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anti-Pepsinogen C (PGC) Antibodies

PGC encodes an aspartic proteinase that belongs to the peptidase family A1. Additionally we are shipping PGC Kits (48) and PGC Proteins (23) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PGC 5225 P20142
PGC 109820 Q9D7R7
PGC 24864 P04073
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Top anti-PGC Antibodies at

Showing 10 out of 161 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
Human Mouse Un-conjugated ELISA (Capture), EIA   0.2 mg Log in to see 6 to 8 Days
Human Mouse Un-conjugated IHC (p), ELISA Immunochemical staining of human PGC in human stomach (from 3 donors) with mouse monoclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Log in to see 16 Days
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemistry (IHC) analyzes of Pepsin C antibody in paraffin-embedded human lung carcinoma tissue. Western blot (WB) analyzes of Pepsin C antibody in extracts from Jurkat cells. 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of Pepsinogen C staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Pepsinogen C expression in DU145 (A), A673 (B) whole cell lysates. 200 μL Log in to see 9 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat stomach labeled with Anti-PG-C/Pepsinogen 2 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
Human Rabbit Un-conjugated ELISA, IHC, WB   100 μL Log in to see 14 Days
Human Mouse Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
Rat Mouse Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days

PGC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) ,

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Rat (Rattus) , ,
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Top referenced anti-PGC Antibodies

  1. Human Monoclonal PGC Primary Antibody for EIA, IHC (p) - ABIN1108614 : Varis, Samloff, Ihämaki, Siurala: An appraisal of tests for severe atrophic gastritis in relatives of patients with pernicious anemia. in Digestive diseases and sciences 1979 (PubMed)
    Show all 5 references for ABIN1108614

More Antibodies against PGC Interaction Partners

Human Pepsinogen C (PGC) interaction partners

  1. Pepsinogen-II 100 bp ins (show INS Antibodies)/del gene polymorphism and its elevated circulating levels are associated with gastric cancer, particularly with Helicobacter pylori infection and intestinal metaplasia.

  2. Results suggest that rs9471643 CG and rs6458238 AG/AA genotypes have important roles in up-regulating PGC expression, which may partially explain why individuals with these favorable genotypes have decreased risks of getting gastric cancer.

  3. Data show that SNP interactions among H. pylori-related genes PGC, PTPN11 (show PTPN11 Antibodies), and IL1B (show IL1B Antibodies), are associated with susceptibility to gastric carcinogenesis.

  4. Serum pepsinogens I (PGI (show BGN Antibodies)) and II (PGII (show DCN Antibodies)), gastrin (show GAST Antibodies) 17 (G-17), and antibodies against whole H. pylori, or cytotoxin-associated gene A (CagA (show S100A8 Antibodies)) antigen among 309 consecutive patients, were measured.

  5. The results highlight an important role of PGC rs3789210 and rs6939861 in altering susceptibility to atrophic gastritis and/or gastric cancer.

  6. Pepsinogen II is a good marker of corpus morphological changes before and after H. pylori eradication.

  7. High serum Pepsinogen II level is associ9ated with the progression of gastric precancerous lesions.

  8. An interaction effect of pri-let-7a-1 rs10739971 polymorphism with ERCC6 (show ERCC6 Antibodies) rs1917799 polymorphism was observed for the risk of gastric cancer.

  9. Pepsin and pepsinogen in middle ear effusion are probably caused by LPR (show FAS Antibodies) and may be involved in the pathogenesis of OME.

  10. High serum pepsinogen II is associated with gastric cancer development and activity of Helicobacter pylori-associated chronic gastritis.

PGC Antigen Profile

Protein Summary

This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.

Gene names and symbols associated with anti-Pepsinogen C (PGC) Antibodies

  • progastricsin (pepsinogen C) (PGC) antibody
  • progastricsin (pepsinogen C) (Pgc) antibody
  • 2210410L06Rik antibody
  • CPGC antibody
  • Gastricsin antibody
  • PEPC antibody
  • Pg-1 antibody
  • PG1 antibody
  • PGC antibody
  • PGII antibody
  • PGNC antibody
  • Upg-1 antibody
  • Upg1 antibody

Protein level used designations for anti-Pepsinogen C (PGC) Antibodies

gastricsin , pepsinogen C , pepsin C , pepsinogen group II , preprogastricsin , urinary pepsinogen 1 , Urinary pepsinogen 1 , gastricsin-like

554184 Monodelphis domestica
5225 Homo sapiens
109820 Mus musculus
395690 Gallus gallus
24864 Rattus norvegicus
100009323 Oryctolagus cuniculus
100135598 Cavia porcellus
100404738 Callithrix jacchus
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