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anti-Neurexin 1 (NRXN1) Antibodies

Neurexins function in the vertebrate nervous system as cell adhesion molecules and receptors. Additionally we are shipping Neurexin 1 Proteins (11) and Neurexin 1 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NRXN1 60391 Q63372
NRXN1 9378 Q9ULB1 , P58400
NRXN1 18189 Q9CS84
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Top anti-Neurexin 1 Antibodies at

Showing 10 out of 65 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN190771 (0.05µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
Dog Mouse Un-conjugated IF, WB Western blot analysis of Neurexin I on a P19 (murine embryonal carcinoma) lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the anti- Neurexin I antibody. 50 μg Log in to see 5 to 6 Days
Dog Goat Un-conjugated EIA, WB HEK293 lysate (10 µg protein in RIPA buffer) overexpressing Human NRXN1 with DYKDDDDK tag probed with ABIN783000 (0.5 µg/ml) in Lane A and probed with anti- DYKDDDDK Tag (1/3000) in lane C. Mock-transfected HEK293 probed with ABIN783000 (1 mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence 0.1 mg Log in to see 6 to 8 Days
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from Jurkat cells, using NRXN1 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-Neurexin 1 Polyclonal Antibody, Unconjugated (ABIN1386379) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cells, using NRXN1 antibody. 100 μL Log in to see 14 Days
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 14 Days
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days

NRXN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Neurexin 1 Antibodies

  1. Dog (Canine) Monoclonal NRXN1 Primary Antibody for IF, WB - ABIN968695 : Fallon, Moreau, Croft, Labib, Gu, Fon: Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain. in The Journal of biological chemistry 2002 (PubMed)
    Show all 5 references for ABIN968695

  2. Human Polyclonal NRXN1 Primary Antibody for ELISA, WB - ABIN564046 : Samuels, Hsueh, Shu, Liang, Tseng, Hong, Su, Volker, Neve, Yue, Tsai: Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK. in Neuron 2007 (PubMed)
    Show all 2 references for ABIN564046

  3. Human Polyclonal NRXN1 Primary Antibody for ELISA, WB - ABIN190771 : Feng, Schroer, Yan, Song, Yang, Bockholt, Cook, Skinner, Schwartz, Sommer: High frequency of neurexin 1beta signal peptide structural variants in patients with autism. in Neuroscience letters 2006 (PubMed)

More Antibodies against Neurexin 1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Neurexin 1 (NRXN1) interaction partners

  1. DNRX was expressed preferentially in central and motor neurons in embryos, larvae and adults, but not in glial cells. DNRX was expressed in pre- and post-synaptic areas in third instar larvae neuromuscular junctions.

  2. presynaptic spinophilin (show PPP1R9B Antibodies) fine-tunes neurexin/neuroligin signalling to control active zone number and functionality

  3. The intracellular region of NRX interacts with N-ethylmaleimide-sensitive factor (show NSF Antibodies). This interaction regulates short term synaptic depression.

  4. cooperation between Syd-1 (show SYD-1 Antibodies) and Nrx-1 seems to orchestrate early assembly processes between pre- and postsynaptic membranes

  5. Neurexin-1 null mutants exhibit associative learning defect in larvad.

  6. DNRX is essential for synaptic vesicle cycling, which plays critical roles in neurotransmission at neuromuscular junctions (NMJ).

Human Neurexin 1 (NRXN1) interaction partners

  1. Results demonstrate that NRXN1 alternative isoform expression is temporally regulated during critical periods of human neocortical development and identify potential differential molecular contributions of NRXN1-alpha and -beta to schizophrenia and bipolar disorder

  2. the top-ranked discordances were subsequently selected for validation by quantitative polymerase chain reaction (qPCR), from which one single ~120kb deletion in NRXN1 on chromosome 2 (bp 51017111-51136802) was validated

  3. Atypical hand-foot-genital syndrome and developmental delay due to de novo mutations in HOXA13 (show HOXA13 Antibodies) and NRXN1

  4. The rare variants in NRXN1 were significantly associated with smoking status.

  5. NRXN1 has an affinity for binding to LRRTM2 (show LRRTM2 Antibodies) in hippocampal synapses.

  6. heterozygous inactivation of NRXN1 directly impairs synaptic function in human neurons.

  7. Increasing expression of TGF-beta1 (show TGFB1 Antibodies) protein, decreasing expressions of Ghrelin (show GHRL Antibodies), Neurexin, and Neuroligin proteins can induce the loss or dysfunction of ganglion cells in distal intestinal canal

  8. Results indicate that the neurexin and neuroligin synaptic complex is intrinsically involved in the regulation of DISC1 (show DISC1 Antibodies) function, thus contributing to a better understanding of the pathology of schizophrenia.

  9. Study suggests a role of rare missense variants at NRXN1 and AKAP9 (show AKAP9 Antibodies) in schizophrenia susceptibility, probably related to alteration of the excitatory/inhibitory synaptic balance, deserving further investigation

  10. The phenotype found in the microdeletions of alpha exons of the NRXN1 gene is clearly distinguishable from the one found in the microdeletions of beta exons, with macrocephaly, epilepsy and mental retardation.

