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NTN4 belongs to a family of proteins related to laminins (see LAMA1, MIM 150320) Koch et al. Additionally we are shipping Netrin 4 Kits (18) and Netrin 4 Proteins (3) and many more products for this protein.
Showing 10 out of 59 products:
Cow (Bovine) Polyclonal Netrin 4 Primary Antibody for IHC, WB - ABIN2783832
Esseghir, Kennedy, Seedhar, Nerurkar, Poulsom, Reis-Filho, Isacke: Identification of NTN4, TRA1, and STC2 as prognostic markers in breast cancer in a screen for signal sequence encoding proteins. in Clinical cancer research : an official journal of the American Association for Cancer Research 2007
Human Polyclonal Netrin 4 Primary Antibody for IHC, IHC (p) - ABIN4340879
Jayachandran, Prithviraj, Lo, Walkiewicz, Anaka, Woods, Tan, Behren, Cebon, McKeown: Identifying and targeting determinants of melanoma cellular invasion. in Oncotarget 2016
the crucial role of Netrin-4 in blood vessel formation and the involvement of protein kinases activation in Netrin-4-induced biological effects related to vascular development.
netrin 4 is detected only at very low levels during early development
NTN4 is reduced in breast cancer tissues and NTN4 is associated with breast cancer cell migration and invasion via regulation of epithelial mesenchymal transition (EMT (show ITK Antibodies))-related biomarkers.
We found statistically significant association with AAO for three genes (WRN (show RECQL2 Antibodies), NTN4 and LAMC3 (show LAMC3 Antibodies)) with common associated variants.
Ntn4 promotes the proliferation and motility of gastric cancer cells which is mediated by its receptor Neo and through further activation of multi-oncogenic pathways
Increased expression of miR (show MLXIP Antibodies)-20a may play an important role in the pathogenesis of ovarian endometriosis by suppressing NTN4 expression.
Increased maternal netrin-4 levels in IUGR neonates may reflect in utero hypoxia, while the negative correlations between fetal netrin-1 (show NTN1 Antibodies) and -4 levels may exert the dynamic balance between their angio- and anti-angiogenic properties.
NTN4 acts as a positive regulator for TC axon branching through activity-dependent expression
NETRIN-4 protects glioblastoma cells FROM temozolomide induced senescence.
NTN4 expression was downregulated in cervical cancer tissues compared to normal controls, and in vivo mRNA level of NTN4 inversely correlated with miR (show MLXIP Antibodies)-196a expression.
GWAS study found two new SNPs associated with nickel dermatitis; SNPs are located in the NTN4 and PELI1 (show PELI1 Antibodies) genes
pattern of distribution suggests that a functional netrin-4-neogenin (show NEO1 Antibodies) pathway might be restricted to syncytiotrophoblasts, mesenchymal cells, and villous endothelial cells
Netrin-4 acted as an antiangiogenic factor in the cornea, with which the healthy cornea is enriched via its expression by corneal epithelial cells.
Our results indicate a role for netrin-4 as an angiogenesis modulating factor in O2-dependent vascular homeostasis while being less important during normal retinal developmental angiogenesis or during inflammatory neovascularization.
These results indicate that netrin-4 shed new light on its potential roles in treatmenting for angiogenic diseases that affect the ocular surface, as well as other tissues
Vascular endothelial cells interact with bone in suppressing bone through netrin-4.
Loss of Netrin-4 is associated with metastatic colorectal tumor progression.
The alpha6beta1 integrin is a netrin-4 receptor in endothelial cells.
NT-4 (show NTF4 Antibodies) overexpression decreases tumor growth and carcinomatosis, probably via an antiangiogenic effect
In vivo, Netrin-4 induces growth of lymphatic and blood vessels in the skin of transgenic mice.
netrin-4 is a component of basement membranes and is integrated into the laminin polymer via interactions with the laminin gamma1 andgamma3 short arms.
Netrin-4 significantly reduced pathological angiogenesis in Matrigel and laser-induced choroidal neovascularization models. Netrin-4, neogenin (show NEO1 Antibodies), and Unc5B (show UNC5B Antibodies) receptor expression was up-regulated in choroidal neovessel EC after laser injury
NTN4 belongs to a family of proteins related to laminins (see LAMA1, MIM 150320) Koch et al. (2000)
, hepar-derived netrin-like protein