Poly A Specific Ribonuclease (PARN) ELISA Kits

The protein encoded by PARN is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. Additionally we are shipping PARN Antibodies (66) and PARN Proteins (15) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
PARN 5073 O95453
Anti-Rat PARN PARN 360464  
PARN 74108 Q8VDG3
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Top PARN ELISA Kits at antibodies-online.com

Showing 3 out of 12 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.27 ng/mL 0.78-50 ng/mL 96 Tests Log in to see 13 to 16 Days
Mouse 35-10.000 pg/mL 96 Tests Log in to see 2 to 3 Days
  96 Tests Log in to see 15 to 18 Days

More ELISA Kits for PARN Interaction Partners

Human Poly A Specific Ribonuclease (PARN) interaction partners

  1. poly(A)-specific ribonuclease (PARN) participates in steps leading to 18S pre-rRNA maturation in human cells

  2. we found a polyadenylation-dependent 3' end maturation pathway for the human telomerase RNA that relies on the nuclear poly(A)-binding protein PABPN1 (show PABPN1 ELISA Kits) and the poly(A)-specific RNase PARN.

  3. PARN increased telomerase RNA component levels by deadenylating telomerase RNA component, thereby limiting its degradation by EXOSC10.

  4. Large monoallelic mutations of PARN can cause developmental/mental illness. Biallelic PARN mutations cause severe bone marrow failure and central hypomyelination.

  5. results highlight the clinical significance of PARN and NOC (show CCRN4L ELISA Kits) on the survival in SCC (show CYP11A1 ELISA Kits) diagnosed patients.

  6. Mutations in the PARN gene cause dyskeratosis congenital.

  7. The results indicate that the cellular level of miR (show MLXIP ELISA Kits)-122 is determined by the balance between the opposing effects of GLD-2 (show PAPD4 ELISA Kits) and PARN/CUGBP1 (show CELF1 ELISA Kits) on the metabolism of its 3'-terminus.

  8. 3 families with dyskeratosis congenita had key domain mutations in PARN shortening telomeres, reducing deadenylation, and downregulating TERC, DKC1 (show DKC1 ELISA Kits), RTEL1 (show RTEL1 ELISA Kits), and TERF1 (show TERF1 ELISA Kits).

  9. PARN and RTEL1 (show RTEL1 ELISA Kits) mutation carriers had shortened leukocyte telomere lengths.

  10. poly(A)-specific ribonuclease (PARN) was upregulated in gastric tumor tissues and gastric cancer cell lines MKN28 and AGS (show JAG1 ELISA Kits).

Mouse (Murine) Poly A Specific Ribonuclease (PARN) interaction partners

  1. these data indicate that PARN modulates decay of a defined set of mRNAs in mammalian cells and implicate this deadenylase in coordinating control of genes required for cell movement.

  2. poly(A) polymerase (show PAPOLA ELISA Kits) Gld2 (show PAPD4 ELISA Kits), deadenylase PARN, and translation inhibitory factor neuroguidin (Ngd (show NGDN ELISA Kits)) are components of a dendritic CPEB (show CPEB1 ELISA Kits)-associated polyadenylation apparatus

  3. Solution structures of the cap-binding domain of mouse PARN with and without the m(7)GpppG cap analog reveal a novel cap-binding mode.

  4. A modeled PARN, which shows that the RRM domain from one subunit and the R3H domain from the other subunit enclose the active site.

PARN Antigen Profile

Antigen Summary

The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PARN

  • poly(A)-specific ribonuclease (parn) antibody
  • poly(A)-specific ribonuclease (PARN) antibody
  • poly(A)-specific ribonuclease (Parn) antibody
  • poly(A)-specific ribonuclease (deadenylation nuclease) (parn) antibody
  • poly(A)-specific ribonuclease (deadenylation nuclease) (Parn) antibody
  • 1200003I18Rik antibody
  • DAN antibody
  • parn-A antibody
  • RGD1565449 antibody
  • xparn antibody
  • zgc:56067 antibody

Protein level used designations for PARN

deadenylating nuclease , deadenylation nuclease , poly(A)-specific ribonuclease (deadenylation nuclease) , poly(A)-specific ribonuclease PARN , polyadenylate-specific ribonuclease

394409 Xenopus laevis
5073 Homo sapiens
479839 Canis lupus familiaris
524155 Bos taurus
360464 Rattus norvegicus
100172259 Pongo abelii
791461 Danio rerio
74108 Mus musculus
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