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Poliovirus Receptor-Related 4 (PVRL4) ELISA Kits

PVRL4 encodes a member of the nectin family. Additionally we are shipping PVRL4 Antibodies (69) and PVRL4 Proteins (18) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse PVRL4 PVRL4 71740 Q8R007
Anti-Rat PVRL4 PVRL4 498281  
PVRL4 81607 Q96NY8
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Top PVRL4 ELISA Kits at

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 51 pg/mL 125.00-8000 pg/mL 96 Tests Log in to see 9 to 11 Days

More ELISA Kits for PVRL4 Interaction Partners

Mouse (Murine) Poliovirus Receptor-Related 4 (PVRL4) interaction partners

  1. Novel type of cell adhesion apparatus is mediated by Nectin-1 (show PVRL1 ELISA Kits) and Nectin-4. It's implicated in prolactin receptor (show PRLR ELISA Kits) signaling for mammary gland development.

  2. Pvrl1 (show PVRL1 ELISA Kits) is a bona fide target gene of the transcription factor p63 (show CKAP4 ELISA Kits), whereas Pvrl4 regulation is linked to epidermal differentiation and is under Irf6 (show IRF6 ELISA Kits)

  3. Mouse PVRL4 functions less efficiently as a receptor for measles virus than the human homologue.

  4. Ectodermal dysplasia-syndactyly syndrome is the second known "nectinopathy" caused by mutations in a nectin (show PVRL1 ELISA Kits) adhesion molecule (show NCAM1 ELISA Kits).

Human Poliovirus Receptor-Related 4 (PVRL4) interaction partners

  1. ADAM17 (show ADAM17 ELISA Kits) and ADAM10 (show ADAM10 ELISA Kits) cleave Nectin-4 and release soluble Nectin-4 (sN4).

  2. The data presented in this study suggested that nectin-4 may be a therapeutic target for systemic lupus erythematous through affecting the cell apoptosis

  3. Nectin-4 is critical for gallbladder cancer cell progression via PI3K/AKT pathway activation of Rac1.

  4. Nectin-4 expression, when compared with control group, was higher in endometriotic lesions of patients having ovarian endometriosis and peritoneal endometriosis. This difference was significant in the endometrium of patients having endometriosis.

  5. Transformation of breast cancer cells is dependent on PVRL4.

  6. Nectin-4 is a significant prognostic predictor, and may play a critical role in pancreatic cancer. Nectin-4 may be novel therapeutic target for pancreatic cancer.

  7. In airway epithelial cells, measles virus spread requires the nectin-4/afadin (show MLLT4 ELISA Kits) complex and is based on cytoplasm transfer between columnar cells.

  8. The present study described clinical investigation of the EDSS1 identified in a large consanguineous family; DNA sequence analysis revealed a novel homozygous nonsense mutation (181C>T, p.Asp61*) in the PVRL4 gene.

  9. Ovarian tissue expression and serum nectin 4 appear to be potential markers in ovarian cancer.

  10. Authors show that the same key residues in the BC and FG loops of nectin-4 govern binding to the measles virus attachment protein hemagglutinin (show HA ELISA Kits) (H) and cell entry, nectin-4 homodimerization, and heterodimerization with nectin-1 (show PVRL1 ELISA Kits).

PVRL4 Antigen Profile

Antigen Summary

This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

Gene names and symbols associated with PVRL4

  • poliovirus receptor-related 4 (PVRL4) antibody
  • poliovirus receptor-related 4 (pvrl4) antibody
  • poliovirus receptor-related 4 (LOC100348580) antibody
  • poliovirus receptor-related 4 (Pvrl4) antibody
  • 1200017F15Rik antibody
  • EDSS1 antibody
  • LNIR antibody
  • nectin-4 antibody
  • PRR4 antibody
  • PVRL4 antibody
  • RGD1559826 antibody
  • si:ch211-155e24.1 antibody

Protein level used designations for PVRL4

poliovirus receptor-related 4 , poliovirus receptor-related protein 4-like , ig superfamily receptor LNIR , nectin 4 , nectin-4 , poliovirus receptor-related protein 4 , Ig superfamily receptor LNIR

609931 Canis lupus familiaris
794920 Danio rerio
100032730 Monodelphis domestica
100066309 Equus caballus
100348580 Oryctolagus cuniculus
100435072 Pongo abelii
71740 Mus musculus
498281 Rattus norvegicus
81607 Homo sapiens
507718 Bos taurus
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