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Paired Box 7 Proteins (PAX7)

PAX7 is a member of the paired box (PAX) family of transcription factors. Additionally we are shipping PAX7 Antibodies (213) and PAX7 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PAX7 5081 P23759
Rat PAX7 PAX7 500574  
PAX7 18509 P47239
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Top PAX7 Proteins at

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 59 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 59 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days

PAX7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

More Proteins for Paired Box 7 (PAX7) Interaction Partners

Pig (Porcine) Paired Box 7 (PAX7) interaction partners

  1. Porcine skeletal muscle-derived PW1(pos)/Pax7(neg) interstitial cells are a source of stem/progenitor cells.

  2. The total expression profile of MyoD (show MYOD1 Proteins) and Pax7 genes suggests that higher muscularity in Pietrain pigs is associated with the presence of a greater number of active satellite stem cells compared to other breeds.

  3. Pax7 might be one of the molecules involved in controlling the proliferation/differentiation ratio in the pool of satellite cells present in post-natal porcine skeletal muscles.

Turkey Paired Box 7 (PAX7) interaction partners

  1. These data suggested that expression of the myogenic regulatory transcription factors are dependent upon expression of glypican-1 (show GPC1 Proteins) and syndecan-4 (show SDC4 Proteins) during satellite cell proliferation and differentiation, and Pax7 expression is influenced by glypican-1 (show GPC1 Proteins).

Human Paired Box 7 (PAX7) interaction partners

  1. Our results on Pax7 and MyoD protein expression suggest that proliferation and differentiation of skeletal muscle stem cells are affected in ALS patients, and the myogenic processes cannot overcome the denervation-induced wasting.

  2. these results suggest that sarcoma metastasis can be partially controlled through Pax7/MyoD (show MYOD1 Proteins)-dependent activation of miR (show MLXIP Proteins)-182 and provide insight into the role that myogenic transcription factors have in sarcoma progression

  3. RAGE (show AGER Proteins) upregulates myogenin (show MYOG Proteins) which upregulates MyoD (show MYOD1 Proteins) and downregulates PAX7, with consequent inhibition of proliferation and stimulation of differentiation.

  4. Pax7 responds to NF-kappaB (show NFKB1 Proteins) by impairing the regenerative capacity of myogenic cells in the muscle microenvironment to drive muscle wasting in cancer.

  5. High prevalence of 1p36 microdeletions in B-cell non-Hodgkin lymphomas is associated with PAX7 loss.

  6. Our study replicated previous GWAS findings for markers in VAX1 (show VAX1 Proteins) in the Asian population, and identified rare variants in PAX7 and VAX1 (show VAX1 Proteins) that may contribute to the etiology of CL(P)

  7. In addition, eight genes classified as 'second tier' hits in the original study (PAX7, THADA, COL8A1 (show COL8A1 Proteins)/FILIP1L, DCAF4L2, GADD45G (show GADD45G Proteins), NTN1 (show NTN1 Proteins), RBFOX3 (show RBFOX3 Proteins) and FOXE1 (show FOXE1 Proteins)) showed evidence of linkage and association in this replication sample.

  8. SUMOylation of Pax7 is essential for neural crest development in chick embryos and for the inhibitory roles of Pax7 in C2C12-muscle differentiation.

  9. PAX3 (show PAX3 Proteins)/7-FKHR (show FOXO1 Proteins) gene fusions expression was detected in 56% of ARMS tumor samples.

  10. Detection of PAX3 (show PAX3 Proteins)/PAX7-FKHR (show FOXO1 Proteins) fusion transcripts is a novel tool for Rhabdomyosarcoma diagnosis

Xenopus laevis Paired Box 7 (PAX7) interaction partners

  1. Our results show that the expression of Pax6 (show PAX6 Proteins) and Pax7 is widely maintained in the adult brain of Xenopus

  2. The Pax3 (show PAX3 Proteins) and Pax7 paralogs cooperate in neural and neural crest patterning using distinct molecular mechanisms, in Xenopus laevis embryos.

  3. Results show that inhibition of pax7 does not prevent differentiation of satellite cells to myofibres, but it does prevent their maintenance as a stem cell population.

Cow (Bovine) Paired Box 7 (PAX7) interaction partners

  1. four novel polymorphisms were identified in the Pax7 gene; the association analysis of genotypes in the single and combined SNP(s) revealed consistent effects on growth traits in NY cattle

Mouse (Murine) Paired Box 7 (PAX7) interaction partners

  1. results support the concept that lack of functional Pax7 promotes proliferation of differentiating ESCs (show NR2E3 Proteins) and for this reason more of them can turn into myogenic lineage.

  2. the absence of functional Pax7 does not prevent the in vitro myogenic differentiation of embryonic stem cells.

  3. These results underscore DNA demethylation as a key mechanism driving myogenesis and identify specific Pax7-mediated DNA demethylation signatures to acquire and maintain the muscle-cell identity.

  4. we propose that Nedd4 functions as a novel Pax7 regulator, which activity is temporally and spatially controlled to modulate the Pax7 protein levels and therefore satellite cell fate.

  5. miR (show MLXIP Proteins)-431 transgenic mice are a unique genetic model for investigating the cellular features and biological functions of Pax7(Lo) satellite cells during muscle development and regeneration.

  6. Caspase 3 (show CASP3 Proteins) cleavage of Pax7 has a role in inhibiting self-renewal of satellite cells

  7. Brg1 (show SMARCA4 Proteins) functions as a positive regulator for cellular proliferation and survival of primary myoblasts via pax7.

  8. Loss of Pax7 expression is associated with craniofacial abnormalities.

  9. Low RAGE (show AGER Proteins) activity in embryonal rhabdomyosarcoma cells results in high PAX7 levels that sustain migration and invasiveness.

  10. PAX7+ subset of A(single) spermatogonia functions as robust testis stem cells that maintain fertility in normal spermatogenesis in healthy mice and mediate recovery after severe germline injury, such as occurs after cancer therapy.

Zebrafish Paired Box 7 (PAX7) interaction partners

  1. Pax7 identifies neural crest, chromatophore lineages and pigment stem cells during development.

PAX7 Protein Profile

Protein Summary

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Paired Box 7 Proteins (PAX7)

  • paired box 7 (PAX7)
  • paired box 7 (LOC100346989)
  • paired box 7 (pax7)
  • paired box 7 (Pax7)
  • paired box gene 7 (Pax7)
  • paired box gene 7a (pax7a)
  • HUP1 protein
  • Pax-7 protein
  • pax7 protein
  • PAX7B protein
  • pax7c protein
  • pax7d protein
  • pax7e protein
  • RGD1564360 protein
  • RMS2 protein

Protein level used designations for Paired Box 7 Proteins (PAX7)

paired box 7 , paired box gene 7 , transcription factor pax-7 , PAX7 transcriptional factor , paired box homeotic gene 7 , paired box protein Pax-7 , paired domain gene 7 , myogenic specification paired-box transcription factor Pax7 , paired box transcription factor PAX7 , paired box homeotic gene 7a , paired box homeotic gene 7c , paired box homeotic gene 7d , paired box homeotic gene 7e

456574 Pan troglodytes
494466 Sus scrofa
100322892 Meleagris gallopavo
100346989 Oryctolagus cuniculus
5081 Homo sapiens
496378 Xenopus laevis
395942 Gallus gallus
487408 Canis lupus familiaris
536229 Bos taurus
500574 Rattus norvegicus
18509 Mus musculus
30587 Danio rerio
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