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Striated muscle in vertebrates comprises large proteins which must be organized properly to contract efficiently. Additionally we are shipping Myopalladin Antibodies (38) and Myopalladin Proteins (5) and many more products for this protein.
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results suggest that MYPN screening should be considered in individuals with mild nemaline myopathy, especially when cardiac problems or intranuclear rods are present
Heterozygote Mypn(WT/Q526X) knock-in mice develop RCM (show Unc5c ELISA Kits) due to persistence of mutant Mypn(Q526X) protein in the nucleus.
the clinical significance of myopalladin for the functional integrity of the sarcomeric apparatus and the protection against dilated cardiomyopathy
Two nonsense and 13 missense MYPN variants were identified in subjects with hypertrophic, dilated and/or restrictive cardiomyopathy.
mutations in PDLIM3 (show PDLIM3 ELISA Kits) and MYPN are infrequent in hypertrophic cardiomyopathies
myopalladin plays a signaling role in targeting and orienting nebulin (show NEB ELISA Kits) during sarcomere assembly
myopalladin gene is a new gene associated with dilated cardiomyopathy and observed mutations in 3-4% of cases in a population. of European descent.
Two polymorphisms previously identified and described in the 3'UTR (show UTS2R ELISA Kits) of MYPN and TTN (show TTN ELISA Kits) genes in a group of Italian Large White (ILW) and Italian Duroc (ID) pigs, were analysed.
Striated muscle in vertebrates comprises large proteins which must be organized properly to contract efficiently. Z-lines in striated muscle are a sign of this organization, representing the ends of actin thin filaments, titin, nebulin or nebulette and accessory proteins required for structure and function. This gene encodes a protein which interacts with nebulin in skeletal muscle or nebulette in cardiac muscle and alpha-actinin. In addition, this gene product can interact with a protein with the I-band indicating it has a regulatory as well as structural function. Alternative splicing results in multiple transcript variants.
, sarcomeric protein myopalladin, 145 kDa (MYOP)