Patatin-Like phospholipase Domain Containing 3 (PNPLA3) ELISA Kits

The protein encoded by PNPLA3 is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. Additionally we are shipping PNPLA3 Antibodies (93) and PNPLA3 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PNPLA3 80339 Q9NST1
PNPLA3 116939 Q91WW7
PNPLA3 362972  
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Top PNPLA3 ELISA Kits at antibodies-online.com

Showing 3 out of 14 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 21 pg/mL 0.1-1.000 ng/mL   96 Tests Log in to see 2 to 3 Days
$452.10
Details
Rat 0.057 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 15 to 17 Days
$973.11
Details
Human 0.062 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 13 to 16 Days
$589.47
Details

Top referenced PNPLA3 ELISA Kits

  1. Human PNPLA3 ELISA Kit for Competition ELISA - ABIN1979134 : Lake, Sun, Li, Kim, Johnson, Li, Revett, Shih, Liu, Paulsen, Gimeno: Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members. in Journal of lipid research 2005 (PubMed)
    Show all 3 Pubmed References

  2. Human PNPLA3 ELISA Kit for Competition ELISA - ABIN1979137 : Moldes, Beauregard, Faraj, Peretti, Ducluzeau, Laville, Rabasa-Lhoret, Vidal, Clément: Adiponutrin gene is regulated by insulin and glucose in human adipose tissue. in European journal of endocrinology / European Federation of Endocrine Societies 2006 (PubMed)
    Show all 3 Pubmed References

  3. Human PNPLA3 ELISA Kit for Competition ELISA - ABIN1979131 : Lake, Sun, Li, Kim, Johnson, Li, Revett, Shih, Liu, Paulsen, Gimeno: Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members. in Journal of lipid research 2005 (PubMed)
    Show all 11 Pubmed References

More ELISA Kits for PNPLA3 Interaction Partners

Human Patatin-Like phospholipase Domain Containing 3 (PNPLA3) interaction partners

  1. The PNPLA3 rs738409 GG genotype is positively associated with hepatic steatosis in Asian patients with chronic hepatitis C.

  2. The study proposes that polymorphisms in the PNPLA3 gene have highly predictive value in the development of nonalcoholic fatty liver disease and are independently associated with the severity of liver histology in patients with NAFLD (show TSC2 ELISA Kits).

  3. PNPLA3 association with adiposity and the risk of the nonalcoholic fatty liver disease

  4. PNPLA3 gene variant is associated with the risk of developing liver fibrosis and cirrhosis in an Eastern European population.

  5. PNPLA3 acts as a positive modulator of activated human hepatic stellate cells, affecting cytokines secretion.

  6. The results show that in obese patients, the presence of the PNPLA3 p.I148M allele might be associated with greater improvement of hepatic steatosis after bariatric surgery in comparison to carriers of PNPLA3 wild-type alleles. The also lost more weight and had reduced liver fat content.

  7. Fibrosis stages were affected by the PNPLA3 (P = 0.042) and MBOAT7 (show MBOAT7 ELISA Kits) (P = 0.021) but not by the TM6SF2 polymorphism (P > 0.05). The PNPLA3, TM6SF2, and MBOAT7 (show MBOAT7 ELISA Kits) variants are associated with increased liver injury. The TM6SF2 variant seems to modulate predominantly hepatic fat accumulation, whereas the MBOAT7 (show MBOAT7 ELISA Kits) polymorphism is linked to fibrosis. The PNPLA3 polymorphism confers risk of both increased steatosis and fibrosis

  8. PNPLA3 rs738409 (C>G) was associated with the risk of both advanced liver fibrosis and steatosis in patients with chronic hepatitis C, especially among Caucasian populations

  9. we provide evidence to indicate that PNPLA3-mediated retinol release may protect against liver fibrosis by inducing a specific signature of proteins involved in extracellular matrix remodelling

  10. The percentage of the PNPLA3 rs738409 GG genotype in NAFLD (show TSC2 ELISA Kits) patients was also significantly higher than that in the controls.

Mouse (Murine) Patatin-Like phospholipase Domain Containing 3 (PNPLA3) interaction partners

  1. Neither ablation nor overexpression of wild-type PNPLA3 affects liver fat content in mice, whereas hepatic overexpression of the human 148M transgene causes steatosis.

  2. PNPLA3 plays a role in remodeling TAG in lipid droplets, as they accumulate in response to food intake

  3. adiponutrin/PNPLA3 is regulated by two key factors of the glycolytic and lipogenic pathways, raising the question of its implication in the metabolism of carbohydrates and lipids

  4. data argue against a role for Pnpla3 loss-of-function in fatty liver disease or metabolic syndrome in mice.

  5. Loss of Pnpla3 does not cause fatty liver, liver enzyme elevation, or insulin (show INS ELISA Kits) resistance in mice.

  6. Microarray-based gene profiling showed that the expression level of PNPLA3 in hepatocytes is correlated with that of genes associated with the lipogenic pathway such as ME1 (show ME1 ELISA Kits), SPOT14 (show THRSP ELISA Kits), and SCD1 (show SCD ELISA Kits).

  7. data suggest that murine ATGL (show PNPLA2 ELISA Kits) but not adiponutrin contributes to net adipocyte lipolysis and that ATGL (show PNPLA2 ELISA Kits) and adiponutrin are oppositely regulated by insulin (show INS ELISA Kits) both in vitro and in vivo

PNPLA3 Antigen Profile

Antigen Summary

The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes.

Gene names and symbols associated with PNPLA3

  • patatin-like phospholipase domain containing 3 (PNPLA3) antibody
  • patatin-like phospholipase domain containing 3 (Pnpla3) antibody
  • Adpn antibody
  • C22orf20 antibody
  • iPLA(2)epsilon antibody

Protein level used designations for PNPLA3

acylglycerol O-acyltransferase , adiponutrin , calcium-independent phospholipase A2-epsilon , iPLA2-epsilon , iPLA2epsilon , patatin-like phospholipase domain-containing protein 3

GENE ID SPECIES
80339 Homo sapiens
116939 Mus musculus
362972 Rattus norvegicus
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