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Secreted phosphoprotein 1 (SPP1) ELISA Kits

The protein encoded by SPP1 is involved in the attachment of osteoclasts to the mineralized bone matrix. Additionally we are shipping Osteopontin Antibodies (428) and Osteopontin Proteins (58) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SPP1 6696 P10451
SPP1 20750 P10923
SPP1 25353 P08721
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Top Osteopontin ELISA Kits at

Showing 10 out of 118 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.195 ng/mL 0.78-50 ng/mL 96 Tests Log in to see 9 to 11 Days
Rat 7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Log in to see 9 to 11 Days
Dog 0.134 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
Mouse 16 pg/mL 39-2500 pg/mL 96 Tests Log in to see 9 to 11 Days
Rabbit 19.5 pg/mL 78-5000 pg/mL Typical standard curve 96 Tests Log in to see 9 to 11 Days
Pig 5.86 ng/mL 23.5-1500 ng/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
Cow 0.55 ng/mL 1.56-100 ng/mL 96 Tests Log in to see 9 to 11 Days
Pig 0.28 ng/mL 0.78-50 ng/mL 96 Tests Log in to see 9 to 11 Days
Sheep 3.9 ng/mL 15.6-1000 ng/mL   96 Tests Log in to see 11 to 13 Days
Mouse 80 pg/mL 80-20.000 pg/mL 96 Tests Log in to see 2 to 3 Days

Top referenced Osteopontin ELISA Kits

  1. Human Osteopontin ELISA Kit for Sandwich ELISA - ABIN368347 : Toossi, Sadat Amini, Sadat Amini, Partovi Kia, Enamzade, Kazeminejad, Esmaeily Radvar, Younespour: Assessment of serum levels of osteopontin, selenium and prolactin in patients with psoriasis compared with healthy controls, and their association with psoriasis severity. in Clinical and experimental dermatology 2015 (PubMed)
    Show all 4 references for ABIN368347

  2. Mouse (Murine) Osteopontin ELISA Kit for Sandwich ELISA - ABIN415404 : Minai-Tehrani, Jiang, Kim, Chung, Yu, Kim, Shin, Hong, Lee, Kim, Chang, Park, Kang, Cho, Cho: Suppression of tumor growth in xenograft model mice by small interfering RNA targeting osteopontin delivery using biocompatible poly(amino ester). in International journal of pharmaceutics 2012 (PubMed)
    Show all 4 references for ABIN415404

  3. Rat (Rattus) Osteopontin ELISA Kit for Sandwich ELISA - ABIN367452 : Wei, Wang, Wang, Fang, Zhou, Tan, He, Deng: Combination treatment with whole body vibration and a kidney-tonifying herbal Fufang prevent osteoporosis in ovariectomized rats. in Orthopaedic surgery 2015 (PubMed)
    Show all 2 references for ABIN367452

  4. Dog (Canine) Osteopontin ELISA Kit for Sandwich ELISA - ABIN414180 : Kuraoka, Kimura, Nagata, Okada, Aoki, Tachimori, Yonemoto, Imamura, Takeda: Serum Osteopontin as a Novel Biomarker for Muscle Regeneration in Duchenne Muscular Dystrophy. in The American journal of pathology 2016 (PubMed)

More ELISA Kits for Osteopontin Interaction Partners

Human Secreted phosphoprotein 1 (SPP1) interaction partners

  1. Osteopontin/EGFR (show EGFR ELISA Kits)-dependent mitosis-like condensed chromatin protected cells against radiation-induced DNA double-strand breaks and repressed putative negative regulators of stem-like properties.

  2. Results also show a decrease in serum osteopontin levels in women with associated deep infiltrating endometriosis and focal adenomyosis compared to women with superficial peritoneal endometriosis.

  3. The TALK-1/iOPN complex caused Vm hyperpolarization and reduced beta-cell glucose-stimulated Ca2 (show CA2 ELISA Kits)+ influx, which is predicted to inhibit glucose stimulated insulin (show INS ELISA Kits) secretion.

  4. Data show that increased osteopontin levels are independently associated with type 1 diabetes mellitus (T1DM) pediatric patients.

