEBP2aB antibody
  • Prdm3 antibody
  • Znfpr1b1 antibody

Protein level used designations for MECOM

ecotropic viral integration site 1 , PR domain containing 3 , MDS1 and EVI1 complex locus , MDS1 and EVI1 complex locus protein EVI1-like , AML1-EVI-1 fusion protein , MDS1 and EVI1 complex locus protein EVI1 , MDS1 and EVI1 complex locus protein MDS1 , ecotropic virus integration site 1 protein homolog , myelodysplasia syndrome-associated protein 1 , oncogene EVI1 , zinc finger protein Evi1 , ecotropic virus integration site 1 protein , myelodysplasia syndrome 1 homolog , myelodysplasia syndrome 1 protein homolog , CBF-alpha-2 , PEA2-alpha B , PEBP2-alpha B , SL3-3 enhancer factor 1 alpha B subunit , SL3/AKV core-binding factor alpha B subunit , acute myeloid leukemia 1 protein , core-binding factor, runt domain, alpha subunit 2 , oncogene AML-1 , polyomavirus enhancer-binding protein 2 alpha B subunit

GENE ID SPECIES
497407 Danio rerio
460837 Pan troglodytes
698603 Macaca mulatta
100343228 Oryctolagus cuniculus
100403987 Callithrix jacchus
100591579 Nomascus leucogenys
2122 Homo sapiens
14013 Mus musculus
424997 Gallus gallus
488148 Canis lupus familiaris
532209 Bos taurus
294924 Rattus norvegicus
861 Homo sapiens
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