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Podoplanin Proteins (PDPN)

PDPN encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. Additionally we are shipping Podoplanin Antibodies (421) and Podoplanin Kits (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PDPN 10630 Q86YL7
PDPN 14726 Q62011
PDPN 54320 Q64294
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Top Podoplanin Proteins at

Showing 10 out of 32 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Mouse Fc Tag 100 μg Log in to see 10 to 12 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
HOST_Human Cells Human His tag,Fc Tag 100 μg Log in to see 16 Days
HOST_Human Cells Mouse His tag,Fc Tag 100 μg Log in to see 16 Days
HOST_Mammalian Cells Human His tag   50 μg Log in to see 5 Days
HOST_Baculovirus infected Insect Cells Mouse His tag 100 μg Log in to see 16 Days

PDPN Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, , , , ,
Mouse (Murine) , , , ,
, , , ,
Rat (Rattus) , ,

Top referenced Podoplanin Proteins

  1. Mouse (Murine) Podoplanin Protein expressed in HEK-293 - ABIN2666857 : Kato, Fujita, Kunita, Sato, Kaneko, Osawa, Tsuruo: Molecular identification of Aggrus/T1alpha as a platelet aggregation-inducing factor expressed in colorectal tumors. in The Journal of biological chemistry 2003 (PubMed)
    Show all 8 references for ABIN2666857

  2. Human Podoplanin Protein expressed in Escherichia coli (E. coli) - ABIN667074 : Wicki, Christofori: The potential role of podoplanin in tumour invasion. in British journal of cancer 2007 (PubMed)
    Show all 2 references for ABIN667074

More Proteins for Podoplanin (PDPN) Interaction Partners

Human Podoplanin (PDPN) interaction partners

  1. interest, LpMab-17 did not bind to monkey PDPN, whereas the homology is 94% between human PDPN and monkey PDPN, indicating that the epitope of LpMab-17 is unique compared with the other anti-PDPN mAbs. The combination of different epitope-possessing mAbs could be advantageous for the PDPN-targeting diagnosis or therapy

  2. podoplanin expression is significantly associated with malignant transformation of chronic lip discoid lupus erythematosus into lip squamous cell carcinoma

  3. the epitope of PMab-21 was identified as Leu44-Glu48, which is corresponding to platelet aggregation-stimulating (PLAG) domain, indicating that Ser61-Ala68 of rabbit PDPN is a more appropriate epitope for immunohistochemistry compared with PLAG domain. PMab-32 could be useful for uncovering the function of rabbit PDPN

  4. NZ-1 inhibits the hPDPN-CLEC-2 (show CLEC1B Proteins) interaction and is also useful for anti-PA tag MAb.The minimum epitope of LpMab-13 was identified as Ala42-Asp49 of hPDPN using Western blot and flow cytometry. The combination of different epitope-possessing MAbs could be advantageous for the hPDPN-targeting diagnosis and therapy

  5. Low PDPN expression is associated with Uterine Cervical Squamous Intraepithelial Lesions.

  6. high tumoral podoplanin expression could independently predict an adverse clinical outcome for ccRCC patients, and it might be useful in future for clinical decision-making and therapeutic developments.

  7. the present results also suggest that podoplanin+ cells can function as stromal cells for blast cell retention in the AML (show RUNX1 Proteins) tumor microenvironment.

  8. We revealed that podoplanin expression in Cancer-associated Fibroblasts was an independent indicator of worse prognosis, irrespective of the expression status of the tumor cells in patients with squamous cell carcinoma of the lung.

  9. High podoplanin expression is associated with lymphatic spread of the breast cancer.

  10. High podoplanin expression is associated with lung metastasis.

Mouse (Murine) Podoplanin (PDPN) interaction partners

  1. Data show that E11/glycoprotein 38(GP38) was up-regulated upon SEMA3A (show SEMA3A Proteins) stimulation, and cyclin-dependent kinase 6 (CDK6 (show CDK6 Proteins)) was down-regulated in a time-dependent manner.

  2. this study uncovers a unique molecular mechanism of lymphangiogenesis in which galectin-8 (show LGALS8 Proteins)-dependent crosstalk among VEGF-C (show VEGFC Proteins), podoplanin and integrin pathways plays a key role.

  3. A reciprocal interaction between CLEC-2 (show CLEC1B Proteins) on megakaryocytes and PDPN on Bone marrow (BM) Fibroblastic reticular cell-like cells contributes to the periarteriolar megakaryopoietic microenvironment in mouse BM.

  4. Data indicate that a mechanism reliant upon blockade of proteasome-mediated E11 destabilization contributes to osteocytogenesis and that this may involve downstream targeting of RhoA (show RHOA Proteins).

  5. it is likely that PDPN, while being dispensable during re-epithelialization, has a crucial role in migration and invasion of transformed keratinocytes.

  6. Report distinct podoplanin-positive stromal cell populations and a novel progenitor subset in chronic liver inflammation and fibrosis.

  7. CLEC-2 (show CLEC1B Proteins) is an adhesive receptor that supports platelet arrest to podoplanin under venous shear. Src (show SRC Proteins)/Syk (show SYK Proteins)-dependent signalling stabilises platelet adhesion to podoplanin.

  8. Alternative NF-kappaB (show NFKB1 Proteins) signaling regulates mTEC differentiation from podoplanin-expressing presursors in the cortico-medullary junction.

  9. These results provide new insight into PDPN phosphorylation dynamics and the role of PDPN in cell motility.

  10. Podoplanin and CLEC-2 (show CLEC1B Proteins) critically drive the formation and integrity of developing cerebral blood vessels.

Cow (Bovine) Podoplanin (PDPN) interaction partners

  1. These results indicated that PDPN gene plays a significant role in the proliferation and maturation of bovine Sertoli cells.

Podoplanin (PDPN) Protein Profile

Protein Summary

This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with Podoplanin Proteins (PDPN)

  • podoplanin (PDPN)
  • podoplanin (Pdpn)
  • podoplanin-like (LOC100738269)
  • AGGRUS protein
  • E11 protein
  • GP36 protein
  • Gp38 protein
  • GP40 protein
  • HT1A-1 protein
  • OTS-8 protein
  • OTS8 protein
  • PA2.26 protein
  • PDPN protein
  • RANDAM-2 protein
  • RTI40 protein
  • T1-alpha protein
  • T1a protein
  • T1A-2 protein
  • T1alpha protein

Protein level used designations for Podoplanin Proteins (PDPN)

podoplanin , PA2.26 antigen , T1-alpha , glycoprotein 36 , glycoprotein, 36-KD , hT1alpha-1 , hT1alpha-2 , lung type I cell membrane associated glycoprotein , lung type-I cell membrane-associated glycoprotein (T1A-2) , aggrus , glycoprotein 38 , transmembrane glycoprotein E11 , E11 antigen epitope , RTI140 , T1A , epithelial cell surface transmembrane protein antigen , pulmonary type I alveolar epithelial cell transmembrane differentiation marker , type I cell 40 kDa protein , gp38 , mucin-type membrane protein gp40

456453 Pan troglodytes
10630 Homo sapiens
14726 Mus musculus
54320 Rattus norvegicus
403886 Canis lupus familiaris
509732 Bos taurus
101787585 Cavia porcellus
768390 Gallus gallus
101112240 Ovis aries
100738269 Sus scrofa
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