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Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) ELISA Kits

NFE2L2 encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. Additionally we are shipping NRF2 Antibodies (169) and NRF2 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
NFE2L2 4780 Q16236
NFE2L2 18024 Q60795
NFE2L2 83619 O54968
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Top NRF2 ELISA Kits at

Showing 10 out of 33 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Rat 0.058 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 9 to 11 Days
Mouse 5.7 pg/mL 15.62-1000 pg/mL 96 Tests Log in to see 9 to 11 Days
Human 0.057 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 9 to 11 Days
  96 Tests Log in to see 2 to 3 Days
  96 Tests Log in to see 11 to 13 Days
  96 Tests Log in to see 11 to 13 Days
Guinea Pig
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More ELISA Kits for NRF2 Interaction Partners

Zebrafish Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. Bach1 (show BACH1 ELISA Kits) regulates the liver specificity and transience of the Nrf2a-dependent induction of hmox1a and that heme mediates this regulation through Bach1 (show BACH1 ELISA Kits) inhibition based on its level in each tissue.

  2. The Bach1b-MafK heterodimer represses the zymogen promoters, whereas the Nrf2a-MafK heterodimer activates them.

  3. The expression of nrf (show NRF1 ELISA Kits) genes varies temporally throughout development and nrf (show NRF1 ELISA Kits) genes are induced following a pro-oxidant exposure and are potentially cross-regulated by gene family members Nrf2a and Nrf2b (show GABPb ELISA Kits).

  4. oxidative stress is an important mechanism of Cd-mediated injury in the zebrafish olfactory system; the Nrf2 pathway plays a protective role against cellular oxidative damage and is important in maintaining zebrafish olfactory function.

  5. results revealed that nrf2 mutant zebrafish are viable and fertile but show an increased susceptibility to oxidative stress and electrophiles

  6. compared the tissue-specific expression of several Nrf2 target genes in zebrafish larvae; Tissue-restricted induction was observed in the nose, gill, and/or liver for seven genes in response to Nrf2-activating compounds

  7. Nrf2 is protective against PFOS-induced oxidative stress in zebrafish larvae.

  8. mutation of either residual cysteine residue in Keap1a (show KEAP1 ELISA Kits) and Keap1b disrupted the ability of Keap1 (show KEAP1 ELISA Kits) to repress Nrf2, indicating that the presence of either Cys (show DNAJC5 ELISA Kits)-273 or Cys (show DNAJC5 ELISA Kits)-288 is sufficient for fish Keap1 (show KEAP1 ELISA Kits) molecules to fully function

  9. study reports that the Keap1 (show KEAP1 ELISA Kits)-Nrf2 system comprises discrete sensor sites, including the Keap1 (show KEAP1 ELISA Kits) cysteines Cys (show DNAJC5 ELISA Kits)-151 and Cys (show DNAJC5 ELISA Kits)-273, for a variety of Nrf2-activating compounds

  10. findings demonstrate that antioxidant responses are a component of polycyclic aromatic hydrocarbon (PAH)synergistic developmental toxicity and that NRF2 is protective against prooxidant and PAH challenges during development

Cow (Bovine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. These findings suggest that bronchiolar epithelial cells and macrophages up-regulate Nrf2 expression early in the course of infection, which results in increased expression of HO-1 (show HMOX1 ELISA Kits) within these cells.

  2. the survival and developmental competence of embryos cultured under oxidative stress are associated with activity of the NRF2-mediated oxidative stress response pathway during bovine pre-implantation embryo development.

  3. investigation of molecular mechanisms of microvascular complications in diabetes/hyperglycemia: Nrf2 is involved in regulation of HO-1 (show HMOX1 ELISA Kits) gene expression in aortic endothelial cells by advanced glycation end products

Pig (Porcine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. The effects of ochratoxin A on the nuclear translocation and transactivation of the transcription factor Nrf2 as well as mRNA levels of Nrf2 target genes are reported.

Human Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. Both Nrf2 (show GABPA ELISA Kits) and NF-kappaB (show NFKB1 ELISA Kits) signaling may be pivotal in the regulation of drug-induced liver injury. NF-kappaB (show NFKB1 ELISA Kits)-inhibiting effects that coincide with a strong Nrf2 (show GABPA ELISA Kits) stress response likely sensitize liver cells to pro-apoptotic signaling cascades induced by intrinsic cytotoxic pro-inflammatory cytokines.

  2. A marked (show GABPA ELISA Kits) increase in Nrf2 expression was detected in the leukocytes obtained from the Hemorrhagic shock patients, which indicates a correlation between Nrf (show MPO ELISA Kits)2 expression and the development of Hemorrhagic shock.

  3. Glioma patients with high Nrf2 (show GABPA ELISA Kits) brain expression had shorter overall survival than those with low levels.

  4. stress. Our combined data revealed a protective role of miR (show MLXIP ELISA Kits)-214 signaling in erythroid cells against oxidative stress, and also shed new light on Nrf2 (show GABPA ELISA Kits)-mediated cytoprotective machinery.

  5. TGF-beta (show TGFB1 ELISA Kits) and hypoxia/reoxygenation promoted tumor progression and radioresistance of A549 cells through reactive oxygen species-mediated activation of Nrf2 (show GABPA ELISA Kits) and EGFR (show EGFR ELISA Kits).

