anti-Selenoprotein P (SEPP1) Antibodies

SEPP1 encodes a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. Additionally we are shipping Selenoprotein P Kits (22) and Selenoprotein P Proteins (17) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SEPP1 6414 P49908
SEPP1 20363 P70274
SEPP1 29360 P25236
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Top anti-Selenoprotein P Antibodies at

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Horse Rabbit Un-conjugated WB WB Suggested Anti-SEPP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB SEPP1 Antibody (Center)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the SEPP1 antibody detected the SEPP1 protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Jurkat B: Raji 10% SDS PAGE antibody diluted at 1:1000 IHC-P Image Selenoprotein P antibody detects Selenoprotein P protein at cytoplasm in human colon by immunohistochemical analysis. Sample: Paraffin-embedded human colon. Selenoprotein P antibody , diluted at 1:1000. 100 μL Log in to see 1 to 2 Days
Human Mouse Un-conjugated ELISA, WB 100 μL Log in to see 7 to 9 Days
Human Rabbit Un-conjugated WB SEPP1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: SeP Antibody [NBP1-80766] - Staining of human prostate shows strong cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10 to 13 Days
Human Rabbit Un-conjugated IHC (p), ELISA, WB   50 μg Log in to see 12 to 14 Days
Human Rabbit Biotin ELISA, WB   100 μg Log in to see 7 to 9 Days
Human Rabbit FITC ELISA, WB   100 μg Log in to see 7 to 9 Days

SEPP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine) ,

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Rat (Rattus)

Top referenced anti-Selenoprotein P Antibodies

  1. Horse (Equine) Polyclonal SEPP1 Primary Antibody for WB - ABIN2774140 : Peters, Chatterjee, Hayes, Schoen, Wang, Chanock, Foster: Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008 (PubMed)

More Antibodies against Selenoprotein P Interaction Partners

Human Selenoprotein P (SEPP1) interaction partners

  1. Inc (show PLXNB1 Antibodies)reased amounts of circulating SeP predicted the ineffectiveness of training on endurance capacity in humans.

  2. Results indicate that the 2 genetic variants of rs7579 and rs230813 in SEPP1 may not play a role in the pathogenesis of preeclampsia in Chinese Han Women.

  3. erum microRNA-7 and selenoprotein P appear to be potential non-invasive diagnostic markers for hepatocellular carcinoma. Moreover, the results suggest that selenium could be used as an anticancer therapy for hepatocellular carcinoma by affecting both microRNA-7 and selenoprotein P

  4. The selenium levels in the tissues were correlated to the genotype of the SELENOP selenium carrier protein, but not to other proteins whose levels have been reported to be responsive to selenium availability, including GPX1 (show GPX1 Antibodies), SELENOF and SBP1 (show MEGF8 Antibodies).

  5. GPX1 (show GPX1 Antibodies) and SEPP1 Single Nucleotide Polymorphism were not associated with any changes in the expression of related genes. GPX1 (show GPX1 Antibodies) was shown to modulate the expression of unrelated target, SEP15 (show SEP15 Antibodies), upon Se supplementation, both alone and in combination with SEPP1.

  6. Data show that the cell proliferative ability was inhibited in the cells overexpressing selenoprotein P, plasma 1 (SEPP1), and the colony forming ability of The cell evidently decreased.

  7. Selenoprotein P concentrations are not elevated in women with gestational diabetes mellitus but are associated with BMI and HDL (show HSD11B1 Antibodies) cholesterol.

  8. Studied gene-specific regulation of hepatic selenoprotein expression by interleukin-6 (show IL6 Antibodies); by testing human hepatocytes in culture, found IL-6 (show IL6 Antibodies) reduced the concentrations of SePP mRNA and secreted SePP in a dose-dependent manner.

  9. women who carry the SEPP1 rs3877899 A allele are better able to maintain selenium status during pregnancy, and their GPx3 (show GPX3 Antibodies) activity increases more with supplementation, which suggests better protection from low selenium status.

  10. this study provide preliminary genetic evidence that the SEPP1 functional variants contribute to the AAA (show APP Antibodies) risk.