  5. High circulating levels of SSP1 (show SENP6 ELISA Kits) is associated with melanoma.

  6. High SPP1 expression is associated with malignant pleural mesothelioma.

  7. Studies indicate it was unable to detect any osteopontin (OPN) protein in the 3 pancreatic ductal adenocarcinoma (PDA) cell lines studied and neither the quantity nor the intensity of OPN staining correlated with any of the pathologic variables available to us in the PDA tissue microarray analysis.

  8. In conclusion, plasma level of OPN may act as diagnostic adjuvant biomarkers for community-acquired pneumonia (CAP) and further play a role in clinical assessment of the severity of CAP, which could potentially guide the development of treatment strategies.

  9. In patients with proliferative plasma cell disorders, a correlation was determined between VEGF (show VEGFA ELISA Kits) and interstitial OPN with angiogenic parameters in the monoclonal gammopathy of undetermined significance stage of the disease. In advanced stages, there was a negative correlation between OPN and interstitial OPN with parameters of angiogenesis. Overall survival was significantly shorter for patients with negative OPN.

  10. SPP1 expression is upregulated in human masticatory mucosa during wound healing

Pig (Porcine) Secreted phosphoprotein 1 (SPP1) interaction partners

  1. These data suggested that methylation in the OPN promoter plays a crucial role in the regulation of OPN expression that we found in cloned pigs genome.

  2. The striking breed differences between hyperprolific Large White and Meishanin pigs of secreted phospoprotein 1 expression in endometrium suggest that SPP1 may be associated with placental efficiency.

  3. Microglia incubated in vitro with different concentrations (0.1 fM-1 nM) of recombinant osteopontin showed increased proliferation at 10 fM.

  4. results of this study reveal faster growth rate and differences in pig productivity according to genotypes of the SPP1 gene

  5. Osteopontin could play an important role in the development of neointimal hyperplasia in venous conduits after coronary artery bypass grafting.

  6. A different MSSCP pattern was shown in osteopontin which indicates that mutation is located in promotor region; the A --> G transitions was identified in two positions -617 and -608

  7. The 3' terminal end of the first intron of porcine SPP1 harbors a C/EBPbeta (show CEBPB ELISA Kits) binding site and this binding site is negatively affected by the mutant G allele.

  8. in pregnant pigs SPP1 is induced by conceptus estrogen in uterine luminal epithelium and is regulated in a manner coincident with placental progesterone production

  9. osteopontin promotes pathologic mineralization via calcium pyrophosphate dihydrate crystal formation in articular cartilage.

  10. Osteopontin is detected in the majority of germ cells and is involved in spermatogenesis in boar testis.

Mouse (Murine) Secreted phosphoprotein 1 (SPP1) interaction partners

  1. OPN induces oxidative stress via the involvement of mitochondria and NOX-4 (show NOX4 ELISA Kits). It may affect mitochondrial morphology and integrity, at least in part, via the involvement of BIK (show BIK ELISA Kits).

  2. Endogenous osteopontin plays a critical role in the prevention of phosphate-induced nephrocalcinosis and vascular calcification in response to high phosphate load.

  3. GATA4 (show GATA4 ELISA Kits) acts as a negative regulator of Bsp (show KLK6 ELISA Kits) expression in osteoblasts.

  4. Genetic deletion of osteopontin in TRAMP (show DPT ELISA Kits) mice skews prostate carcinogenesis from adenocarcinoma to aggressive human-like neuroendocrine cancers.

  5. IFN-gamma (show IFNG ELISA Kits) regulates hypertensive vascular collagen remodeling induced by ANG II (show AGT ELISA Kits) and inhibits the differentiation of Th17 cells by suppressing OPN expression and regulating secretion of inflammatory cytokines.

  6. results indicate that autocrine OPN plays a crucial role in HPC expansion, migration, and subsequent oncogenic transformation of HPCs, which may provide a new insight into hepatocarcinogenesis

  7. OPN produced by hematogenous macrophages induces astrocyte process extension toward the infarct border zone, which may contribute to repair of the ischemic neurovascular unit following stroke

  8. During the priming phase of liver regeneration, osteopontin enhances the recruitment of macrophages and neutrophils, and triggers hepatocyte proliferation through Kupffer cell-derived IL-6 (show IL6 ELISA Kits) release and the downstream activation of Stat3 (show STAT3 ELISA Kits).

