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MAGEA3 is a member of the MAGEA gene family. Additionally we are shipping MAGEA3 Antibodies (79) and and many more products for this protein.
Showing 8 out of 11 products:
Human MAGEA3 Protein expressed in Escherichia coli (E. coli) - ABIN667830
Jang, Soria, Wang, Hassan, Morice, Walsh, Hong, Mao: Activation of melanoma antigen tumor antigens occurs early in lung carcinogenesis. in Cancer research 2001
Show all 2 references for ABIN667830
Comparing the overall expression of CTAs, a decreased expression of all melanoma-associated (show ZNF654 Proteins) antigens (MAGEs) post-treatment and a slightly increased expression of New York esophageal squamous cell carcinoma 1 (NY-ESO-1 (show CTAG1B Proteins)) was visible. The simultaneous cytoplasmic and nuclear expression of pan-MAGE (show MAGEB10 Proteins) or MAGE-A3/A4 correlated with reduced treatment-failure-free-survival (TFFS).
MAGE-A3 expression is regulated epigenetically by promoter methylation, and that its expression contributes to gastric cell proliferation and drug sensitivity.
Progression free survival and levels of MAGE-A3 expression in non-small cell lung carcinoma patients with the three modes of acquired resistance are negatively correlated.
the crystal structures of MAGE-A3 and MAGE-A4 (show MAGEA4 Proteins)
MAGEA3/6 positivity was associated with significantly better disease-free survival.
Anticancer effects of adenovirus-mediated calreticulin (show CALR Proteins) and melanoma-associated antigen 3 expression on non-small cell lung cancer cells
our findings indicated that MAGE-A3 is a novel cancer stem cell antigen in bladder cancer
MAGE-A3 may serve as a potential prognostic marker for clear cell renal cell carcinoma (show MOK Proteins)
Study describes a widespread mechanism to suppress AMPK (show PRKAA1 Proteins) through its ubiquitination and degradation by the cancer-specific MAGE-A3/6-TRIM28 (show TRIM28 Proteins) ubiquitin ligase. MAGE-A3 and MAGE-A6 (show MAGEA6 Proteins) are highly similar proteins normally expressed only in the male germline but frequently re-activated in human cancers.
MAGE (show MAGEB10 Proteins) proteins bind to KAP1 (show CDKN3 Proteins), a gene repressor and ubiquitin E3 ligase which also binds KRAB domain containing zinc finger transcription factors (KZNFs), and MAGE (show MAGEB10 Proteins) expression may affect KZNF mediated gene regulation.
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.
melanoma antigen family A, 3
, MAGE-3 antigen
, antigen MZ2-D
, cancer/testis antigen 1.3
, cancer/testis antigen family 1, member 3
, melanoma-associated antigen 3