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Mitochondrial Poly(A) Polymerase Proteins (MTPAP)

The protein encoded by MTPAP is a member of the DNA polymerase type-B-like family. Additionally we are shipping Mitochondrial Poly(A) Polymerase Antibodies (10) and Mitochondrial Poly(A) Polymerase Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MTPAP 55149 Q9NVV4
MTPAP 67440 Q9D0D3
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Top Mitochondrial Poly(A) Polymerase Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 59 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 59 Days
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days

MTPAP Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

More Proteins for Mitochondrial Poly(A) Polymerase (MTPAP) Interaction Partners

Human Mitochondrial Poly(A) Polymerase (MTPAP) interaction partners

  1. Mitochondrial poly(A) polymerase is able to add the discriminator adenosine to tRNATyr.

  2. The polymerase activity of mtPAP is modulated by LRPPRC (show LRPPRC Proteins)/SLIRP; N478D mtPAP mutation decreases its activity and the alteration in poly(A) length causes dysregulation of post-transcriptional expression and lack of respiratory chain complexes.

  3. Mutation of the MTPAP gene results in a cellular phenotype of increased DNA damage, reduced repair kinetics, increased cell death by apoptosis, and reduced clonogenic survival after exposure to ionizing radiation.

  4. show that dimerization is required for the catalytic activity of PAPD1

  5. Characterization of this marker shows that it is orthologous to the human gene KIAA1462 located on HSA10p11.23, where a major quantitative trait locus for morbid obesity has been reported.

  6. Cloning of a human nuclear-encoded mitochondrial poly(A) polymerase (hmtPAP)that has a role in mitochondrial RNA processing.

Mitochondrial Poly(A) Polymerase (MTPAP) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the DNA polymerase type-B-like family. This enzyme synthesizes the 3' poly(A) tail of mitochondrial transcripts and plays a role in replication-dependent histone mRNA degradation.

Gene names and symbols associated with MTPAP

  • mitochondrial poly(A) polymerase (MTPAP)
  • mitochondrial poly(A) polymerase (Mtpap)
  • 0610027A18Rik protein
  • AW551379 protein
  • Papd1 protein
  • SPAX4 protein

Protein level used designations for MTPAP

PAP-associated domain-containing protein 1 , TUTase 1 , poly(A) RNA polymerase, mitochondrial , polynucleotide adenylyltransferase , terminal uridylyltransferase 1 , PAP associated domain containing 1

55149 Homo sapiens
67440 Mus musculus
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