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MUC2 encodes a member of the mucin protein family. Additionally we are shipping MUC2 Antibodies (238) and MUC2 Proteins (17) and many more products for this protein.
Showing 10 out of 52 products:
Human MUC2 ELISA Kit for Sandwich ELISA - ABIN414718
Maker, Katabi, Gonen, DeMatteo, DAngelica, Fong, Jarnagin, Brennan, Allen: Pancreatic cyst fluid and serum mucin levels predict dysplasia in intraductal papillary mucinous neoplasms of the pancreas. in Annals of surgical oncology 2011
Show all 3 Pubmed References
Rat (Rattus) MUC2 ELISA Kit for Sandwich ELISA - ABIN431781
Yamamoto, Itoh, Nasu, Nishida: Sodium alginate ameliorates indomethacin-induced gastrointestinal mucosal injury via inhibiting translocation in rats. in World journal of gastroenterology : WJG 2014
Mouse (Murine) MUC2 ELISA Kit for Sandwich ELISA - ABIN424172
Li, Liang, Li, Wang, Zhang, Gao, Wen, Tang: Fecal microbiota transplantation and bacterial consortium transplantation have comparable effects on the re-establishment of mucosal barrier function in mice with intestinal dysbiosis. in Frontiers in microbiology 2015
The goblet cell-derived RELM-beta (show RETNLB ELISA Kits) drives spontaneous colitis in Muc2-deficient mice by promoting commensal microbial dysbiosis.
The major responsible region for MUC2 expression exists in amino acids 1-36 of SAA3 (show SAA3 ELISA Kits).
loss of KLF4 (show KLF4 ELISA Kits) and expression of MUC2 could be important markers for gastric cancer diagnosis.
These studies demonstrate regulatory mechanisms between MUC2 and cathelicidins in the colonic mucosa where an intact mucus barrier is essential for expression and secretion of cathelicidins in response to E. histolytica- and DSS (show PMP22 ELISA Kits)-induced colitis.
the intestinal specificity of mucin 2 (MUC2) expression was identified in mice and humans, and further confirmed in chickens.
This triggers calcium ion-dependent compound exocytosis of Muc2 mucin (show SLC13A2 ELISA Kits) from the senGC and generates an intercellular gap junction signal; in turn, this signal induces Muc2 secretion from adjacent goblet cells in the upper crypt, which expels bacteria.
HIF-1alpha (show HIF1A ELISA Kits) inhibition decreases MUC2 production and mucinous tumor growth, providing a preclinical rationale for the use of HIF-1alpha (show HIF1A ELISA Kits) inhibitors to treat patients with PMP
colitic Muc2-/- mice have reduced colon CD103 (show ITGAE ELISA Kits)+ CD11b (show ITGAM ELISA Kits)- dendritic cells and increased CD103 (show ITGAE ELISA Kits)- CD11b (show ITGAM ELISA Kits)+ phagocytes.
expression of MUC2 mRNA is found to be more expressed in Eimeria infected females than males
MUC2 silencing increases interleukin (IL)-6 (show IL6 ELISA Kits) secretion by colon cancer cells.
Our association of MUC2 in the Dutch ulcerative colitis population could not be replicated in a German cohort, this might be because our associated SNVs are population specific or because of a lack of power.
Among the mild and moderate/severe intestinal metaplasia of gastric mucosa specimens, the relative expression levels of MUC2, a gastrointestinal differentiation marker, were elevated by approximately 6.2- and 21.4-fold
loss of MUC2 expression proved to be a predictor of adverse outcome, while the gain of aberrant expression of MUC5AC and particularly of MUC6 (show MUC6 ELISA Kits) was associated with favorable outcome in colorectal cancer, notably in intermediate stages II and III
This shows for the first time that transamidation is not only stabilizing the skin and the fibrin clot (show TXNDC17 ELISA Kits), but is also important for the correct intracellular processing of MUC2 to generate protective mucus.
Immunohistochemistry showed a reverse correlation between MUC2 and Notch3 or Jagged1 (P = 0.033 and P = 0.005, respectively) and between MUC5AC and Jagged1 or Hes1
Our results unraveled an important regulatory role for MUC2 mucin (show SLC13A2 ELISA Kits) in human beta-defensin2 mRNA and peptide production in a proinflammatory milieu
There was no significant difference in MUC2 expression between chronic rhinosinusitis patients with and without bacterial biofilm formation.
In ovarian mucinous tumors, MUC2 expression changes with the progression of benign to borderline and malignant tumours
identified a specific depletion of secreted MUC2 from goblet cells in Lawsonia intracellularis-infected pigs that correlated with the increased level of intracellular bacteria in crypt cells
The structures of purified soluble porcine gastric (Muc5ac) and duodenal (Muc2) mucin (show SLC13A2 ELISA Kits) solutions at neutral and acidic pH were examined using small-angle X-ray scattering and small-angle neutron scattering experiments
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
, secreted gel-forming mucin
, intestinal mucin-2
, mucin 2, intestinal/tracheal
, mucin-like protein