Patatin-Like phospholipase Domain Containing 4 Proteins (PNPLA4)

PNPLA4 encodes a member of the patatin-like family of phospholipases. Additionally we are shipping PNPLA4 Antibodies (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PNPLA4 8228 P41247
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Top PNPLA4 Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see 10 to 12 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days

PNPLA4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Patatin-Like phospholipase Domain Containing 4 (PNPLA4) Interaction Partners

Human Patatin-Like phospholipase Domain Containing 4 (PNPLA4) interaction partners

  1. These results strongly suggest that PNPLA9 (show PLA2G6 Proteins), -6 and -4 play a key role in GPL (show IL31RA Proteins) turnover and homeostasis in human cells. A hypothetical model suggesting how these enzymes could recognize the relative concentration of the different GPLs is proposed

  2. iPLA2epsilon (adiponutrin (show PNPLA3 Proteins)), iPLA2zeta (TTS-2.2), and iPLA2eta (GS2) are three novel TAG lipases/acylglycerol transacylases that likely participate in TAG hydrolysis and the acyl-CoA (show GNPAT Proteins) independent transacylation of acylglycerols

  3. The GS2 (show RAB27A Proteins) gene (PNPLA4) encodes a keratinocyte retinyl ester hydrolase (show CES1 Proteins). The protein also catalyzes fatty acyl CoA (show GNPAT Proteins)-dependent and -independent retinol esterification, using triolein as substrate and generates diacylglyceride and free fatty acid.

  4. we report the identity of an inhibitor, TIP47 (show PLIN3 Proteins), which prevents retinylester hydrolysis catalyzed by GS2 (show RAB27A Proteins) lipase (show LIPG Proteins) and hormone-sensitive lipase (show LIPE Proteins)

  5. GS2 promotes RE accumulation and may do so either as a catalyst or as a regulatory protein that enhances retinylesters formation catalyzed by other acyl transferases.

  6. No association between genetic variants in PNPLA4 genes and childhood and adolescent obesity

PNPLA4 Protein Profile

Protein Summary

This gene encodes a member of the patatin-like family of phospholipases. The encoded enzyme has both triacylglycerol lipase and transacylase activities and may be involved in adipocyte triglyceride homeostasis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome Y.

Gene names and symbols associated with PNPLA4

  • patatin like phospholipase domain containing 4 L homeolog (pnpla4.L)
  • patatin like phospholipase domain containing 4 (PNPLA4)
  • DXS1283E protein
  • GS2 protein
  • iPLA2eta protein
  • PNPLA4 protein

Protein level used designations for PNPLA4

patatin-like phospholipase domain-containing protein 4 , patatin-like phospholipase 4 , GS2 , patatin-like phospholipase domain containing 4 , IPLA2 eta , calcium independent phospholipases A2 eta

496144 Xenopus laevis
418653 Gallus gallus
491729 Canis lupus familiaris
100294680 Sus scrofa
785567 Bos taurus
8228 Homo sapiens
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