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Binds to heparin. Additionally we are shipping POSTN Antibodies (182) and POSTN Kits (68) and many more products for this protein.
Showing 10 out of 28 products:
High POSTN expression is associated with glioblastoma cell invasion.
By serial deletion mapping of the first FAS (show FAS Proteins) I domain, we identified a peptide sequence (amino acids 142-151) of periostin for stimulation of chemotactic migration, adhesion, proliferation and endothelial tube formation of human ECFCs in vitro. Chemotactic migration of ECFCs induced by the periostin peptide was blocked by pre-incubation with an anti-beta5 integrin neutralizing antibody
high epithelial periostin expression was associated with reduced disease-free survival and overall survival in univariate and multivariate analysis. Periostin may play an important role in the progression of breast tumor, and epithelial periostin expression may serve as a new parameter for prediction of prognosis in patients with invasive breast carcinoma .
knockdown of POSTN inhibited expression of phosphorylated c-Jun N-terminal kinase
These results support an important role of periostin in the biology of myeloma and reveal periostin as a possible target for the development of antimyeloma drugs.
The results indicated that periostin is a pivotal molecule for retinal fibrovascular membrane formation and a promising therapeutic target for the proliferative vitreoretinal diseases. (Review)
The role of periostin in the pathogenesis of skin diseases has been summarized. (Review)
Periostin is highly expressed in the lungs of asthmatic patients, contributes to mucus secretion, airway fibrosis and remodeling and is recognized as a biomarker of Th2 high inflammation. (Review)
Periostin-gene and protein structure has been described. (Review)
The multifaceted role of periostin in priming the tumor microenvironments for tumor progression has been summarized. (Review)
this study shows that periostin regulates fibrocyte function to promote myofibroblast differentiation and lung fibrosis
Genetic or pharmaco-genetic inhibition of periostin in animal models of renal disease was efficient in arresting the progression of the kidney pathology. (Review)
TGFBI (show TGFB1 Proteins) and periostin act similarly in the heart in affecting fibrosis and disease responsiveness.
Results suggest that stromal cell periostin (POSTN) supports both normal hematopoietic progenitor cells (HPCs) and leukemia-initiating cells in vitro.
the expressions of the periostin splice variants were increased in ischemic retinas.
POSTN regulates the scar formation after spinal cord injuries.
periostin in the extracellular matrix architecture prevents pulmonary leakage of blood fluid, thus increasing the survival rate in mice with acute lung injury
POSTN promotes the pulmonary accumulation of myeloid-derived suppressor cells (MDSCs) during the early stage of breast tumour metastasis. Postn deletion decreases neutrophil and monocytic cell populations in the bone marrow of mice and suppresses the accumulation of MDSCs to premetastatic sites.
Fibrillin-2 (show FBN2 Proteins) and periostin are target genes in Osterix (show SP7 Proteins)-mediated osteoblast differentiation.
Periostin mediates intestinal inflammation through the activation of NF-kappaB (show NFKB1 Proteins) signaling, which suggests that periostin is a potential therapeutic target for inflammatory bowel disease.
These results suggest that periostin is one of the local contributing factors in bone and periodontal tissue remodeling following mechanical stress during experimental tooth movement [periostin].
Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.
, periostin, osteoblast specific factor
, extracellular adhestion molecule
, osteoblast-specific factor 2
, osteoblast specific factor 2 (fasciclin I-like)
, periodontal ligament-specific periostin
, periostin isoform thy2
, periostin isoform thy4
, periostin isoform thy6
, periostin isoform thy8
, periostin-like factor
, periostin variant 6
, periostin variant 7
, periostin variant 8
, periostin variant 9