Pannexin 1 Proteins (PANX1)

The protein encoded by PANX1 belongs to the innexin family. Additionally we are shipping Pannexin 1 Antibodies (49) and Pannexin 1 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PANX1 24145 Q96RD7
PANX1 55991 Q9JIP4
PANX1 315435 P60570
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Top Pannexin 1 Proteins at

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 15 to 18 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 15 to 18 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
HOST_Escherichia coli (E. coli) Rat Un-conjugated   100 μg Log in to see 11 to 18 Days

PANX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine) ,
Rat (Rattus)

More Proteins for Pannexin 1 (PANX1) Interaction Partners

Zebrafish Pannexin 1 (PANX1) interaction partners

  1. Extracellular ATP hydrolysis via NTPDase1 (show ENTPD1 Proteins) action inhibits synaptic transmission by pannexin 1-mediated increase in pH buffering of the synaptic cleft.

  2. The existence of two Panx1 proteins in zebrafish displaying distinct tissue distribution, protein modification and electrophysiological properties, suggests that both proteins fulfill different functions in vivo.

  3. The function of panx1 channel is significantly reduced following mutation of a single cysteine residue (C282W) in the fourth transmembrane region of panx1.

Human Pannexin 1 (PANX1) interaction partners

  1. presence of the Panx1-400C allele was not associated with platelet reactivity in stable cardiovascular patients.

  2. Overactive Panx-1 promotes cancer cell survival in the context of mechanical deformation. Panx-1 inhibitors can be used to treat highly metastatic cancer. Mechanosensitive Panx-1 channels will be a new target for the prevention of metastasis and stress-induced diseases.

  3. The results of this study do not support a major contribution of PANX1-3 to disease risk of schizophrenia according to DSM-5.

  4. a pivotal role of P2X7 receptor (show P2RX7 Proteins)-pannexin-1 in oxysterols toxicity in retinal cells

  5. Data indicate that the consanguineous parents are each heterozygous for Pannexin1 (PANX1) but are not affected by the multiorgan syndromes.

  6. CBX (show CBX1 Proteins) and other inhibitors, including probenecid, attenuate Panx1 channel activity through modulation of the first extracellular loop.

  7. Decreased Panx1 function is a response to cell acidification mediated by IFN-gamma-induced (show SAMHD1 Proteins) up-regulation of Duox2 (show DUOX2 Proteins).

  8. PANX-1 plays an important role in the release of cytokines and glutamate (show GRIN1 Proteins) in a tumor cell line.

  9. The frequency of Panx1-400C homozygotes was higher among cardiovascular patients with hyper-reactive platelets. The Panx1-400C variant encodes a gain-of-function channel that enhances collagen-induced ATP release and platelet aggregation.

  10. Pannexin1-dependent pathophysiological eATP release in lipoapoptosis is capable of stimulating migration of human monocytes

Mouse (Murine) Pannexin 1 (PANX1) interaction partners

  1. Diabetic C57BL/6J-Ins2Akita mice were used to evaluate in vivo effects of high glucose on P2R and Panx1

  2. Pharmacological blockade or genetic deletion of Panx1 channels inhibits CD4 (show CD4 Proteins)+ T lymphocyte polarization and migration induced by the chemokine (show CCL1 Proteins) SDF-1alpha/CXCL12 (show CXCL12 Proteins). Panx1 deficiency delayed experimental autoimmune encephalomyelitis symptoms because of the decreased infiltration of CD4 (show CD4 Proteins)+ T lymphocytes into the CNS.

  3. data suggest that Panx1 and Panx3 (show PANX3 Proteins) are not essential for baseline hearing in mice tested, but the therapeutic targeting of Panx3 (show PANX3 Proteins) may prove protective against mid-high-frequency hearing loss caused by loud NE.

  4. Pannexin1 (Panx1) is dynamically regulated throughout mammary gland development.

  5. These results indicate that activation of Panx1 and P2X7 (show P2RX7 Proteins) R are required for apoptotic osteocytes in fatigued bone to trigger RANKL (show TNFSF11 Proteins) production in neighboring bystander osteocytes and implicate ATP as an essential signal mediating this process.

  6. Panx1 is expressed in the central and peripheral nervous system during early developmental stages.

  7. this study provides the first demonstration of Panx1 channel morphology and assembly in intact cells.

  8. Panx1 in the heart influences different electrophysiological parameters involving depolarization, repolarization and atrial vulnerability causing atrial fibrillation.

  9. ATP released by myocardial cells through Pannexin-1 channel during ischemia could evoke calcium responses in cardiac sympathetic nerve fibers.

  10. Platelets of Panx1-/- mice showed reduced collagen-induced aggregation as compared to those of WT mice.

Pannexin 1 (PANX1) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.

Gene names and symbols associated with Pannexin 1 Proteins (PANX1)

  • pannexin 1a (panx1a)
  • pannexin 1 (PANX1)
  • pannexin 1 (panx1)
  • pannexin 1 (Panx1)
  • Pannexin 1 (Panx1)
  • AI847747 protein
  • MRS1 protein
  • Pannexin-1 protein
  • pannexin1 protein
  • PANX1 protein
  • PX1 protein
  • UNQ2529 protein
  • zgc:55631 protein

Protein level used designations for Pannexin 1 Proteins (PANX1)

pannexin 1 , pannexin-1 , innexin

393890 Danio rerio
466751 Pan troglodytes
697204 Macaca mulatta
772164 Gallus gallus
100014304 Monodelphis domestica
100170473 Xenopus (Silurana) tropicalis
100171730 Pongo abelii
24145 Homo sapiens
607532 Canis lupus familiaris
528169 Bos taurus
55991 Mus musculus
315435 Rattus norvegicus
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