Nemo-Like Kinase (NLK) ELISA Kits

Serine/threonine-protein kinase that regulates a number of transcription factors with key roles in cell fate determination. Additionally we are shipping Nemo-Like Kinase Antibodies (113) and Nemo-Like Kinase Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
NLK 14751 P06745
NLK 292804 Q6P6V0
NLK 51701 Q9UBE8
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More ELISA Kits for Nemo-Like Kinase Interaction Partners

Mouse (Murine) Nemo-Like Kinase (NLK) interaction partners

  1. our data suggest that NLK/Nemo (show IKBKG ELISA Kits) acts as an endogenous regulator of Hippo signaling by controlling nuclear localization and activity of YAP/Yorkie (show YAP1 ELISA Kits).

  2. NLK is a novel signaling molecule for proper lung development through the interconnection between epithelial and endothelial cells during lung morphogenesis

  3. NLK can phosphorylate the mutant polyglutamine-expanded androgen receptor (show AR ELISA Kits) protein, enhance its aggregation, and promote androgen receptor (show AR ELISA Kits)-dependent gene transcription by regulating androgen receptor (show AR ELISA Kits)-cofactor interactions.

  4. Nlk is a negative regulator of skeletal homeostasis.

  5. PGI (show BGN ELISA Kits) is a moonlighting protein that functions as a cytosolic enzyme involved in glycolysis and gluconeogenesis, and as cytokine through binding to its cell surface receptor.

  6. The mGPI-transgenic mice presented GPI (show GPI ELISA Kits) more efficiently and showed a dramatic increase in negative selection and an inhibition of arthritis.

  7. either reducing NLK enzymatic activity or decreasing NLK expression levels can have beneficial effects against the toxicity induced by polyglutamine-expanded ATXN1 (show ATXN1 ELISA Kits)

  8. Increased red cell turnover in a line of CD22 (show CD22 ELISA Kits)-deficient mice is caused by Gpi1c: a model for hereditary haemolytic anaemia.

  9. NEMO (show IKBKG ELISA Kits) binding domain peptide treatment results in improved generation of specific force and greater resistance to lengthening activations in dystrophic diaphragm muscle ex vivo.

  10. Nlk suppresses osteoblastogenesis by opposing BMP/Smad (show SMAD1 ELISA Kits) and WNT (show WNT2 ELISA Kits) canonical signaling

Zebrafish Nemo-Like Kinase (NLK) interaction partners

  1. NLK negatively regulates Notch (show NOTCH1 ELISA Kits)-dependent transcriptional activation by phosphorylating Notch1ICD. Phosphorylated Notch1ICD is impaired in its ability to form a transcriptionally active ternary complex.

  2. nlk strongly enhances convergent/extension phenotypes, suggesting a role in modulating cell movements as well as cell fate.

Xenopus laevis Nemo-Like Kinase (NLK) interaction partners

  1. NLK1 acts as a kinase by catalyzing phosphorylation of pumilio (Pum)1, Pum2, and cytoplasmic polyadenylation element binding protein 1 (CPEB) to regulate translation of mRNAs, including cyclin B1 mRNA, stored in oocytes.

  2. These results provide the first evidence that p38 (show MAPK14 ELISA Kits) specifically regulates NLK function, which is required for anterior formation in Xenopus development.

Human Nemo-Like Kinase (NLK) interaction partners

  1. our data suggest that NLK/Nemo (show IKBKG ELISA Kits) acts as an endogenous regulator of Hippo signaling by controlling nuclear localization and activity of YAP/Yorkie (show YAP1 ELISA Kits).

  2. NLK is a novel signaling molecule for proper lung development through the interconnection between epithelial and endothelial cells during lung morphogenesis

  3. Our results suggest that NLK inhibits transcriptional activation of Nurr1 (show NR4A2 ELISA Kits) gene by impeding CBP's role as a co-activator of NF-kappaB (show NFKB1 ELISA Kits) and CREB (show CREB1 ELISA Kits) in prostate cancer.

  4. The expression of NLK was negatively correlated with TCF4 (show TCF4 ELISA Kits) expression in lung cancers

  5. NLK overexpression is an independent prognostic factor in colorectal cancer and knockdown of NLK expression inhibits colorectal cancer progression and metastasis.

  6. Further experiments demonstrated that the overexpression of miR3623p resulted in decrease expression levels of nemo-like kinase

  7. NLK was involved in miR (show MLXIP ELISA Kits)-92b-induced cell proliferation, and its protein level was obviously downregulated in the miR (show MLXIP ELISA Kits)-92b-overexpressing xenograft tumors.

  8. Data show that metformin inhibits nemo like kinase (NLK) expression and might be a potential treatment strategy for non-small cell lung cancer (NSCLC).

  9. Down-regulation of NLK inhibited tumorigenesis and up-regulated the expression of cell cycle proteins in laryngeal cancer cells.

