Paired Related Homeobox 1 Proteins (PRRX1)

The DNA-associated protein encoded by PRRX1 is a member of the paired family of homeobox proteins localized to the nucleus. Additionally we are shipping PRRX1 Antibodies (88) and PRRX1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRRX1 5396 P54821
PRRX1 18933 P63013
PRRX1 266813 P63014
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Top PRRX1 Proteins at

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days

PRRX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Paired Related Homeobox 1 (PRRX1) Interaction Partners

Human Paired Related Homeobox 1 (PRRX1) interaction partners

  1. LGR5 (show LGR5 Proteins)-expressing fraction of CD54 (show ICAM1 Proteins)+ cells represents gastric cancer CSCs, in which LGR5 (show LGR5 Proteins) is closely associated with stemness and EMT (show ITK Proteins) core genes

  2. miR (show MLXIP Proteins)-655 inhibits the acquisition of the epithelial-mesenchymal transition phenotype in triple-negative breast cancer by down-regulating Prrx1, thereby inhibiting cell migration and invasion during cancer progression.

  3. Decreased Expression of PRRX1 was Associated with Hepatocellular Carcinoma.

  4. the switch from Prrx1b to Prrx1a governs EMT (show ITK Proteins) plasticity in both mouse models of PDAC and human PDAC

  5. These findings demonstrate that PRRX1 promotes epithelial-mesenchymal transition in gastric cancer cells

  6. Our results indicate that activation of Notch (show NOTCH1 Proteins) signaling by PRRX1 is associated with the promotion of glioblastoma cell invasion.

  7. We conclude that miR (show MLXIP Proteins)-146b-5p has a role in cell proliferation and invasion, and that PRRX1 plays an important role in papillary thyroid carcinoma epithelial-mesenchymal transition and disease progression.

  8. Overexpression of PRRX1 in stably overexpressed-miR (show MLXIP Proteins)-124 cell lines could rescue the effects of radiosensitivity enhancement brought by miR (show MLXIP Proteins)-124.

  9. In the rare variant joint analysis, damaging variants within the PRRX1 region showed significant association with AF.

  10. PRRX1 is an indicator of metastasis and poor prognosis in colorectal cancer cases.

Mouse (Murine) Paired Related Homeobox 1 (PRRX1) interaction partners

  1. Postnatal PRX1 (show PRDX1 Proteins)-expressing stem cells of the calvaria are required for bone regeneration.

  2. Data show that p38alpha (show MAPK14 Proteins) mitogen-activated protein kinase (show MAPK1 Proteins) (MAPK (show MAPK1 Proteins)) in paired related homeobox 1 protein (Prx1 (show PRDX1 Proteins)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG (show TNFRSF11B Proteins)) production.

  3. These data suggest the presence of a novel oxidative-stress-handling pathway where the anti-p53 (show TP53 Proteins) molecule fortilin (show TPT1 Proteins) augments the peroxidase PRX1 (show PRDX1 Proteins) by protecting it against degradation and inactivation of the enzyme.

  4. Induction of Prx1 (show PRDX1 Proteins) by hypoxia regulates heme oxygenase-1 (show HMOX1 Proteins) via NF-kappaB (show NFKB1 Proteins) in oral cancer.

  5. PRX-1 has a regulatory role in NF-kappaB (show NFKB1 Proteins) nuclear translocation.

  6. The data of this study suggested that Prx1 (show PRDX1 Proteins) plays an important role as a key switch for neural cell lineage determination and the maintenance of the self-renewal of adult NSCs at several stages in the adult brain.

  7. These observations suggest that increased Prrx1 expression may promote TGFbeta (show TGFB1 Proteins) activity in adipose tissue and thereby contribute to aberrant adipocyte function during obesity.

  8. The two isoforms, Prrx1a and Prrx1b, regulate migration and invasion, respectively, in pancreatic cancer cells

  9. The results suggested that scarless skin-wound healing may require activation of the prx1 (show PRDX1 Proteins) limb enhancer, and competence to activate the enhancer is probably a prerequisite for epimorphic regeneration, such as limb regeneration.

  10. These results identify the homeobox protein (show HOXA1 Proteins) Prx1 (show PRDX1 Proteins) as an obligate mediator of TNF (show TNF Proteins) inhibition of Osx (show SP7 Proteins) and differentiation of osteoblast progenitors.

PRRX1 Protein Profile

Protein Summary

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns.

Gene names and symbols associated with PRRX1

  • paired related homeobox 1a (prrx1a)
  • paired related homeobox 1 (PRRX1)
  • similar to PEPP subfamily gene 2 (PRRX1)
  • paired related homeobox 1 (Prrx1)
  • A230024N07Rik protein
  • AA755424 protein
  • AGOTC protein
  • AI385634 protein
  • AI843499 protein
  • cb329 protein
  • gMHox protein
  • homeobox protein
  • K-2 protein
  • mHox protein
  • PHOX1 protein
  • Pmx protein
  • Pmx1 protein
  • PRRX1 protein
  • Prx-1 protein
  • Prx1 protein
  • wu:fa09h05 protein
  • wu:fb52c01 protein
  • zgc:64055 protein

Protein level used designations for PRRX1

paired mesoderm homeo box 1 , paired related homeobox 1 , prx1 , paired mesoderm homeobox 1 , paired mesoderm homeobox protein 1 , similar to PEPP subfamily gene 2 , homeobox protein PHOX1 , paired mesoderm homeobox 1 isoform pmx-1b , paired-related homeobox protein 1 , homeobox protein K-2 , homeobox protein mHox , rHox , homeobox protein MHOX , paired-related homeotic gene product

406431 Danio rerio
540901 Bos taurus
609105 Canis lupus familiaris
702704 Macaca mulatta
736677 Pan troglodytes
695352 Macaca mulatta
5396 Homo sapiens
18933 Mus musculus
266813 Rattus norvegicus
373941 Gallus gallus
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