Neurofilament, Light Polypeptide (NEFL) ELISA Kits

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Additionally we are shipping Neurofilament, Light Polypeptide Antibodies (226) and Neurofilament, Light Polypeptide Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
NEFL 18039 P08551
NEFL 4747 P07196
NEFL 83613 P19527
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Top Neurofilament, Light Polypeptide ELISA Kits at

Showing 8 out of 38 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 6.5 pg/mL 15.6-1000 pg/mL 96 Tests Log in to see 13 to 16 Days
Pig 7.81 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
Mouse 6.5 pg/mL 15.6-1000 pg/mL 96 Tests Log in to see 13 to 16 Days
Rat 1.95 pg/mL 7.8-500 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
Rabbit 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
Monkey 18.75 pg/mL 31.25-2000 pg/mL   96 Tests Log in to see 12 to 14 Days
Chicken 37.5 pg/mL 62.5-4000 pg/mL   96 Tests Log in to see 12 to 14 Days
  96 Tests Log in to see 15 to 18 Days

Top referenced Neurofilament, Light Polypeptide ELISA Kits

  1. Human NEFL ELISA Kit for Sandwich ELISA - ABIN419690 : Iłżecki, Iłżecka, Przywara, Terlecki, Grabarska, Stepulak, Zubilewicz: Effect of carotid endarterectomy on brain damage markers. in Acta neurologica Scandinavica 2016 (PubMed)

More ELISA Kits for Neurofilament, Light Polypeptide Interaction Partners

Mouse (Murine) Neurofilament, Light Polypeptide (NEFL) interaction partners

  1. Nefl(N98S/+) mice had a noticeable tremor, and most animals showed a hindlimb clasping similar to human Charcot-Marie-Tooth Type 2E phenotype.

  2. The finding of this study suggested that a lack of NFL protein alters the expression of cytoskeletal proteins and disrupts other NF subunits, causing intracellular aggregation but not gross structural changes in cortical neurons or cytoarchitecture.

  3. Neurofilament light chain (NFL) and neuronal intermediate filament protein (show GFAP ELISA Kits) alpha-internexin (show INA ELISA Kits) accumulate in axon swellings in the spinal white matter in a superoxide dismutase (SOD)-1 (show SOD1 ELISA Kits) mouse model.

  4. Data suggest that tetrahydropapaveroline (an endogenous catechol) causes oxidative stress resulting in astrocyte/neuronal cell death via generation of reactive oxygen species and modification/aggregation of NF-L (as in neurodegenerative diseases).

  5. Data show that mitochondria essentially stopped moving in neurons expressing neurofilament protein (NFL) mutants, probably a consequence of cytoskeletal disruption.

  6. Myo (show SYNPO2 ELISA Kits) Va interactions with intermediate filament proteins may serve similar roles in organizing organelle topography in different cell types.

  7. NEFL transgenic mice exhibited extended duration of the hindlimb clasping response and gait anomalies, as well as sensorimotor deficits in stationary beam and suspended bar tests

  8. Neuropathic effects of overexpressing NF-L can occur at the level of transgene RNA and are mediated by sequences in the NF-L 3' UTR (show UTS2R ELISA Kits)

  9. nNOS (show NOS1 ELISA Kits) inhibitor, AR-R17477AR, prevents the loss of NF68 immunoreactivity induced by methamphetamine in the mouse striatum

  10. The 3' untranslated region of light neurofilament (NF-L) transcript enhances the reactivity of its own translated product and leads to loss of solubility and aggregation of NF-L protein and to coaggregation of mutant superoxide dismutase 1 (SOD1 (show SOD1 ELISA Kits)) protein

Human Neurofilament, Light Polypeptide (NEFL) interaction partners

  1. Results provide evidence that in particular pNfH can be used as a good diagnostic biomarker of ALS (show IGFALS ELISA Kits) at the diagnostic stage. Moreover, results indicate that NfL may be useful in monitoring disease progression in a subset of patients.

  2. Level of neurofilament heavy chain and light chains were significantly elevated in the cerebrospinal fluid of Amyotrophic Lateral Sclerosis (ALS) patients compared to healthy controls/controls without parenchymal central nervous system involvement and ALS mimic disease patients.

  3. Results from 2 independent prospective cohort studies show that serum NFL is a sensitive and dynamic biomarker for axonal injury in concussive traumatic brain injury. The marker should be useful to detect and monitor CNS injury in concussion

  4. Findings support the potential value of serum NfL as a marker of neuroaxonal injury in early multiple sclerosis. Its reduction over time could represent regression to the mean, or a possible treatment effect of IFN-beta (show IFNB1 ELISA Kits)-1a. Association with whole brain atrophy and formation of acute white matter lesions has implications to use serum NfL as a biomarker of the overall consequences of brain damage and ongoing disease acti...

  5. Higher serum NfL concentrations are associated with more rapid brain atrophy and may therefore reflect disease intensity in dementia (FTD (show FTL ELISA Kits)). Because blood sampling is less invasive and has better patient acceptability than lumbar puncture, serum NfL may provide important prognostic information and prove to be a useful outcome measure for clinical trials in FTD (show FTL ELISA Kits).

  6. We conclude that the NEFL N98S mutation is associated with a dominant intermediate Charcot-Marie-Tooth disease phenotype characterized by early-onset sensorimotor neuropathy delaying motor milestones, which may evolve into a severe and complex clinical picture including cerebellar ataxia (show USP14 ELISA Kits).

  7. Plasma Concentration of the Neurofilament Light Protein (NFL) is a Biomarker of CNS Injury in HIV Infection

  8. The results showed an important role for miR (show MLXIP ELISA Kits)-25 in regulating NEFL expression in Glioblastoma multiforme.

  9. Finally, we demonstrated that NEFL inhibited the NF-kappaB (show NFKB1 ELISA Kits) pathway, thereby suppressing the expression of uPA (show PRAP1 ELISA Kits) and decreasing NSCLC invasiveness and migration.

  10. Cerebrospinal fluid NFL concentration is increased by the early clinical stage of Alzheimer's Disease.

Neurofilament, Light Polypeptide (NEFL) Antigen Profile

Antigen Summary

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

Gene names and symbols associated with NEFL

  • neurofilament, light polypeptide (NEFL) antibody
  • neurofilament, light polypeptide b (neflb) antibody
  • neurofilament, light polypeptide (Nefl) antibody
  • neurofilament, light polypeptide (nefl) antibody
  • AI847934 antibody
  • CMT1F antibody
  • CMT2E antibody
  • nefl antibody
  • NF-L antibody
  • NF68 antibody
  • NFL antibody
  • XNF-L antibody
  • zgc:136626 antibody

Protein level used designations for NEFL

neurofilament, light polypeptide 68kDa , neurofilament, light polypeptide , neurofilament light polypeptide , 68 kDa neurofilament protein , neurofilament protein L , neurofilament triplet L protein , light molecular weight neurofilament protein , neurofilament protein, light chain , neurofilament subunit NF-L , NF-L , micro glutamic acid-rich protein , neurofilament protein , Neurofilament triplet L protein

464063 Pan troglodytes
477378 Canis lupus familiaris
641444 Macaca mulatta
664698 Danio rerio
18039 Mus musculus
4747 Homo sapiens
83613 Rattus norvegicus
281348 Bos taurus
100521224 Sus scrofa
397822 Xenopus laevis
419528 Gallus gallus
100173482 Pongo abelii
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