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Neuropeptide Y Receptor Y2 Proteins (NPY2R)

Receptor for neuropeptide Y and peptide YY. Additionally we are shipping NPY2R Antibodies (89) and NPY2R Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NPY2R 4887 P49146
NPY2R 18167 P97295
Rat NPY2R NPY2R 66024  
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Top NPY2R Proteins at

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days

NPY2R Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

More Proteins for Neuropeptide Y Receptor Y2 (NPY2R) Interaction Partners

Human Neuropeptide Y Receptor Y2 (NPY2R) interaction partners

  1. polymorphisms in the NPY2R gene may be useful in identifying women at risk for osteoporosis.

  2. The C-terminal alpha-helix of Neuropeptide Y (show NPY Proteins), which is formed in a membrane environment in the absence of the receptor, is unwound starting at T(32) to provide optimal contacts in a binding pocket within the transmembrane bundle of the NPY-Y2 receptor.

  3. Data show that the Y2-receptor high expression G allele is associated with a less efficient mode of action cascading where different task goals are activated in parallel.

  4. The molecular mobility of the human neuropeptide Y receptor type 2 reconstituted into dimyristoylphosphatidylcholine (DMPC) membranes was investigated by means of solid-state NMR spectroscopy.

  5. The results of this study provide evidence that the functionally relevant single nucleotide polymorphism (SNP) in the NPY2R promoter gene affect circumscribed processes of early sensory processing

  6. Data indicate modest association of the age at onset (AO) with two neuropeptide Y (NPY (show NPY Proteins)) promoter variations and a highly significant association with NPY (show NPY Proteins) receptor NPY2R promoter single nucleotide polymorphism (SNP rs2234759).

  7. This study reviews neuropeptide Y2 receptor modulators (mainly non-peptidic antagonists) and their structure-activity relationships.

  8. this study concludes that common genetic variation in the proximal NPY2R promoter influences transcription factor binding so as to alter gene expression in neuroendocrine cells, and consequently cardiometabolic traits in humans.

  9. we determined the role of the C-terminus in the anterograde transport of the human neuropeptide Y (show NPY Proteins) receptor (hYR) type 2

  10. Surface masking of the Y2 receptor could to a degree reflect restricted access of the large (34-36-residue) physiological agonists.

Mouse (Murine) Neuropeptide Y Receptor Y2 (NPY2R) interaction partners

  1. confirms the critical role of Y2 signalling to control neuropeptide Y (show NPY Proteins) and associated pro-opiomelanocortin (show POMC Proteins) expression in the arcuate nuclei

  2. Study shows that NPY (show NPY Proteins) inhibits fear learning and promotes cued extinction by reducing fear expression also via activation of presynaptic Y2 receptors on central amygdala neurons

  3. Study shows pronounced adaptive changes in the mouse hippocampus both with regard to NPY (show NPY Proteins) synthesis and NPY (show NPY Proteins) receptor synthesis and binding, which may contribute to regulating neuronal seizure susceptibility after kainate

  4. an integrated neural circuit modulates growth hormone (show GH1 Proteins) release relative to food intake; data provide essential information to address the differential roles of Y1 and Y2 receptors in regulating the release of GH under fed and fasting states

  5. Our results showed the altered expression of NPY (show NPY Proteins), Y1R (show NPY1R Proteins) and Y2R but not Y5R (show NPY5R Proteins) in hippocampus and temporal lobe cortex of tremor rat brain.

  6. Data from knockout (KO) mice suggest roles for neuropeptide Y (NPY (show NPY Proteins)) and NPY2 receptors in fear acquisition/fear stimulus discrimination. Npy1r (show NPY1R Proteins)/Npy2r double KO mice display excessive recall of conditioned fear/impaired fear extinction.

  7. NPY (show NPY Proteins) Y2 receptors control the level of hyperactive behavior under conditions of limited food access.

  8. Peripheral Y2 receptor signaling is critical in the regulation of oxidative fuel selection and physical activity and protects against high-fat diet-induced obesity.

  9. Data show that Y2R is mostly presynaptic, coexists with NPY (show NPY Proteins) and NPY (show NPY Proteins) Y1R (show NPY1R Proteins), and suggest that Y2Rs thus have a modulatory role in mediating presynaptic neurotransmitter release.

  10. NPY-Y2 receptor exerts a direct control over both the tonic and phasic release of dopamine

Rabbit Neuropeptide Y Receptor Y2 (NPY2R) interaction partners

  1. Results suggest that rabbit and human Y1, Y2 and Y5 receptor (show NPY5R Proteins) subtypes are well conserved, whereas Y4 receptors are less well conserved.

Rhesus Monkey Neuropeptide Y Receptor Y2 (NPY2R) interaction partners

  1. Lower mRNA levels of neuropeptide Y (show NPY Proteins) receptor 1 (NPY1R (show NPY1R Proteins)) and NPY5R (show NPY5R Proteins) but not NPY (show NPY Proteins) or NPY2R in the central nucleus of the amygdala predicted elevated anxious temperament.

NPY2R Protein Profile

Protein Summary

Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > PYY and NPY free acid.

Gene names and symbols associated with NPY2R

  • neuropeptide Y receptor Y2 (Npy2r)
  • neuropeptide Y receptor 2 (npy2r)
  • neuropeptide Y receptor Y2 (npy2r)
  • neuropeptide Y receptor Y2 (NPY2R)
  • NPY-Y2 protein
  • NPY2-R protein
  • npy2r protein
  • si:dkey-30k22.9 protein

Protein level used designations for NPY2R

neuropeptide Y receptor Y2 , neuropeptide Y receptor type 2 , neuropeptide Y receptor 2 , neuropeptide Y receptor type 2-like , NPY-Y2 receptor , Y2 receptor , neuropeptide Y receptor Y2-like , neuropeptide Y-Y2 receptor , neuropeptide Y/peptide YY-Y2 receptor , NPY2-R , neuropeptide Y Y2 receptor , Neuropeptide Y receptor type 2 , gastric Y2 receptor

100135581 Cavia porcellus
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613241 Danio rerio
100062115 Equus caballus
100481862 Ailuropoda melanoleuca
100580555 Nomascus leucogenys
4887 Homo sapiens
18167 Mus musculus
66024 Rattus norvegicus
482661 Canis lupus familiaris
397291 Sus scrofa
281943 Bos taurus
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100728839 Cavia porcellus
443368 Ovis aries
100008937 Oryctolagus cuniculus
461562 Pan troglodytes
574149 Macaca mulatta
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