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Ornithine Decarboxylase 1 Proteins (ODC1)

ODC1 encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. Additionally we are shipping Ornithine Decarboxylase 1 Antibodies (113) and Ornithine Decarboxylase 1 Kits (41) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ODC1 4953 P11926
ODC1 24609 P09057
ODC1 18263 P00860
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Top Ornithine Decarboxylase 1 Proteins at

Showing 10 out of 22 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
HOST_Escherichia coli (E. coli) Human GST tag Ornithine Decarboxylase 1 (ODC1) (AA 1-461), (full length) protein (GS... 1 mg Log in to see 56 to 66 Days
Yeast Nematode His tag   1 mg Log in to see 56 to 66 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
Yeast Caenorhabditis elegans His tag   1 mg Log in to see 56 to 66 Days
Yeast Trypanosoma brucei His tag   1 mg Log in to see 56 to 66 Days
Yeast Datura stramonium His tag   1 mg Log in to see 56 to 66 Days

ODC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Rat (Rattus)

Mouse (Murine)

More Proteins for Ornithine Decarboxylase 1 (ODC1) Interaction Partners

Zebrafish Ornithine Decarboxylase 1 (ODC1) interaction partners

  1. molecular cloning of species-specific enzyme and its antizyme-mediated degradation

Human Ornithine Decarboxylase 1 (ODC1) interaction partners

  1. mechanistic study of the molecular interactions between antizyme inhibitor and its interacting proteins CCND1 (show CCND1 Proteins) and ornithine decarboxylase

  2. We earlier presented evidence for a physical interaction between ODC and SPR (show SPR Proteins) and we showed that RNAi-mediated knockdown of SPR (show SPR Proteins) expression significantly reduced native ODC enzyme activity and impeded Neuroblastoma (show ARHGEF16 Proteins) cell proliferation.

  3. Bag-1 (show BAG1 Proteins) indirectly affects cell survival through c-Myc (show MYC Proteins) activated signalling that causes elevation of ornithine decarboxylase levels, leading to an increase of the polyamine content.

  4. High ODC expression is associated with Medulloblastoma.

  5. Data show the the interplay between the enzyme ornithine decarboxylase (ODC) and two regulatory proteins: antizyme (Az) and inhibitor (AzIN).

  6. Data suggest that down-regulation of ODC (using siRNA or pharmacologic inhibitor) in bone marrow-derived mesenchymal stem cells results in reduced intracellular polyamines (putrescine, spermidine, and spermine) and enhanced osteogenesis.

  7. tumor ornithine decarboxylase level heterogeneity increased with increasing tumor malignancy

  8. The results suggested that the ODC gene might act as a prognostic factor for breast cancer and it could be a promising therapeutic target.

  9. BTF3 (show BTF3 Proteins), HINT1 (show HINT1 Proteins), NDRG1 (show NDRG1 Proteins) and ODC1 protein over-expression in human prostate cancer tissue

  10. Akt (show AKT1 Proteins) activation by ODC+COX-2 over-expression.

Xenopus laevis Ornithine Decarboxylase 1 (ODC1) interaction partners

  1. Translation of ODC is therefore integral to cytoplasmic maturation, protecting metaphase II oocytes from reactive oxygen species-induced apoptosis.

Mouse (Murine) Ornithine Decarboxylase 1 (ODC1) interaction partners

  1. the Myc (show MYC Proteins)-ODC axis plays a critical role in the cellular transformation induced by myeloproliferative neoplasm-associated JAK2 (show JAK2 Proteins) V617F mutant

  2. Introduction of a fluorine atom at C3 of 3-deazauridine shifts its antimetabolic activity from inhibition of CTP synthetase to inhibition of orotidylate decarboxylase, an early event in the de novo pyrimidine nucleotide biosynthesis pathway.

  3. Androgens act via the AR to upregulate Odc1 in skeletal muscle myoblasts, and Odc1 promotes myoblast proliferation and delays differentiation.

