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May play a role in placental development (By similarity).. Additionally we are shipping Placenta-Specific 1 Antibodies (22) and Placenta-Specific 1 Kits (6) and many more products for this protein.
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Plac1 plays a pivotal role in the progression of HCC (show FAM126A Proteins), and may serve as a novel therapeutic target for Hepatocellular carcinoma.
PLAC1 was mainly expressed in the human villous syncytiotrophoblast (STB) layer throughout gestation, and the expression level of PLAC1 was significantly elevated during human trophoblast syncytialization.
PLAC1/CP1 provides a marker for identifying gastric cancers with poor prognosis, and suggest that PLAC1/CP1 may provide a useful target for immunotherapy.
Data suggests that PLAC1 plays an important role in human placental trophoblast invasion and migration.
This data suggests that the Epstein-Barr virus-induced PLAC1 is a member of the cancer/testis group of tumor antigens.
PLAC1/CP1 antigen is a possible prognostic marker of colorectal carcinoma, and PLAC1/CP1 p41 (show EPB41 Proteins)-50 and PLAC1/CP1 p69 (show ICA1 Proteins)-77 are novel HLA-A*0201-restricted CD8 (show CD8A Proteins)+ T cell epitopes
NCOA3 (show NCOA3 Proteins) is a selective co-activator of estrogen receptor alpha (show ESR1 Proteins)-mediated transactivation of PLAC1.
we identified a novel specific antitrophoblast antibody, anti-PLAC1, in infertile women with repeated unexplained implantation failure. PLAC1 shows placenta-specific expression and is localized primarily in the syncytiotrophoblast.
A novel HLA-A2-restricted cytotoxic T lymphocyte epitope from cancer-testis antigen PLAC1 has been identified in breast cancer.
RXRalpha (show RXRA Proteins) and LXR (show NR1H3 Proteins) activate two promoters in placenta- and tumor-specific expression of PLAC1.
Our findings suggest that Plac1 is involved in trophoblast cell proliferation, differentiation, and migration
Plac1 (placenta-specific 1) is widely expressed during fetal development and is associated with a lethal form of hydrocephalus.
Plac1 is a paternally imprinted, X-linked gene essential for normal placental and embryonic development.
May play a role in placental development (By similarity).
, placenta-specific protein 1
, cancer/testis antigen 92
, ectoplacental cone, invasive trophoblast giant cells, extraembryonic ectoderm and chorion sequence 26