SRY (Sex Determining Region Y)-Box 17 (SOX17) ELISA Kits

SOX17 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Additionally we are shipping SOX17 Antibodies (90) and SOX17 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SOX17 64321 Q9H6I2
Anti-Rat SOX17 SOX17 312936  
Anti-Mouse SOX17 SOX17 20671 Q61473
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More ELISA Kits for SOX17 Interaction Partners

Human SRY (Sex Determining Region Y)-Box 17 (SOX17) interaction partners

  1. Dedifferentiation of fibroblasts to CD34 (show CD34 ELISA Kits)(+) progenitor cells gives rise to endothelial cells and erythroblasts in a SOX17-dependent manner.

  2. Study extracted and analyzed the experimentally validated 3D models of SOX17-HMG (show SSRP1 ELISA Kits) domain and beta-catenin (show CTNNB1 ELISA Kits); the molecular level disturbance in the two essential human proteins upon M76A and G103R mutation of SOX17, which further hampers the cell signaling phenomena for the human cytological developments beginning from gastrulation and endoderm formation.

  3. SOX17 promoter is highly methylated in primary tumors and in corresponding plasma samples both in operable and advanced non-small cell lung cancer.

  4. The definitive endoderm and foregut endoderm differentiation capabilities of Wnt (show WNT2 ELISA Kits) pathway-modulated cells were determined based on the expression levels of the endodermal transcription factors SOX17 and FOXA2 (show FOXA2 ELISA Kits) and those of the transcription activator GATA4 (show GATA4 ELISA Kits) and the alpha-fetoprotein (AFP (show AFP ELISA Kits)) gene, respectively.

  5. Knockdown of OCT4 (show POU5F1 ELISA Kits) during differentiation inhibits mesendoderm formation and removal of the H3K27me3 mark from the SOX17 promoter, suggesting that OCT4 (show POU5F1 ELISA Kits) acts to induce removal of the Polycomb2 complex.

  6. high expression of the Sox17 associated pathway in medium and small arteries indicates that Brain arteriovenous malformation vessels are intrinsically active

  7. SOX17 demethylation induced miR (show MLXIP ELISA Kits)-371-5p expression and consequently suppressed its direct target SOX2 (show SOX2 ELISA Kits). A novel mechanism of the SOX17/miR (show MLXIP ELISA Kits)-371-5p/SOX2 (show SOX2 ELISA Kits) axis is involved in the regulation of EMT (show ITK ELISA Kits), stemness and metastasis.

  8. Decreased expression of SOX17 is associated with tumor progression in breast cancer.

  9. In this study, oligodendroglioma patients with 1p/19q LOH and Sox17 protein expression had a better prognosis.

  10. SOX17 might play a role in the development of Ovarian Cancer, and may be a therapeutic target in OC.

Zebrafish SRY (Sex Determining Region Y)-Box 17 (SOX17) interaction partners

  1. Targeted knockdown of Sox17 and Chd (show CHRD ELISA Kits) in dorsal forerunner cells led to aberrant Left-Right (L-R) asymmetry establishment, as visualized by the expression of southpaw and lefty (show LEFTY2 ELISA Kits), and heart and pancreas placement in the embryo.

  2. knockout of dusp4 (show DUSP4 ELISA Kits) revealed a specific loss of sox17, establishing a new class of endoderm specification defect

  3. Results describe sox17 cis (show CISH ELISA Kits)-regulatory elements, and examine the specific input predictions of the gene regulatory networks.

Mouse (Murine) SRY (Sex Determining Region Y)-Box 17 (SOX17) interaction partners

  1. Sox17 disruption in epithelial and stromal compartments led to inhibition of endometrial adenogenesis and a loss of reproductive capacity. Epithelium-specific Sox17 disruption resulted in normal adenogenesis although reproductive capacity remained impaired. Non-epithelial, Sox17-positive cells are necessary for adenogenesis and endometrial glands require Sox17 to properly function.

  2. SOX-17 transcription factor is indispensable in developmental angiogenesis and as a positive feedback regulator of VEGF signaling.

