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Myosin IC Proteins (MYO1C)

MYO1C encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. Additionally we are shipping Myosin IC Antibodies (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MYO1C 4641 O00159
MYO1C 17913 Q9WTI7
MYO1C 65261 Q63355
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Top Myosin IC Proteins at

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 69 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 69 Days
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 9 to 11 Days
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 9 to 16 Days

MYO1C Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Myosin IC (MYO1C) Interaction Partners

Human Myosin IC (MYO1C) interaction partners

  1. Overexpression of MYO1C is associated with gastric cancer.

  2. Coinheritance of COL4A5 (show COL4a5 Proteins) and MYO1E (show MYO1E Proteins) mutations accentuate the severity of kidney disease.

  3. Ablating MYO1C function causes abnormal cholesterol distribution, which has a major selective impact on the autophagy pathway

  4. Myo1c significantly increases the frequency of kinesin-1-driven microtubule-based runs that begin at actin/microtubule intersections. The actin-binding protein (show KPTN Proteins) tropomyosin 2 (show TPM2 Proteins) abolishes Myo1c-specific effects on both run initiation and run termination.

  5. NM1 phosphorylation by GSK3beta blocks NM1 ubiquitination by UBR5 and degradation by the proteasome, leads to NM1 association with the chromatin and promotes rDNA transcription activation at G1.

  6. Myo1e (show MYO1E Proteins) is a key component contributing to the functional integrity of podocytes.

  7. The relationship between MYO1C and KAT6B (show KAT6B Proteins) suggests that the two are interacting in chromatin remodelling for gene expression in human masseter muscle. This is the nuclear myosin1 (NM1) function of MYO1C.

  8. myosin 1c manipulations lead to loss of the actin filaments and to similar endoplasmic reticulum phenotype as observed after actin depolymerization.

  9. MYO1E (show MYO1E Proteins) mutations are not a major cause of Chinese familial Steroid-resistant nephrotic syndrome.

  10. The structural context and the chemical environment of Myo1c mutations that are involved in sensorineural hearing loss in humans are described and their impact on motor function is discussed.

Mouse (Murine) Myosin IC (MYO1C) interaction partners

  1. We propose a novel genome-wide mechanism where myosin synergizes with Pol II-associated actin to link the polymerase machinery with permissive chromatin for transcription activation.

  2. Our observations demonstrate specific changes in the expression of myosin IC isoform A that are concurrent with the occurrence of prostate cancer in the TRAMP (show DPT Proteins) mouse prostate cancer model that closely mimics clinical prostate cancer

  3. Ca(2+) binding to calmodulin induces major conformational changes in both IQ motifs and the post-IQ domain and increases flexibility of the myosin-1c tail.

  4. The v-Crk-myosin-1c interaction, which modulates membrane dynamics by regulating Rac1 activity, is crucial for cell adhesion and spreading.

  5. Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus.

  6. Myo1c functions as a slow transporter rather than a tension-sensitive anchor.

  7. the novel specific NLS (show ALDH1A2 Proteins) brings to the cell nucleus not only the "nuclear" isoform of myosin I (show MYO1A Proteins) (NM1 protein) but also its "cytoplasmic" isoform (Myo1c protein)

  8. The data suggest that Myosin 1c is involved in the cytoskeleton dynamics and membrane protein anchoring or sorting in B lymphocytes

  9. A hearing loss-associated myo1c mutation (R156W) decreases the myosin duty ratio and force sensitivity

  10. The strength and attachment lifetime of single myo1c molecules as they bind beads coated with a bilayer of 2% phosphatidylinositol 4,5-bisphosphate and 98% phosphatidylcholine (show SGMS2 Proteins), were measured.

Zebrafish Myosin IC (MYO1C) interaction partners

  1. Myo1c is necessary for podocyte morphogenesis.

Cow (Bovine) Myosin IC (MYO1C) interaction partners

  1. Vectorial transport of G-actin (show ACTB Proteins) was shown in live migrating endothelial cells. Myo1c (an unconventional F-actin-binding motor protein) was identified as a major G-actin (show ACTB Proteins)-interacting protein. The cargo-binding tail domain of Myo1c interacted with G-actin (show ACTB Proteins).

Myosin IC (MYO1C) Protein Profile

Protein Summary

This gene encodes a member of the nonmuscle class I myosins which are a subgroup of the unconventional myosin protein family. The unconventional myosin proteins function as actin-based molecular motors. Class I myosins are characterized by a head (motor) domain, a regulatory domain and a either a short or long tail domain. Among the class I myosins, this protein is distinguished by a long tail domain that is involved in crosslinking actin filaments. This protein localizes to the cytoplasm and may be involved in intracellular movement and membrane trafficking. Mutations in this gene are the cause of focal segmental glomerulosclerosis-6. This gene has been referred to as myosin IC in the literature but is distinct from the myosin IC gene located on chromosome 17.

Gene names and symbols associated with Myosin IC Proteins (MYO1C)

  • myosin IC (MYO1C)
  • class I myosin (myoC)
  • myosin IC (myoC)
  • myosin IC (myo1c)
  • myosin IC (Myo1c)
  • myosin IC (myo1c-b)
  • myosin IE (MYO1E)
  • si:ch211-69i14.4 (si:ch211-69i14.4)
  • C80397 protein
  • DDBDRAFT_0202969 protein
  • DDBDRAFT_0215355 protein
  • DDB_0202969 protein
  • DDB_0215355 protein
  • FSGS6 protein
  • HuncM-IC protein
  • mm1beta protein
  • MMI-beta protein
  • MMIb protein
  • Myo1c protein
  • MYO1E protein
  • Myosin-Ic protein
  • Myr2 protein
  • nm1 protein
  • NMI protein

Protein level used designations for Myosin IC Proteins (MYO1C)

myosin IC , nuclear myosin 1 , myosin-Ic-like , myosin I beta , myosin-I beta , myosin-Ic , nuclear myosin I , unconventional myosin-Ic , MMI-beta , myosin-Ibeta , nuclear myosin I beta , MMIb , myosin IC-like , myosin heavy chain myr 2 , unconventional myosin Myr2 I heavy chain , MYO1E variant protein , myosin-IC , unconventional myosin 1E , unconventional myosin-Ie , Myosin I beta

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