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Rabphilin 3A Homolog (Mouse) Proteins (RPH3A)

Exocytosis of neurotransmitters and hormones is fundamental to synaptic neurotransmission and cell-cell communication. Additionally we are shipping Rabphilin 3A Homolog (Mouse) Antibodies (70) and Rabphilin 3A Homolog (Mouse) Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RPH3A 171039 P47709
RPH3A 19894 P47708
RPH3A 22895 Q9Y2J0
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Top Rabphilin 3A Homolog (Mouse) Proteins at

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 59 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 59 Days
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days

RPH3A Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Mouse (Murine)

Human ,

More Proteins for Rabphilin 3A Homolog (Mouse) (RPH3A) Interaction Partners

Mouse (Murine) Rabphilin 3A Homolog (Mouse) (RPH3A) interaction partners

  1. Rph3A interacts with GluN2A (show GRIN2A Proteins) and PSD-95 (show DLG4 Proteins) forming a complex that regulates NMDARs stabilization at postsynaptic membranes.

  2. a possible role in glo (show RAB3A Proteins)merulopathies

  3. Our results indicate that a decrease in mRNA levels underlie the depletion of protein levels of rabphilin 3A, and we suggest that this reduction may be involved in causing impaired synaptic transmission in R6/1 mice.

  4. rabphilin, by interacting with alpha-actinin, organizes the cell cytoskeleton to facilitate granule localization within F-actin-rich regions

  5. Binding of rabphilin to SNAP-25 regulates exocytosis of synaptic vesicles after the readily releasable pool has either been physiologically exhausted by use-dependent depression, or has been artificially depleted by deletion of synaptobrevin.

  6. Our results suggest that rabphilin, a protein present in presynaptic terminals, could play a role in the late phase of L-LTP (show SCP2 Proteins).

Human Rabphilin 3A Homolog (Mouse) (RPH3A) interaction partners

  1. Rabphilin-3A is a major autoantigen in Lymphocytic infundibulo-neurohypophysitis (LINH). Autoantibodies to rabphilin-3A may serve as biomarker for the diagnosis of LINH and be useful for the differential diagnosis of Central diabetes insipidus.

  2. rabphilin 3A loss correlated with dementia severity, cholinergic deafferentation, and increased beta-amyloid concentrations

  3. Structural insights into the Ca2 (show CA2 Proteins)+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1 (show SYT1 Proteins).

  4. Rabphilin-3A and Rab3A (show RAB3A Proteins) are present in normal mouse, rat, and human kidneys, with an exclusively glomerular expression and a comma-like pattern of positivity along the glomerular capillary wall, suggestive for podocyte staining.

  5. Since rab3a participates in the docking and fusion of synaptic vesicles, and rabsa binding to alpha-synuclein is increased in Lewy body disease (LBD), it can be suggested that exocytosis of neurotransmitters may be impaired in LBD.

  6. We found a reduction in rabphilin 3a, a protein involved in vesicle docking and recycling, in Huntington disease (show HTT Proteins)[HD] brains of grade III and IV. A deficient pre-synaptic transmitter release may underlie some symptoms of HD.

Rabphilin 3A Homolog (Mouse) (RPH3A) Protein Profile

Protein Summary

Exocytosis of neurotransmitters and hormones is fundamental to synaptic neurotransmission and cell-cell communication. RAB3A (MIM 179390) is a small G protein that is thought to act at late stages of exocytosis, and RPH3A is a RAB3A effector (Lin et al., 2007

Gene names and symbols associated with RPH3A

  • Rabphilin (Rph)
  • rabphilin-3a (Smp_145120)
  • rabphilin-3A (Tsp_00335)
  • rabphilin 3A (Rph3a)
  • rabphilin 3A homolog (rph3a)
  • rabphilin 3A homolog (mouse) (RPH3A)
  • 2900002P20Rik protein
  • AU022689 protein
  • AW108370 protein
  • CG11556 protein
  • Dmel\\CG11556 protein
  • exophilin-1 protein

Protein level used designations for RPH3A

CG11556-PA , CG11556-PB , CG11556-PC , CG11556-PD , Rph-PA , Rph-PB , Rph-PC , Rph-PD , dm-rabphilin , rabphilin , rabphilin-3A , rabphilin-3a , exophilin-1 , rabphilin 3A homolog , Doc2 family , likely ortholog of mouse rabphilin 3A

32002 Drosophila melanogaster
8354342 Schistosoma mansoni
10901575 Trichinella spiralis
171039 Rattus norvegicus
19894 Mus musculus
446587 Xenopus laevis
22895 Homo sapiens
611038 Canis lupus familiaris
282044 Bos taurus
416886 Gallus gallus
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