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Myocilin (MYOC) ELISA Kits

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. Additionally we are shipping Myocilin Antibodies (58) and Myocilin Proteins (23) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse MYOC MYOC 17926 O70624
MYOC 4653 Q99972
Anti-Rat MYOC MYOC 81523 Q9R1J4
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Top Myocilin ELISA Kits at

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.039 U/mL 0.156-10 U/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days

More ELISA Kits for Myocilin Interaction Partners

Mouse (Murine) Myocilin (MYOC) interaction partners

  1. Mutated myocilin and heterozygous Sod2 (show SOD2 ELISA Kits) deficiency act synergistically in a mouse model of open-angle glaucoma

  2. myocilin promotes cell proliferation and resistance to apoptosis via the ERK1/2 (show MAPK1/3 ELISA Kits) MAPK (show MAPK1 ELISA Kits) signaling pathway.

  3. Myocilin binds to ErbB2 (show ERBB2 ELISA Kits)/ErbB3 (show ERBB3 ELISA Kits), activates these receptors, and affects the downstream PI3K-AKT (show AKT1 ELISA Kits) signaling pathway

  4. Myocilin also stimulated osteogenic differentiation of wild-type MSCs, which was associated with activation of the p38 (show CRK ELISA Kits), Erk1/2 (show MAPK1/3 ELISA Kits), and JNK (show MAPK8 ELISA Kits) MAP kinase (show MAPK1 ELISA Kits) signaling pathways

  5. We suggest that intracellular myocilin plays a role as a regulator of muscle hypertrophy pathways, acting through the components of dystrophin (show DMD ELISA Kits) associated protein complex.

  6. The TIGR is implicated in resistance to oxidative stress. Despite the presence of a SOD motif, which is necessary for protection in mammalian cells, the protein is not a functional SOD, but might be involved in SOD activity.

  7. TIGR is a newly identified component of the CNS glial scar that is likely to contribute to neuronal regenerative failure characteristic of the mammalian CNS.

  8. Results do not support a causative role for increased MYOC levels or the MYOC gene in steroid-induced glaucoma.

  9. Results show that myocilin and gamma-synuclein (show SNCG ELISA Kits) interact and as a result, myocilin's properties are changed.

  10. These data suggest that production, apparent misfolding, and nonsecretion of mutant MYOC are not, by themselves, sufficient to cause glaucoma in vivo.

Human Myocilin (MYOC) interaction partners

  1. Familial linkage studies for primary angle-closure glaucoma have been performed and identified MYOC causative primary angle-closure glaucoma disease

  2. The rate of CYP1B1 (show CYP1B1 ELISA Kits) mutations in Lebanese patients with primary congenital glaucoma (PCG) is lower than that reported in other Arab and Middle Eastern populations and suggests other genes are responsible.

  3. Data show that predictive genetic testing for early onset Myocilin glaucoma can facilitate early detection of disease or discharge from routine ophthalmic examinations.

  4. This study does not confirm a role for genetic variants in the MYOC, NR3C1 (show NR3C1 ELISA Kits) and FKBP5 (show FKBP5 ELISA Kits) genes in the pathogenesis of corticosteroid-induced ocular hypertension.

  5. Glaucomatous MYOC mutations activate the IL-1beta (show IL1B ELISA Kits)/NF-kappaB (show NFKB1 ELISA Kits) inflammatory stress response and the glaucoma marker SELE (show SELE ELISA Kits) in trabecular meshwork cells.

  6. Secondary structure prediction of the Ser341Pro MYOC gene mutation suggested that the MYOC protein was misfolded.

  7. Mutations in myoc ofactomedin domain are causative in the autosomal dominant inherited form of the prevalent ocular disorder glaucoma.

  8. A novel heterozygous missense mutation c.761CMYOC gene was identified as being co-segregated with the primary open-angle glaucoma phenotype in this family.

  9. All POAG samples underwent full sequencing of the MYOC gene, and we found a sensitivity of 100%, specificity of 99.91%, positive predictive value of 95.65%, and negative predictive value of 100% between imputation and sequencing.

  10. FAs (show FAS ELISA Kits), expression of fibrogenic markers, and myocilin in HTM cells. These characteristics of Hic-5 (show TGFB1I1 ELISA Kits) in TM cells indicate its importance in regulation of AH outflow through the TM in both normal and glaucomatous eyes.

Cow (Bovine) Myocilin (MYOC) interaction partners

  1. endoproteolytic processing might regulate the activity of myocilin; the inhibition of the processing by pathogenic mutations impairs the normal role of myocilin

Myocilin (MYOC) Antigen Profile

Antigen Summary

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

Gene names and symbols associated with Myocilin (MYOC) ELISA Kits

  • myocilin (MYOC) antibody
  • myocilin (myoc) antibody
  • myocilin (Myoc) antibody
  • myocilin, trabecular meshwork inducible glucocorticoid response (MYOC) antibody
  • myocilin, trabecular meshwork inducible glucocorticoid response (Myoc) antibody
  • AI957332 antibody
  • GLC1A antibody
  • GPOA antibody
  • JOAG antibody
  • JOAG1 antibody
  • MGC136645 antibody
  • MYOC antibody
  • myocilin antibody
  • Tigr antibody
  • zgc:136645 antibody

Protein level used designations for Myocilin (MYOC) ELISA Kits

myocilin , trabecular meshwork-induced glucocorticoid response protein , mutated trabecular meshwork-induced glucocorticoid response protein

397046 Sus scrofa
548602 Danio rerio
704406 Macaca mulatta
17926 Mus musculus
4653 Homo sapiens
81523 Rattus norvegicus
281342 Bos taurus
101087632 Felis catus
490344 Canis lupus familiaris
100008897 Oryctolagus cuniculus
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