  4. the immunosuppression promoted by increased epidermal ODC is mediated by a reduction in cytokine levels, which suppresses dendritic cell migration and reduces immune cell infiltration to the site of hapten application

  5. HuR (show ELAVL1 Proteins) plays a causative role in ODC up-regulation during nonmelanoma skin cancer development by binding to and stabilizing the ODC transcript.

  6. Overexpression of a dominant-negative ornithine decarboxylase in mouse skin: effect on enzyme activity and papilloma formation

  7. In B16-F1 cells HGF (show HGF Proteins) increased AP-1 (show JUN Proteins) activity and the mRNA expression of various AP-1 (show JUN Proteins) subunits. HGF (show HGF Proteins)-induced transcription of mouse ODC was largely due to triggering of AP-1 (show JUN Proteins) pathway.

  8. cell constituents required for mODC degradation are conserved between animals and fungi, and that both mammalian and fungal ODC are subject to proteasome-mediated proteolysis by ubiquitin-independent mechanisms

  9. The role of ODC in the Citrobacter rodentium model of colitis was studied. ODC was induced in the colon during the infection. Inhibition of ODC exacerbated the colitis.

  10. elevated ODC values found in the ovary of immature and adult mice play a relevant function in ovarian physiology

Ornithine Decarboxylase 1 (ODC1) Protein Profile

Protein Summary

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.

Gene names and symbols associated with ODC1

  • Ornithine decarboxylase 1 (Odc1)
  • ornithine decarboxylase 1 (odc1)
  • ornithine decarboxylase 1 (ODC1)
  • ornithine decarboxylase (odc)
  • Orn/DAP/Arg decarboxylase 2 domain-containing protein (odc)
  • Diaminopimelate decarboxylase (odc)
  • Ornithine decarboxylase (odc)
  • ornithine decarboxylase (ODC)
  • ornithine decarboxylase 1 (Odc1)
  • ornithine decarboxylase, structural 1 (Odc1)
  • Protein ODC-1 (odc-1)
  • CG8721 protein
  • CHUNP6922 protein
  • DDBDRAFT_0204020 protein
  • DDBDRAFT_0237755 protein
  • DDB_0204020 protein
  • DDB_0237755 protein
  • Dmel\\CG8721 protein
  • dodc1 protein
  • fc54f04 protein
  • fi06d08 protein
  • Odc protein
  • ODC1 protein
  • odc1-a protein
  • odc2 protein
  • wu:fc54f04 protein
  • wu:fi06d08 protein
  • xODC1 protein
  • xodc2 protein

Protein level used designations for ODC1

ornithine decarboxylase 1 , CG8721-PA , Odc1-PA , ornithine decarboxylase , group IV decarboxylase , Ornithine decarboxylase , Ornitine decarboxylase , ODC 1 , xODC1

35766 Drosophila melanogaster
114426 Danio rerio
448028 Xenopus (Silurana) tropicalis
459027 Pan troglodytes
553919 Lotus japonicus
695625 Macaca mulatta
2866337 Bartonella quintana str. Toulouse
3129917 Haloarcula marismortui ATCC 43049
4944153 Saccharopolyspora erythraea NRRL 2338
4995583 Aeromonas salmonicida subsp. salmonicida A449
5723008 Chlamydomonas reinhardtii
8622878 Dictyostelium discoideum AX4
9448557 Corynebacterium pseudotuberculosis FRC41
9700620 gamma proteobacterium HdN1
10843230 Corynebacterium ulcerans BR-AD22
100027936 Monodelphis domestica
100232922 Vitis vinifera
100303479 Saccoglossus kowalevskii
100404336 Callithrix jacchus
100435590 Pongo abelii
100463572 Ailuropoda melanoleuca
100567639 Anolis carolinensis
100581966 Nomascus leucogenys
414408 Sus scrofa
4953 Homo sapiens
24609 Rattus norvegicus
100717513 Cavia porcellus
281365 Bos taurus
421937 Gallus gallus
475666 Canis lupus familiaris
379859 Xenopus laevis
18263 Mus musculus
179079 Caenorhabditis elegans
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