Cow (Bovine) Neurexin 1 (NRXN1) interaction partners

  1. The structure of neurexin 1alpha reveals features promoting a role as synaptic organizer

  2. The crystal structure of the alpha-neurexin-1 extracellular region reveals a hinge point for mediating synaptic adhesion and function

  3. crystallographic analysis of the second LNS/LG domain from neurexin 1alpha

Mouse (Murine) Neurexin 1 (NRXN1) interaction partners

  1. Findings demonstrate that the heterozygous loss of alpha-neurexin I and alpha-neurexin II (show NRXN2 Antibodies) in mice leads to phenotypes relevant to autism and schizophrenia

  2. Study shows that astrocyte-secreted hevin is a trans-synaptic linker that bridges presynaptic NRX1alpha with postsynaptic NL1B. This way, hevin organizes both pre- and postsynaptic specializations and aligns them across the synapse.

  3. Nlgn3 (show NLGN3 Antibodies) and Nrxn1 are differentially expressed in cerebral cortex and hippocampus which might be responsible for alterations in synaptic plasticity during agine.

  4. Thus our data suggest that perinatal exposure to BPA (show DST Antibodies) impairs spatial memory through upregulation of expression of synaptic proteins Nrxn1 and Nlgn3 (show NLGN3 Antibodies) and increased dendritic spine density in cerebral cortex and hippocampus of postnatal male mice.

  5. Mutant neurexin-1beta expression in mouse adult brain leads to core autism symptoms.

  6. neurexin 1 interaction with multi-PDZ domain protein (show INADL Antibodies) MUPP1 (show MPDZ Antibodies)

  7. Deletions within NRXN1 found in patients may be responsible for the impairments seen in social behaviours and Nrxn1alpha knockout mice are a useful model of human neurodevelopmental disorders.

  8. Nrxn1 and Nlgn (show NLGN4X Antibodies) genes that may represent an important aspect of their function at synapses in health and disease

  9. Cross-species co-expression and protein interaction network analyses identify glycogen synthase kinase 3 beta (GSK3B (show GSK3b Antibodies)) as one of the most consistent and conserved covariates of NRXN1.

  10. Parallel fiber protrusion triggered by neurexin signaling promotes bidirectional maturation of parallel fiber-Purkinje cell synapses by positive feedback.

Neurexin 1 (NRXN1) Antigen Profile

Protein Summary

Neurexins function in the vertebrate nervous system as cell adhesion molecules and receptors. Two neurexin genes are among the largest known in human (NRXN1 and NRXN3). By using alternate promoters, splice sites and exons, predictions of hundreds or even thousands of distinct mRNAs have been made. Most transcripts use the upstream promoter and encode alpha-neurexin isoforms\; fewer transcripts are produced from the downstream promoter and encode beta-neurexin isoforms. Alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and they interact with neurexophilins. Beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. The RefSeq Project has decided to create only a few representative transcript variants of the multitude that are possible.

Gene names and symbols associated with anti-Neurexin 1 (NRXN1) Antibodies

  • neurexin 1 (NRXN1) antibody
  • Neurexin 1 (Nrx-1) antibody
  • neurexin 1 (Nrx-1) antibody
  • neurexin 1 (nrxn1) antibody
  • neurexin 1 (Nrxn1) antibody
  • neurexin I (Nrxn1) antibody
  • 1700062G21Rik antibody
  • 9330127H16Rik antibody
  • A230068P09Rik antibody
  • CG7050 antibody
  • CT21808 antibody
  • Dmel\\CG7050 antibody
  • dnrx antibody
  • dnrx-1 antibody
  • GB13455 antibody
  • GB18754 antibody
  • Hs.22998 antibody
  • mKIAA0578 antibody
  • nrx antibody
  • Nrx-1 antibody
  • Nrx1 antibody
  • NRXN1 antibody
  • Nrxn1b antibody
  • PTHSL2 antibody
  • SCZD17 antibody

Protein level used designations for anti-Neurexin 1 (NRXN1) Antibodies

CG7050-PA , CG7050-PB , CG7050-PC , CG7050-PD , CG7050-PE , CG7050-PF , CG7050-PG , CG7050-PH , Neurexin-1 , Neurexin-like , Nrx-1-PA , Nrx-1-PB , Nrx-1-PC , Nrx-1-PD , Nrx-1-PE , Nrx-1-PF , Nrx-1-PG , Nrx-1-PH , drosophila neurexin , neurexin , neurexin 1 , neurexin 1 alpha , neurexin 1 beta , neurexin-1-beta isoform alpha1 , neurexin-1-beta isoform alpha2 , neurexin I-like , neurexin-1-alpha-like , neurexin I-alpha , neurexin I-beta , neurexin-1-alpha , neurexin-1-beta , non-processed neurexin I-alpha , neurexin I , neurexin-1 , neurexin I alpha , alpha-latrotoxin receptor (calcium-dependent)

781054 Sus scrofa
42646 Drosophila melanogaster
459224 Pan troglodytes
619185 Macaca mulatta
724217 Apis mellifera
100052908 Equus caballus
100127647 Xenopus (Silurana) tropicalis
100349063 Oryctolagus cuniculus
100466581 Ailuropoda melanoleuca
100567183 Anolis carolinensis
60391 Rattus norvegicus
9378 Homo sapiens
474589 Canis lupus familiaris
281950 Bos taurus
395398 Gallus gallus
100622083 Sus scrofa
18189 Mus musculus
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