Ring Finger Protein 115 Proteins (RNF115)

Acts as an E2-dependent E3 ubiquitin-protein ligase. Additionally we are shipping RNF115 Antibodies (39) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RNF115 27246 Q9Y4L5
RNF115 67845 Q9D0C1
Rat RNF115 RNF115 362002  
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Top RNF115 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days

RNF115 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

More Proteins for Ring Finger Protein 115 (RNF115) Interaction Partners

Human Ring Finger Protein 115 (RNF115) interaction partners

  1. Specifically, BCA2 serves as an E3 SUMO ligase in the SUMOylation of IkappaBalpha (show NFKBIA Proteins), which in turn enhances the sequestration of NF-kappaB (show NFKB1 Proteins) components in the cytoplasm. Since HIV-1 utilizes NF-kappaB (show NFKB1 Proteins) to promote proviral transcription, the BCA2-mediated inhibition of NF-kappaB (show NFKB1 Proteins) significantly decreases the transcriptional activity of HIV-1.

  2. BCA2 functions as an antiviral factor that targets HIV-1 Gag for degradation, impairing virus assembly and release.

  3. BCA2 is an endogenous inhibitor of AMPK (show PRKAA1 Proteins) activation in breast cancer cells and BCA2 inhibition increases the efficacy of metformin.

  4. BCA2, a potential oncogenic E3 ubiquitin ligase (show MUL1 Proteins), promotes breast cancer cell proliferation partially through targeting p21 (show CDKN1A Proteins) for ubiquitination and proteasomal degradation.

  5. RNF126 and Rabring7 play a role in the ubiquitin-dependent sorting and downregulation of membrane receptors.

  6. High BCA2 expression is associated with renal oncocytoma.

  7. BCA2 is therefore a newly identified transcriptional target of estrogen receptor (show ESR1 Proteins).

  8. Rabring7 stimulates c-Myc (show MYC Proteins) degradation via mono-ubiquitination of MM-1 (show PFDN5 Proteins)

  9. BCA2 accelerates the internalization and degradation of viral particles following their tethering to the cell surface and is a co-factor or enhancer for the tetherin (show BST2 Proteins)-dependent restriction of HIV-1 release from infected cells.

  10. BCA2 E3 ligase is coregulated with estrogen receptor (show ESR1 Proteins) and plays a role in the regulation of epidermal growth factor receptor (EGF-R (show EGFR Proteins)) trafficking

Mouse (Murine) Ring Finger Protein 115 (RNF115) interaction partners

  1. Rabring7 plays crucial roles as a Rab7 (show RAB7A Proteins) target protein in vesicle traffic to late endosome/lysosome and lysosome biogenesis (rabring7)

RNF115 Protein Profile

Protein Summary

Acts as an E2-dependent E3 ubiquitin-protein ligase. May be involved in endocytic trafficking.

Gene names and symbols associated with RNF115

  • ring finger protein 115 (RNF115)
  • ring finger protein 115 (Rnf115)
  • 2610028E05Rik protein
  • AU042696 protein
  • BCA2 protein
  • Zfp364 protein
  • ZNF364 protein

Protein level used designations for RNF115

E3 ubiquitin-protein ligase RNF115 , rabring 7 , zinc finger protein 364 , Rab7-interacting RING finger protein , Rabring7 , RING finger protein 115 , Rabring 7

27246 Homo sapiens
612818 Canis lupus familiaris
67845 Mus musculus
362002 Rattus norvegicus
614061 Bos taurus
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