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anti-Myosin XV (MYO15) Antibodies

Myosins are actin-based motor molecules with ATPase activity. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MYO15 17910 Q9QZZ4
MYO15 51168 Q9UKN7
MYO15 501699  
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Top anti-Myosin XV Antibodies at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged MYO15A is 3 ng/ml as a capture antibody. Western Blot detection against Immunogen (36.63 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 3 to 4 Days
$388.93
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 3 to 4 Days
$388.93
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 3 to 4 Days
$388.93
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 3 to 4 Days
$388.93
Details
Human Mouse Un-conjugated ELISA (Capture), ELISA, WB   100 μg Log in to see 6 to 8 Days
$487.30
Details

MYO15 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Human
,
,
Rat (Rattus)


More Antibodies against Myosin XV Interaction Partners

Fruit Fly (Drosophila melanogaster) Myosin XV (MYO15) interaction partners

  1. suggest a mechanism for Sisyphus (the Drosophila myosin XV homolog) in which it maintains a balance between actin and microtubule cytoskeleton components

Mouse (Murine) Myosin XV (MYO15) interaction partners

  1. Myosin 15 (show MYH15 Antibodies) isoforms can navigate between functionally distinct classes of stereocilia, and are independently required to assemble and then maintain the intricate hair bundle architecture.

  2. myo15-subfragment 1 is a barbed-end-directed motor that moves actin filaments in a gliding assay using a power stroke of 7.9 nm. Myo15-S1 was rate limited by transit through strongly actin-bound states, similar to other processive myosin motors.

  3. It was concluded that MyoXVa, whirlin, and Eps8 are integral components of the stereocilia tip complex, where Eps8 is a central actin-regulatory element for elongation of the stereocilia actin core.

  4. endogenous myosin XVa localizes to the tips of the stereocilia of the cochlear and vestibular hair cells

  5. myosin-XVa is a motor protein (show MYO7A Antibodies) that, in vivo, interacts with the third PDZ domain (show INADL Antibodies) of whirlin (show DFNB31 Antibodies) through its carboxy-terminal PDZ (show INADL Antibodies)-ligand. Myosin-XVa then delivers whirlin (show DFNB31 Antibodies) to the tips of stereocilia.

  6. This comparison revealed that the absence of functional myosin-XVa does not disrupt adaptation of the mechanotransduction current during sustained bundle deflection.

  7. The morphology of cochlear hair cell stereocilia in double mutants reflects a dominance of the more severe Myo15 (sh2/sh2) phenotype over the Whrn (wi/wi (show DFNB31 Antibodies)) phenotype.

  8. The Ca(2 (show CA2 Antibodies)+) sensitivity of the mechanotransduction channels and the fast adaptation require a structural environment that is dependent on myosin-XVa and is disrupted in Myo15(sh2/sh2) inner hair cells, but not in Myo15(sh2/sh2) outer hair cells.

Human Myosin XV (MYO15) interaction partners

  1. Mutations in exon 2 of MYO15A may cause a less severe phenotype, facilitating the rapid identification of mutations in exon 2 among the 66 exons when linkage of less severe hearing loss to DFNB3 is detected

  2. MYO15A mutations that affect domains other than the N-terminal domain, lead to profound sensorineural hearing loss throughout all frequencies.

  3. MYO15A Mutation is associated with Autosomal Recessive Nonsyndromic Hearing Loss.

  4. Mutations in the MYO15A gene are a notable cause of nonsyndromic hearing loss.

  5. Data indicate nine novel mutations in the genes encoding myosin VI (show MYO6 Antibodies), myosin VIIA (show MYO7A Antibodies) and myosin XVA in hearing-impaired individuals from Israeli Jewish and Palestinian Arab families.

  6. MYO15A c.IVS25+3G>A and c.8375 T>C (p.V2792A) as the autosomal recessive hearing loss-causing mutations

  7. study found two novel compound heterozygous mutations of MYO15A and 13 nonsynonymous variants in the coding exons of MYO15A from Korean exomes in families with autosomal recessive nonsyndromic hearing loss

  8. sequencing of the MYO15A gene led to identification of 7 previously unreported mutations, including 4 missense mutations, 1 nonsense mutation, and 2 deletions in different regions of the myosin-XV protein

  9. the second exon of MYO15A from the DNA of all affected individuals ofHEARING LOSS IN A family revealed a duplication of Cytosine in a stretch of seven repetitive C nucleotides (c.1185dupC).

  10. Estimation of the prevalence of homozygous MYO15A mutations in autosomal recessive nonsyndromic deafness in Turkey as 0.062 (95% confidence interval is 0.020-0.105).

Myosin XV (MYO15) Antigen Profile

Protein Summary

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity). Required for the arrangement of stereocilia in mature hair bundles.

Gene names and symbols associated with anti-Myosin XV (MYO15) Antibodies

  • Myosin 10A (Myo10A) antibody
  • myosin XVA (MYO15A) antibody
  • myosin xv (AaeL_AAEL011436) antibody
  • myosin xv (CpipJ_CPIJ016115) antibody
  • myosin XV (Smp_127510) antibody
  • myosin XV (Myo15) antibody
  • myosin XVA (Myo15a) antibody
  • 10A antibody
  • AAF47980 antibody
  • CG2136 antibody
  • CG2174 antibody
  • CG16922 antibody
  • CG43657 antibody
  • DFNB3 antibody
  • Dmel\\CG43657 antibody
  • Dmel_CG2174 antibody
  • Dmel_CG16922 antibody
  • DmXV antibody
  • myo10A antibody
  • Myo15 antibody
  • Myo15a antibody
  • RGD1561873 antibody
  • sh-2 antibody
  • sh2 antibody
  • Syph antibody

Protein level used designations for anti-Myosin XV (MYO15) Antibodies

CG43657-PC , CG43657-PD , CG43657-PE , Myo10A-PC , Myo10A-PD , Myo10A-PE , myosin 10A , myosin XV , sisyphus , unconventional myosin class XV , myosin XVA , myosin xv , myosin-XV , shaker 2 , unconventional myosin-15 , unconventional myosin-XV

GENE ID SPECIES
32028 Drosophila melanogaster
454485 Pan troglodytes
5574835 Aedes aegypti
6049401 Culex quinquefasciatus
8353008 Schistosoma mansoni
17910 Mus musculus
51168 Homo sapiens
501699 Rattus norvegicus
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