Ras Homolog Gene Family, Member U Proteins (RHOU)

RHOU encodes a member of the Rho family of GTPases. Additionally we are shipping RHOU Antibodies (41) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RHOU 58480 Q7L0Q8
RHOU 69581 Q9EQT3
RHOU 781044 A5D7J5
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Top RHOU Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days

RHOU Proteins by Origin and Source

Origin Expressed in Conjugate

Mouse (Murine)

Cow (Bovine)

More Proteins for Ras Homolog Gene Family, Member U (RHOU) Interaction Partners

Human Ras Homolog Gene Family, Member U (RHOU) interaction partners

  1. PAK4 (show PAK4 Proteins) and RhoU cooperate to drive adhesion turnover and promote cell migration.

  2. Data indicate that upregulated miR (show MLXIP Proteins)-126 upon coxsackievirus B3 (CVB3) infection targets SPRED1 (show SPRED1 Proteins), LRP6 (show LRP6 Proteins), and WRCH1 genes, mediating cross-talk between ERK1/2 and Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) pathways, and thus promoting viral replication.

  3. multiple upstream signals may converge on Wrch1 directly through its SH3 domain-binding properties

  4. results indicate that NOTCH1 (show NOTCH1 Proteins) mutation stimulates T-cell acute lymphoblastic leukaemia cell migration through RhoU upregulation that could contribute to the leukaemia cell dissemination

  5. data suggest a unique regulatory mechanism by which RhoU interaction with SH3 adaptor proteins might serve to integrate growth factor receptor (show RYK Proteins) signaling with RhoU activatio

  6. A screen for Wrch-1 binding-partners identified the novel RhoGAP protein (show ARHGAP26 Proteins), ARHGAP30, as a Wrch-1 interactor.

  7. Studies revealed a requirement for serum-stimulated tyrosine phosphorylation of Wrch1 at residue Y254 within its C-terminal membrane targeting domain, mediated by the nonreceptor tyrosine kinase (show TXK Proteins) Src (show SRC Proteins).

  8. Down regulation of WRCH1 by estradiol in breast cancer and altered expression of WRCH1 is associated with other cancers

  9. G28K cDNA encodes a protein of 258 amino acids with homology to the cell division cycle 42/G25K protein; this gene is located at 1q42.11-q42.3; G28K was abundantly expressed in the stomach and the small intestine

  10. These data suggest that Wrch-1 regulates cell migration by multiple mechanisms: on the one hand Wrch-1 controls focal adhesions by regulating myosin light chain and on the other hand Wrch-1 stimulates the activation of Akt (show AKT1 Proteins) and JNK (show MAPK8 Proteins).

Mouse (Murine) Ras Homolog Gene Family, Member U (RHOU) interaction partners

  1. Rhou activity maintains the epithelial architecture of the endoderm progenitors, and its downregulation accompanies the transition of the columnar epithelium in the embryonic foregut to a multilayered cell sheet during organ formation.

  2. G28K was differentially expressed in the small intestines; interstitial cells of Cajal within the small intestine expressed mRNA for G28K; downregulated in the jejunum of W/W V mice.

  3. Wrch-1 membrane association, subcellular localization, and biological activity are mediated by a novel membrane-targeting mechanism distinct from that of Cdc42 (show CDC42 Proteins) and other isoprenylated Rho family GTPases

  4. Wrch1 collaborates with FAK2 (show PTK2B Proteins) and Src (show SRC Proteins) in regulating cytoskeletal dynamics.

RHOU Protein Profile

Protein Summary

This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus.

Gene names and symbols associated with RHOU

  • ras homolog gene family, member U (RHOU)
  • ras homolog gene family, member U (rhou)
  • ras homolog family member U (RHOU)
  • ras homolog gene family, member U (Rhou)
  • 2310026M05Rik protein
  • AI182090 protein
  • Arhu protein
  • CDC42L1 protein
  • DJ646B12.2 protein
  • fJ646B12.2 protein
  • G28K protein
  • hG28K protein
  • mG28K protein
  • MGC107947 protein
  • WRCH-1 protein
  • WRCH1 protein

Protein level used designations for RHOU

ras homolog gene family, member U , 2310026M05Rik , CDC42-like GTPase 1 , GTP-binding protein SB128 , GTP-binding protein like 1 , Ryu GTPase , ras-like gene family member U , rho GTPase-like protein ARHU , rho-related GTP-binding protein RhoU , wnt-1 responsive Cdc42 homolog 1 , Ras-like protein member U , Wnt1 responsive Cdc42 homolog

428589 Gallus gallus
479211 Canis lupus familiaris
548469 Xenopus (Silurana) tropicalis
695385 Macaca mulatta
58480 Homo sapiens
69581 Mus musculus
781044 Bos taurus
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