  9. OPN deficiency accelerated the spontaneous development of colitis in mice with disrupted gut (show GUSB ELISA Kits) microbiota and macrophage phagocytic activity.

  10. mechanical stretch (MS) directly increased OPN protein expression and secretion in vascular smooth muscle cells.

Cow (Bovine) Secreted phosphoprotein 1 (SPP1) interaction partners

  1. This implies that a majority of the acidic residues within OPN must be engaged in calcium interaction under physiological conditions.

  2. Genetic variations in the SPP1 promoter affect gene expression and the level of osteopontin secretion into bovine milk.

  3. Osteopontin, osteocalcin and OB-cadherin expression in Synthetic nanohydroxyapatite vs bovine hydroxyapatite cultured Osteoblastic-like cells.

  4. osteopontin (OPN) can serve as a process-directing agent for the intrafibrillar mineralization of collagen.

  5. Results suggest a mechanism of the interaction of UO2(2+) with bone metabolism and a new role for osteopontin (OPN) as a metal transporter.

  6. Upon induction of luteolysis, SPP1 serves as a signaling molecule to recruit or activate immune cells to facilitate luteal regression and tissue degradation.

  7. OPN strongly reduces the amount of biofilm formed in a well-defined laboratory model of acidogenic dental biofilm.

  8. This study demonstrates that adhesion of isolated neonatal rat osteoclasts in vitro was augmented on bovine milk osteopontin (bmOPN) with post-translational modifications (PTMs) compared to human Escherichia-coli-derived recombinant OPN without PTMs.

  9. topographical distribution of both the in vivo and in vitro phosphorylation sites of bone sialoprotein (show CRISP1 ELISA Kits)

  10. the bovine osteopontin gene has two functionally distinct clusters of haplotypes within the QTL region on chromosome 6

Rabbit Secreted phosphoprotein 1 (SPP1) interaction partners

  1. Infection of urinary tract by Escherichia coli caused higher than normal expression of promoter protein osteopontin and mucosal damage at renal tubular cells.

Osteopontin (SPP1) Antigen Profile

Antigen Summary

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000

Gene names and symbols associated with SPP1

  • secreted phosphoprotein 1 (spp1) antibody
  • secreted phosphoprotein 1 (SPP1) antibody
  • secreted phosphoprotein 1 (Spp1) antibody
  • sphingosine-1-phosphate phosphatase 1 (Sgpp1) antibody
  • sphingosine-1-phosphate phosphatase 1 (SGPP1) antibody
  • 2AR antibody
  • AI463453 antibody
  • Apl-1 antibody
  • BNSP antibody
  • Bsp antibody
  • BSPI antibody
  • Eta antibody
  • ETA-1 antibody
  • OP antibody
  • Opn antibody
  • Opnl antibody
  • OSP antibody
  • Ric antibody
  • SPP antibody
  • Spp-1 antibody
  • SPP1 antibody
  • SPPase1 antibody
  • Spph1 antibody
  • zgc:111821 antibody

Protein level used designations for SPP1

spp1 protein , osteopontin , SPP1/CALPHA1 fusion , early T-lymphocyte activation 1 , nephropontin , osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein , secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1) , urinary stone protein , uropontin , SPP-1 , bone sialoprotein 1 , 44 kDa bone phosphoprotein , calcium oxalate crystal growth inhibitor protein , early T-lymphocyte activation 1 protein , minopontin , osteopontin-like protein , Sialoprotein (osteopontin) , bone sialoprotein I , osteopontin-K , OC-1 , secreted phosphoprotein-1 , SPPase1 , sphingosine-1-phosphatase 1 , hSPP1 , hSPPase1 , spp1

432385 Danio rerio
6696 Homo sapiens
478471 Canis lupus familiaris
397087 Sus scrofa
20750 Mus musculus
25353 Rattus norvegicus
281499 Bos taurus
100008982 Oryctolagus cuniculus
395210 Gallus gallus
443058 Ovis aries
100860805 Capra hircus
81535 Mus musculus
81537 Homo sapiens
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