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Scinderin Proteins (SCIN)

SCIN is a Ca(2+)-dependent actin-severing and -capping protein (Zunino et al., 2001 [PubMed 11568009]).[supplied by OMIM, May 2010].. Additionally we are shipping Scinderin Antibodies (18) and Scinderin Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SCIN 85477 Q9Y6U3
SCIN 20259 Q60604
Rat SCIN SCIN 298975  
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Top Scinderin Proteins at

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

SCIN Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

More Proteins for Scinderin (SCIN) Interaction Partners

Human Scinderin (SCIN) interaction partners

  1. High levels of SCIN expression in gastric cancer tissue correlate with poor prognosis of patients. SCIN enhances the invasion and metastasis of GC cells through activating the Cdc42 (show CDC42 Proteins) pathway to increase the formation of filopodia.

  2. Suppression of scinderin impairs proliferation and migration of gastric cancer SGC7901 cells and attenuates its epithelialmesenchymal transition process.

  3. SCIN plays an important role in lung carcinoma cell proliferation

  4. These results suggest that SCIN plays an important role in the proliferation of prostate cancer cells and lentivirus-mediated inhibition of SCIN expression may be a potential therapeutic method for the treatment of prostate cancer

  5. Scinderin expression does not correlate with prognosis in head and neck cancer.

  6. calcium binding to the N terminus of adseverin dominates the activation process to expose the F-actin binding site on A2

Mouse (Murine) Scinderin (SCIN) interaction partners

  1. Adseverin knockdown also suppressed the RANKL (show TNFSF11 Proteins)-mediated induction of nuclear factor of activated T-cell (show NFATC3 Proteins) c1 (NFATc1 (show NFATC1 Proteins)), which is a key transcription factor in osteoclastogenesis.

  2. Data indicate that adseverin (Ads) regulates actin cytoskeleton in osteoclasts.

  3. Ads (show AGPS Proteins) is a RANKL (show TNFSF11 Proteins) induced early regulator of osteoclastogenesis with a potential role in pre-osteoclast differentiation and fusion.

  4. adseverin induction is a specific gene regulatory effect by TCDD on thymocytes.

  5. Overexpression of Scin is associated with asthma.

Scinderin (SCIN) Protein Profile

Protein Summary

SCIN is a Ca(2+)-dependent actin-severing and -capping protein (Zunino et al., 2001

Gene names and symbols associated with Scinderin Proteins (SCIN)

  • scinderin (scin)
  • scinderin (SCIN)
  • scinderin (LOC100225491)
  • scinderin (Scin)
  • adseverin protein
  • AW545522 protein
  • MGC81993 protein
  • Scind protein
  • si:ch211-134n17.3 protein

Protein level used designations for Scinderin Proteins (SCIN)

scinderin , adseverin , adseverin-like , gelsolin-like protein , SC

444518 Xenopus laevis
472296 Pan troglodytes
475245 Canis lupus familiaris
566764 Danio rerio
693551 Macaca mulatta
100225491 Taeniopygia guttata
100398485 Callithrix jacchus
100441440 Pongo abelii
100496020 Xenopus (Silurana) tropicalis
100592569 Nomascus leucogenys
85477 Homo sapiens
20259 Mus musculus
298975 Rattus norvegicus
281478 Bos taurus
420588 Gallus gallus
100512981 Sus scrofa
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