  3. findings indicate the role of Sry (show SRY ELISA Kits)-related HMG (show SSRP1 ELISA Kits) box gene-17 (Sox17) in uterine receptivity to embryo implantation.

  4. combined deletion of Sox7 (show SOX7 ELISA Kits), Sox17, and Sox18 (show SOX18 ELISA Kits) at the onset of retinal angiogenesis leads to a dense capillary plexus with a nearly complete loss of radial arteries and veins, whereas the presence of a single Sox17 allele largely restores arterial identity

  5. Sox17 inhibition of Runx1 (show RUNX1 ELISA Kits) and Gata2 (show GATA2 ELISA Kits) maintains endothelial fate in endothelial-to-haematopoietic transition

  6. Sox17 deficiency in mouse can induce intracranial aneurysm under hypertensive conditions, suggesting Sox17 deficiency as a potential genetic factor for IA formation.

  7. These results identify a novel role for Sox17 in adult liver as a modulator of the metabolic adaptation to fasting.

  8. the transcription factor SOX17, which is activated in prospective definitive endoderm cells before intercalation, is necessary for gut (show GUSB ELISA Kits) endoderm morphogenesis and the assembly of the basement membrane that separates gut (show GUSB ELISA Kits) endoderm from mesoderm.

  9. Hhex (show HHEX ELISA Kits) and Cer1 (show CER1 ELISA Kits) are indispensable components of the Sox17 pathway for cardiopoiesis.

  10. A regulatory network, incluing Sox17 and the retinoic acid receptor (show RARA ELISA Kits), controls nephrocan expression and midgut patterning.

SOX17 Antigen Profile

Antigen Summary

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.

Gene names and symbols associated with SOX17

  • SRY (sex determining region Y)-box 17 beta, gene 1 (sox17b.1) antibody
  • SRY (sex determining region Y)-box 17 alpha (sox17a) antibody
  • SRY (sex determining region Y)-box 17 (SOX17) antibody
  • similar to SRY-box 17 (SOX17) antibody
  • SRY (sex determining region Y)-box 17 beta, gene 2 (sox17b.2) antibody
  • SRY-box containing gene 17 (sox17) antibody
  • sox7/17 protein (sox7/17) antibody
  • SRY (sex determining region Y)-box 17 (Sox17) antibody
  • SRY-box containing gene 17 (Sox17) antibody
  • Sox antibody
  • sox7/17 antibody
  • SOX17 antibody
  • sox17-alpha antibody
  • sox17-beta antibody
  • Sox17alpha antibody
  • sox17beta antibody
  • tSox17alpha antibody
  • tSox17beta antibody
  • VUR3 antibody
  • Xsox17 antibody
  • Xsox17-alpha antibody
  • Xsox17-beta antibody
  • xsox17a antibody
  • Xsox17alpha antibody
  • xSox17alpha1 antibody
  • xSox17alpha2 antibody

Protein level used designations for SOX17

SRY (sex determining region Y)-box 17 beta, gene 1 , Transcription factor Sox-17-beta.1 , HMG box transcription factor Sox17-beta , SRY (sex determining region Y)-box 17-beta.1 , HMG box transcription factor Sox17-alpha , sox17 alpha , transcription factor Sox-17-alpha , SRY (sex determining region Y)-box 17 , similar to SRY-box 17 , SRY (sex determining region Y)-box 17 beta, gene 2 , Transcription factor Sox-17-beta.2 , SRY (sex determining region Y)-box 17-beta.2 , SRY-box containing gene 17 , sox7/17 protein , SRY-related HMG-box transcription factor SOX17 , transcription factor SOX-17 , HMG transcription factor SOX17 , SRY-box 17

394440 Xenopus (Silurana) tropicalis
395066 Xenopus (Silurana) tropicalis
694097 Macaca mulatta
695494 Macaca mulatta
740572 Pan troglodytes
100038235 Xenopus (Silurana) tropicalis
100304455 Oryzias latipes
100591356 Nomascus leucogenys
100303486 Saccoglossus kowalevskii
64321 Homo sapiens
486955 Canis lupus familiaris
312936 Rattus norvegicus
428534 Gallus gallus
534010 Bos taurus
30544 Danio rerio
20671 Mus musculus
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