anti-Retinal Degeneration 3 (RD3) Antibodies

RD3 encodes a retinal protein that is associated with promyelocytic leukemia-gene product (PML) bodies in the nucleus. Additionally we are shipping RD3 Proteins (3) and RD3 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RD3 343035 Q7Z3Z2
Anti-Mouse RD3 RD3 74023 Q8BRE0
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Top anti-RD3 Antibodies at

Showing 3 out of 5 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-RD3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human brain 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated WB Western Blot: RD3 Antibody [NBP1-55461] - Titration: 0.2-1 ug/ml, Positive Control: Human brain. 100 μL Log in to see 8 to 11 Days

RD3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality

Dog (Canine)

Top referenced anti-RD3 Antibodies

  1. Dog (Canine) Polyclonal RD3 Primary Antibody for WB - ABIN2774124 : Friedman, Chang, Kannabiran, Chakarova, Singh, Jalali, Hawes, Branham, Othman, Filippova, Thompson, Webster, Andréasson, Jacobson, Bhattacharya, Heckenlively, Swaroop: Premature truncation of a novel protein, RD3, exhibiting subnuclear localization is associated with retinal degeneration. in American journal of human genetics 2006 (PubMed)

More Antibodies against RD3 Interaction Partners

Human Retinal Degeneration 3 (RD3) interaction partners

  1. Re-expressing RD3 in metastatic site-derived aggressive cells reverted their metastatic potential both in vitro and in vivo. Conversely muting RD3 in neuroblastoma (show ARHGEF16 Antibodies) cells not only heightened invasion/migration but also dictated aggressive disease with metastasis.

  2. This study reports the results of an international study aimed at delineating the clinical and molecular spectrum of RD3 mutations in retinal dystrophies.

  3. Mutations in RD3 are a very rare cause of Leber's congenital amaurosis (LCA (show CLTA Antibodies)) associated with an extremely severe form of retinal dystrophy (show MERTK Antibodies).

  4. RD3 suppresses the basal catalytic activity of guanylyl cyclase activating proteins (GCAP (show ALPPL2 Antibodies)) in a noncompetitive manner.

  5. Identification and sequence analysis of C1orf36.

  6. the retinopathy-associated RD3 protein is part of subnuclear protein complexes involved in diverse processes, such as transcription and splicing.

Mouse (Murine) Retinal Degeneration 3 (RD3) interaction partners

  1. the main RetGC (show GUCY2D Antibodies)-binding interface on RD3 required for the negative regulation of the cyclase localizes to the Lys (show LYZ Antibodies)(87)-Leu(122) region.

  2. Direct association between RD3 and GCAP1 is important for GC1 targeting.

  3. Studies indicate that RD3 plays an essential role in the exit of guanylate cyclase from the endoplasmic reticulum and its trafficking to photoreceptor outer segments.

  4. Changes in gene expression associated with photoreceptor degeneration in the rd3 mouse model of Leber congenital amaurosis (LCA (show CLTA Antibodies)) type 12, are characterized.

  5. photoreceptor degeneration in the rd3 mouse, rcd2 dog, and LCA12 patients is caused by impaired RD3-mediated guanylate cyclase expression and trafficking

  6. Rd3 is preferentially expressed in the retina and exhibits increasing expression through early postnatal development.

RD3 Antigen Profile

Protein Summary

This gene encodes a retinal protein that is associated with promyelocytic leukemia-gene product (PML) bodies in the nucleus. Mutations in this gene cause Leber congenital amaurosis type 12, a disease that results in retinal degeneration. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with RD3

  • retinal degeneration 3 (RD3) antibody
  • retinal degeneration 3 (Rd3) antibody
  • 3322402L07Rik antibody
  • C1orf36 antibody
  • LCA12 antibody
  • rd-3 antibody
  • rd3 antibody

Protein level used designations for RD3

protein RD3 , retinal degeneration protein 3

343035 Homo sapiens
74023 Mus musculus
Selected quality suppliers for anti-RD3 (RD3) Antibodies
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