  6. Inhibition of NRF2 (show GABPA ELISA Kits) by KEAP1 (show KEAP1 ELISA Kits) overexpression compromises metabolic reprogramming of fibroblasts and results in reduced efficiency of induced pluripotent stem cells colony formation.

  7. Phycocyanin prevented mitochondrial-dependent apoptosis in methylglyoxal induced INS-1 (show FOXM1 ELISA Kits) cells and the effect was associated with Nrf2 (show GABPA ELISA Kits) activation.

  8. Results suggest that NRF2 (show GABPA ELISA Kits) plays an important role in regulating p53 (show TP53 ELISA Kits) and SIRT1 (show SIRT1 ELISA Kits) to maintain MSC (show MSC ELISA Kits) stemness.

  9. Nrf2 (show GABPA ELISA Kits) being elevated in early precursor lesions counteracts the growth inhibiting function of TGF-beta1 (show TGFB1 ELISA Kits) already in benign and premalignant pancreatic ductal epithelial cells.

  10. antiangiogenic and anti-inflammatory activities of Hericium erinaceus may contribute to its anticancer property through inhibition of TNF-alpha (show TNF ELISA Kits) and modulation of MMP-9 (show MMP9 ELISA Kits)/NF-kappaB (show NFKB1 ELISA Kits) and Nrf2 (show GABPA ELISA Kits)-antioxidant signaling pathways

Mouse (Murine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) interaction partners

  1. Nrf2 deficiency increased susceptibility to oxidative stress-induced (show SQSTM1 ELISA Kits) small intestinal carcinogenesis in mice

  2. Is closely associated with upregulation of the Ref1 (show THOC4 ELISA Kits)/Nrf2 signalling pathway.

  3. SIRT1 (show SIRT1 ELISA Kits) promoted the stability of NRF2 by regulating the deacetylation and activation of the NRF2/ARE antioxidant pathway.

  4. The Nrf2-KO mice exhibited more severe lung and liver injury following hemorrhagic shock as evidenced by increased tissue damage, increased myeloperoxidase (show MPO ELISA Kits) activity and the increased production of pro-inflammatory cytokines. Additionally, Nrf2 deficiency augmented cytokine production induced by the exposure of peritoneal mouse macrophages to lipopolysaccharide following hemorrhagic shock.

  5. high NRF2 activity is advantageous for cochlear protection from noise-induced injury, and NRF2 is a promising target for NIHL prevention.

  6. These results suggest for the first time that FF prevents the development of diabetic nephropathy via up-regulating FGF21 (show FGF21 ELISA Kits) and stimulating PI3K/Akt (show AKT1 ELISA Kits)/GSK-3beta/Fyn (show FYN ELISA Kits)-mediated activation of the Nrf2 pathway.

  7. Our results show that epicatechin protects the TBI brain by activating the Nrf2 pathway, inhibiting heme oxygenase-1 protein expression, and reducing iron deposition The latter two effects could represent an Nrf2-independent mechanism in this model of TBI

  8. These results provide a new mechanism by which LXA4 inhibits LPS (show TLR4 ELISA Kits)-induced ALI through Nrf2-mediated E-cadherin (show CDH1 ELISA Kits) expression

  9. Caffeic acid induces Nrf2 activation by decreasing the expression of its inhibitor protein Keap1 (show KEAP1 ELISA Kits) and blocking the binding of Nrf2 with Keap1 (show KEAP1 ELISA Kits).

  10. Our observations that oral DMF treatment promoted immune modulation and provided equal clinical benefit in acute EAE in Nrf2(-/-) and WT mice, suggest that the antiinflammatory activity of DMF in treatment of MS patients may occur through alternative pathways, independent of Nrf2.

NRF2 (NFE2L2) Antigen Profile

Antigen Summary

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters\; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with NFE2L2

  • nuclear factor (erythroid-derived 2)-like 2a (nfe2l2a) antibody
  • nuclear factor (erythroid-derived 2)-like 2 (nfe2l2) antibody
  • nuclear factor (erythroid-derived 2)-like 2 (NFE2L2) antibody
  • nuclear factor, erythroid 2-like 2 (NFE2L2) antibody
  • nuclear factor, erythroid derived 2, like 2 (Nfe2l2) antibody
  • AI194320 antibody
  • NF-E2R2 antibody
  • nfe2l2 antibody
  • NRF2 antibody
  • wu:fc15g09 antibody
  • wu:fj67e03 antibody

Protein level used designations for NFE2L2

Nrf2a , nuclear factor (erythroid-derived 2)-like 2 , nuclear factor erythroid 2-related factor 2 , ECH , NF-E2-related factor 2 , NFE2-related factor 2 , nuclear factor, erythroid derived 2, like 2 , HEBP1 , nuclear factor erythroid-derived 2-like 2 , nrf2 , nuclear factor erythroid 2-like 2

360149 Danio rerio
444736 Xenopus laevis
396014 Gallus gallus
478813 Canis lupus familiaris
497024 Bos taurus
100516343 Sus scrofa
4780 Homo sapiens
18024 Mus musculus
83619 Rattus norvegicus
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