Mouse (Murine) Selenoprotein P (SEPP1) interaction partners

  1. SeP (show EPHX2 Antibodies) causes exercise resistance through its muscle receptor low-density lipoprotein receptor-related protein 1 (LRP1 (show LRP1 Antibodies)). SeP (show EPHX2 Antibodies)-deficient mice showed a 'super-endurance' phenotype after exercise training, as well as enhanced reactive oxygen species production, AMPK (show PRKAA1 Antibodies) phosphorylation and Ppargc-1alpha expression in skeletal muscle.

  2. Through correlational analysis, it was determined that the effects of Se-supplement were closely related to SelP expression, inflammatory cytokines, and apoptosis molecule production.

  3. This study showed that Male mice lacking two key genes involved in Se metabolism (Scly (show SCLY Antibodies)(-/-)Sepp1(-/-) mice), selenoprotein P (Sepp1) and Sec lyase (Scly (show SCLY Antibodies)), develop severe neurological dysfunction, neurodegeneration, and audiogenic seizures.

  4. Results indicate that selenoprotein P (Sepp1) is important for this transport in selenium-replete mice but that glutathione peroxidase-3 (Gpx3 (show GPX3 Antibodies)) is not.

  5. Sepp1 haploinsufficiency or mutations that disrupt either the selenium transport or the enzymatic domain of SEPP1 exhibit increased colitis-associated carcinogenesis via increased genomic instability and promotion of a protumorigenic microenvironment

  6. plasma Sepp1(UF) and small selenium-containing proteins are filtered by the glomerulus and taken up by PCT (show UROD Antibodies) cells via megalin (show LRP2 Antibodies)-mediated endocytosis.

  7. Tandem Sepp1-apoER2 (show LRP8 Antibodies) interactions supply selenium for maintenance of brain neurons both at the blood-brain barrier and within the brain. Sepp1 inside the blood-brain barrier is taken up by neurons via apoER2 (show LRP8 Antibodies), concentrating brain selenium in them.

  8. These findings provide the first in vivo evidence that Scly (show SCLY Antibodies) and Sepp1 work cooperatively to maintain selenoprotein function in the mammalian brain.

  9. longer isoforms of Sepp1 with high selenium content interact with a binding site distinct from the ligand-binding domain of apoER2 (show LRP8 Antibodies) for selenium delivery

  10. metformin decreases binding of FoxO3a (show FOXO3 Antibodies), a direct target of AMPK (show PRKAA1 Antibodies), to the SEPP1 promoter.

Selenoprotein P (SEPP1) Antigen Profile

Protein Summary

This gene encodes a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is an extracellular glycoprotein, and is unusual in that it contains 10 Sec residues per polypeptide. It is a heparin-binding protein that appears to be associated with endothelial cells, and has been implicated to function as an antioxidant in the extracellular space. Several transcript variants, encoding either the same or different isoform, have been found for this gene.

Gene names and symbols associated with anti-Selenoprotein P (SEPP1) Antibodies

  • selenoprotein P, plasma, 1 (SEPP1) antibody
  • selenoprotein P, plasma, 1 (sepp1) antibody
  • selenoprotein P (SEPP1) antibody
  • selenoprotein P (SeP) antibody
  • selenoprotein P, plasma, 1 (Sepp1) antibody
  • AU018766 antibody
  • D15Ucla1 antibody
  • DKFZp459B039 antibody
  • MGC88974 antibody
  • Se-P antibody
  • selp antibody
  • SeP antibody
  • SEPP1 antibody

Protein level used designations for anti-Selenoprotein P (SEPP1) Antibodies

selenoprotein P , plasma selenoprotein P , seP , selenoprotein P-like protein

431587 Gallus gallus
448755 Xenopus (Silurana) tropicalis
461897 Pan troglodytes
479346 Canis lupus familiaris
698917 Macaca mulatta
100037964 Sus scrofa
100052968 Equus caballus
100174535 Pongo abelii
100329002 Saccoglossus kowalevskii
6414 Homo sapiens
20363 Mus musculus
282066 Bos taurus
29360 Rattus norvegicus
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