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OXA encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Additionally we are shipping Orexin A Antibodies (61) and Orexin A Proteins (3) and many more products for this protein.
Showing 10 out of 47 products:
Human OXA ELISA Kit for Sandwich ELISA - ABIN366574
Bilir, Engin, Can, Temi, Demirtas: The prognostic role of inflammation and hormones in patients with metastatic cancer with cachexia. in Medical oncology (Northwood, London, England) 2015
Histamine Transmission Modulates the Phenotype of Murine Narcolepsy Caused by Orexin (show OX ELISA Kits) Neuron Deficiency
observation that inhibition of the Orexin (show OX ELISA Kits)-1 receptor signaling blunted binge-like Ethanol, and saccharin drinking suggests that reward-related Orexin (show OX ELISA Kits) circuits participate in the consumption of salient reinforcers regardless of calories.
Results suggest that exercise produces antidepressant effects via suppression of Hcrt (show OX ELISA Kits)/Orx and melanin-concentrating hormone (show PMCH ELISA Kits) neural systems in the basolateral amygdala
Hcrt (show OX ELISA Kits) neuronal activity and Hcrt (show OX ELISA Kits)-mediated stress responses were inhibited by the satiety hormone leptin (show LEP ELISA Kits).
This study demonstrated that the GABAergic input property of orexin (show OX ELISA Kits) neurons responds rapidly to sleep deprivation.
sleep deprivation or increasing wakefulness by rescue of orexinergic neurons in APP (show APP ELISA Kits)/PS1 (show PSEN1 ELISA Kits) mice lacking orexin (show OX ELISA Kits) increased the amount of amyloid beta pathology in the brain.
orexin (show OX ELISA Kits) activates the mTOR (show FRAP1 ELISA Kits) pathway, a central regulator of cell growth and metabolism, in the mouse brain and cell lines that express GPCRs, OX1R (show HCRTR1 ELISA Kits), or OX2R (show CD200R1 ELISA Kits)
This study demonistrated that absence of the Hcrt (show OX ELISA Kits) peptide has gender-specific effects. In contrast, Hcrt (show OX ELISA Kits)-ataxin mice and human narcoleptics, with loss of the whole Hcrt (show OX ELISA Kits) cell, show weight gain in both sexes.
These results suggest that orexin (show OX ELISA Kits) neuronal activity plays a crucial role in the maintenance of wakefulness especially in the active phase in mice.
351 narcoleptic episodes of orexin (show OX ELISA Kits)-deficient mice were behaviorally characterized
The aim of the study was to determine by immunochemistry the expression of leptin (show LEP ELISA Kits), orexin A and orphanin FQ (show PNOC ELISA Kits) in the major salivary glands (parotid, submandibular and sublingual) of rat, sheep and cow.
first evidence for the expression of oxA and ox1R (show HCRTR1 ELISA Kits) in the vestibular glands of mammalian genital tract
The impact of the phase of the estrous cycle on the observed changes in plasma orexin (show OX ELISA Kits) levels in domestic pigs.
Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.
, orexin A
, orexin B
, Hypocretin (orexin) neuropeptide