Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
The product of P2RX7 belongs to the family of purinoceptors for ATP. Additionally we are shipping P2RX7 Antibodies (119) and P2RX7 Proteins (7) and many more products for this protein.
Showing 6 out of 12 products:
Blockade of the P2X7 receptor reduces cyst formation via ERK (show MAPK1 ELISA Kits)-dependent pathways in a zebrafish model of polycystic kidney disease.
there is a relationship between the elevated expression of P2X3 (show P2RX3 ELISA Kits) receptor and P2X7 receptor in peripheral blood leukocytes and high serum epinephrine and norepinephrine levels in hyperthyroidism patients.
a pivotal role of P2X7 receptor-pannexin-1 (show PANX1 ELISA Kits) in oxysterols toxicity in retinal cells
significant upregulation of P2X7R and increased IL-1beta (show IL1B ELISA Kits) release seems to be a particular phenomenon in patients with neuropathic pain
We identified potential nuclear and membrane biomarkers (increased expression of ZO-1 (show TJP1 ELISA Kits), caveolin-1 (show CAV1 ELISA Kits) and P2X7 receptor) of risks for placenta and pregnancy
The association between independent P2X7R polymorphisms with stress fracture prevalence supports the role of a genetic predisposition in the development of stress fracture
these data indicate that activation of EGFR (show EGFR ELISA Kits) enhanced the expression of P2X7R in neuroblastoma (show ARHGEF16 ELISA Kits) cells lacking trophic support, being PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits)/PKC signaling pathway and Sp1 (show PSG1 ELISA Kits) mediating this pro-survival outcome
Result suggest the positive correlation between purinergic receptor P2X 7 (P2X7R) and T-complex protein 1 (TCP-1) in lymphoma patients.
A gain-of-function mutation in P2X7R associated with autoimmune disease caused enhanced TG2 (show TGM2 ELISA Kits) externalization from cells, and this correlated with increased pore activity.
pancreatic ductal adenocarcinoma cell lines overexpress P2X7R and the receptor plays crucial roles in cell survival, migration and invasion.
P2X7 SNPs, 1513A>C and -762T>C, may be associated with the susceptibility to tuberculosis.
For the inflammasome-dependent IL-1beta (show IL1B ELISA Kits) release, bovine monocytes require ATP in addition to a primary stimulus. This IL-1beta (show IL1B ELISA Kits) release depends on potassium efflux, but, in contrast to human and murine monocytes, does not require calcium influx or generation of reaction oxygen and is independent of the P2X7 receptor.
P2X7R stimulation in macrophages is able to release potent anti-inflammatory proteins, such as Annexin A1 (show ANXA1 ELISA Kits), independently of their polarization state suggesting for first time a potential role for P2X7R during resolution of the inflammation and not linked to the release of pro-inflammatory cytokines.
These results indicate that activation of Panx1 (show PANX1 ELISA Kits) and P2X7 R are required for apoptotic osteocytes in fatigued bone to trigger RANKL (show TNFSF11 ELISA Kits) production in neighboring bystander osteocytes and implicate ATP as an essential signal mediating this process.
A role for post-transcriptional regulation of the P2X7R in epilepsy
We also demonstrate extracellular ATP participates in regulation of inflammatory responses of colitis, through P2 x 7 receptor and inflammasome and NFkappaB signaling.
we reveal that neuronal vulnerability to ATP depends on the expression level of P2X7R
Activation of P2X7 by ATP induced the release of TNFalpha (show TNF ELISA Kits) from microglia which protected neurons from NMDA-induced excitotoxicity, might also account for neuroprotective properties of valproic acid
Data provide mechanistic insights into the role of KHG26792 in the inhibition of TNF-alpha (show TNF ELISA Kits) produced via purinergic receptor P2X7 receptor-mediated activation of NFAT (show NFATC1 ELISA Kits) and MAPK (show MAPK1 ELISA Kits) pathways in adenosine triphosphate-treated BV-2 cells.
Results suggest that P2X7R is an important activator of the immune response that leads to type 1 diabetes.
P2X7R plays a role in the neuroinflammation in a model of mania.
Data show that T-complex protein 1 (TCP-1) may be a crucial downstream molecule of purinergic receptor P2X 7 (P2X7R) and plays a role in lymphoid neoplasm metastasis.
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.
P2X purinoceptor 7
, purinergic receptor P2X, ligand-gated ion channel, 7
, p2X purinoceptor 7-like
, ATP receptor
, P2X7 receptor
, P2Z receptor
, purinergic receptor P2X7 variant A
, P2X7 purinoceptor
, purinergic receptor P2X7