  10. In this review, we will make a summary on the comprehensive roles of NLK in the regulation of various cancers

Pig (Porcine) Nemo-Like Kinase (NLK) interaction partners

  1. These data show that porcine epidemic diarrhea virus nsp5 disrupts type I interferon (show IFNA ELISA Kits) signaling by cleaving NEMO (show IKBKG ELISA Kits).

Nemo-Like Kinase (NLK) Antigen Profile

Antigen Summary

Serine/threonine-protein kinase that regulates a number of transcription factors with key roles in cell fate determination. Positive effector of the non-canonical Wnt signaling pathway, acting downstream of WNT5A, MAP3K7/TAK1 and HIPK2. Activation of this pathway causes binding to and phosphorylation of the histone methyltransferase SETDB1. The NLK- SETDB1 complex subsequently interacts with PPARG, leading to methylation of PPARG target promoters at histone H3K9 and transcriptional silencing. The resulting loss of PPARG target gene transcription inhibits adipogenesis and promotes osteoblastogenesis in mesenchymal stem cells (MSCs). Negative regulator of the canonical Wnt/beta-catenin signaling pathway. Binds to and phosphorylates TCF7L2/TCF4 and LEF1, promoting the dissociation of the TCF7L2/LEF1/beta-catenin complex from DNA, as well as the ubiquitination and subsequent proteolysis of LEF1. Together these effects inhibit the transcriptional activation of canonical Wnt/beta-catenin target genes. Negative regulator of the Notch signaling pathway. Binds to and phosphorylates NOTCH1, thereby preventing the formation of a transcriptionally active ternary complex of NOTCH1, RBPJ/RBPSUH and MAML1. Negative regulator of the MYB family of transcription factors. Phosphorylation of MYB leads to its subsequent proteolysis while phosphorylation of MYBL1 and MYBL2 inhibits their interaction with the coactivator CREBBP. Other transcription factors may also be inhibited by direct phosphorylation of CREBBP itself. Acts downstream of IL6 and MAP3K7/TAK1 to phosphorylate STAT3, which is in turn required for activation of NLK by MAP3K7/TAK1 (By similarity).

Gene names and symbols associated with Nemo-Like Kinase (NLK) ELISA Kits

  • glucose phosphate isomerase 1 (Gpi1) antibody
  • nemo-like kinase (NLK) antibody
  • nemo like kinase, type 1 (nlk1) antibody
  • nemo-like kinase (nlk) antibody
  • Nemo-like kinase (NLK) antibody
  • Nemo-Like kinase (nemo-like) antibody
  • glucose-6-phosphate isomerase (Gpi) antibody
  • nemo like kinase (Nlk) antibody
  • AI194375 antibody
  • Amf antibody
  • Gpi antibody
  • Gpi-1 antibody
  • Gpi-1r antibody
  • Gpi-1s antibody
  • Gpi-1t antibody
  • Gpi1 antibody
  • Gpi1-r antibody
  • Gpi1-s antibody
  • Gpi1-t antibody
  • Gpi1s antibody
  • MF antibody
  • nemo-like antibody
  • NK antibody
  • NK/GPI antibody
  • NLK antibody
  • nlk1 antibody
  • nlk2 antibody
  • nlkb antibody
  • Org antibody
  • RGD1561602 antibody
  • Xnlk antibody
  • zgc:111875 antibody

Protein level used designations for Nemo-Like Kinase (NLK) ELISA Kits

NLK , PGI , PHI , autocrine motility factor , glucose phosphate isomerase 1 complex , glucose phosphate isomerase 1, regulatory , glucose phosphate isomerase 1, structural , glucose phosphate isomerase 1, temporal , glucose-6-phosphate isomerase , maturation factor , neuroleukin , phosphoglucose isomerase , phosphohexose isomerase , structural glucose phosphate isomerase 1 , nemo like kinase b , nemo-like kinase , nemo-like kinase 2 , Nemo-like kinase , nemo like kinase , Nemo-Like kinase , serine/threonine-protein kinase NLK-like , glucose phosphate isomerase , serine/threonine protein kinase NLK , serine/threonine-protein kinase NLK , Serine/threonine-protein kinase NLK

GENE ID SPECIES
14751 Mus musculus
100058876 Equus caballus
405892 Danio rerio
414522 Xenopus laevis
445934 Takifugu rubripes
677693 Macaca mulatta
739132 Pan troglodytes
778685 Ciona intestinalis
100019356 Monodelphis domestica
100144638 Xenopus (Silurana) tropicalis
100348930 Oryctolagus cuniculus
100414864 Callithrix jacchus
100469296 Ailuropoda melanoleuca
100560802 Anolis carolinensis
100593981 Nomascus leucogenys
292804 Rattus norvegicus
18099 Mus musculus
497961 Rattus norvegicus
51701 Homo sapiens
507204 Bos taurus
491160 Canis lupus familiaris
417669 Gallus gallus
100511657 Sus scrofa
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