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Phospholipase A2, Group III Proteins (PLA2G3)

PLA2G3 belongs to the family of secreted phospholipase A2 (sPLA2\; EC proteins. Additionally we are shipping PLA2G3 Antibodies (43) and PLA2G3 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PLA2G3 50487 Q9NZ20
Rat PLA2G3 PLA2G3 289733  
Mouse PLA2G3 PLA2G3 237625  
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Top PLA2G3 Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days

PLA2G3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Phospholipase A2, Group III (PLA2G3) Interaction Partners

Human Phospholipase A2, Group III (PLA2G3) interaction partners

  1. Studies indicate that the expression of secreted phospholipases A2 (sPLA2s), most notably the group IIA, III and X enzymes, is dysregulated in various malignant tissues.

  2. Studies indicate that phospholipase A2 receptor 1 (PLA2R1 (show PLA2R1 Proteins)) may act as a clearance or signaling receptor for secreted phospholipase A2 (show YWHAZ Proteins) (sPLA2s (show PLA2G2D Proteins)).

  3. Data indicate that the expression of genes encoding hGIIA, hGIII and hGX sPLA2s (show PLA2G2D Proteins) (PLA2G2A (show PLA2G2A Proteins), PLA2G3 and PLA2G10 (show PLA2G10 Proteins), respectively) in breast tumour biopsies differs from that in normal tissues.

  4. we describe that PLA2G3 gene silencing produced a marked inhibition of xanthine/xanthine oxidase (show XDH Proteins) induced cell death, and that PLA2G3 polymorphisms are associated with Alzheimer disease in a Spanish case-control sample.

  5. The availability of the human group III phospholipase A (show HRASLS Proteins)(2) (hIIIPLA(2)) amino acid sequence offers an opportunity to study its structural features by modeling.

  6. Secreted PLA2 (show YWHAZ Proteins) III induces apoptosis of primary cortical neurons in culture by suppressing production of Bcl-xl (show BCL2L1 Proteins), promoting Bax (show BAX Proteins), augmenting caspase 3 (show CASP3 Proteins) and cleaving alpha-fodrin (show SPTAN1 Proteins).

  7. Lys (show LYZ Proteins) 43 and Asp (show ASIP Proteins) 46 in rhUG are critical residues for the sPLA2 (show PLA2G2A Proteins)-inhibitory activity of UG

  8. cellular arachidonate (AA) release and prostaglandin (PG) production are regulated by novel classes of secretory phospholipase A (show HRASLS Proteins)(2)s (sPLA(2 (show PLA2G2A Proteins))s), groups III and XII

  9. sPLA(2 (show PLA2G2A Proteins))-III may have a role in cancer development by stimulating tumor cell growth and angiogenesis

  10. potential contribution of sPLA2-III to neuronal differentiation and its function under certain conditions

Mouse (Murine) Phospholipase A2, Group III (PLA2G3) interaction partners

  1. Findings show a key role of Pla2g3 on the reduction of IDE (show IDE Proteins), and suggest that cerebrum specific increase of Pla2g3 is involved in the initiation and/or progression of Alzheimer disease.

  2. Data indicate a PLA2G3-lipocalin (show APOD Proteins)-type PGD2 synthase (L-PGDS)-PGD2 (show PTGDS Proteins) receptor DP1 (show PTGDR Proteins) loop that drives mast cell maturation.

  3. the atypical sPLA2 (show PLA2G2A Proteins) family member sPLA2-III has a role in epididymal lipid homeostasis and its perturbation may lead to sperm dysfunction

  4. sPLA(2 (show PLA2G2A Proteins))-III may have a role in cancer development by stimulating tumor cell growth and angiogenesis

  5. This study showed that endogenous group III sPLA2 (show PLA2G2A Proteins) (PLA2G3) is expressed in mouse skin and that transgenic mice overexpressing human PLA2G3 spontaneously develop skin inflammation.

PLA2G3 Protein Profile

Protein Summary

PLA2G3 belongs to the family of secreted phospholipase A2 (sPLA2\; EC proteins. These Ca(2+)-dependent lipolytic enzymes have a conserved Ca(2+)-binding loop and a his-asp dyad in the catalytic site (Murakami et al., 2003

Gene names and symbols associated with PLA2G3

  • phospholipase A2, group III (PLA2G3)
  • phospholipase A2, group III (Pla2g3)
  • 9130003P18Rik protein
  • GIII-SPLA2 protein
  • PLA2G3 protein
  • SPLA2III protein

Protein level used designations for PLA2G3

phospholipase A2, group III , group 3 secretory phospholipase A2-like , GIII sPLA2 , group 3 secretory phospholipase A2 , group III secreted phospholipase A2 , group III secretory phospholipase A2 , phosphatidylcholine 2-acylhydrolase 3 , phosphatidylcholine 2-acylhydrolase GIII , sPLA2-III

470183 Pan troglodytes
486361 Canis lupus familiaris
718321 Macaca mulatta
100459011 Pongo abelii
100585880 Nomascus leucogenys
50487 Homo sapiens
289733 Rattus norvegicus
527631 Bos taurus
237625 Mus musculus
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