Semenogelin II Proteins (SEMG2)

The secreted protein encoded by SEMG2 is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Additionally we are shipping SEMG2 Antibodies (32) and SEMG2 Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse SEMG2 SEMG2 64335  
SEMG2 6407 Q02383
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Top SEMG2 Proteins at

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see 10 to 12 Days

SEMG2 Proteins by Origin and Source

Origin Expressed in Conjugate

More Proteins for Semenogelin II (SEMG2) Interaction Partners

Mouse (Murine) Semenogelin II (SEMG2) interaction partners

  1. Report the gene duplication of SVS III in both mouse and rat.

Human Semenogelin II (SEMG2) interaction partners

  1. Peptides released by physiological cleavage of Semg1 (show SEMG1 Proteins) and Semg2 form amyloids that enhance HIV infection.

  2. SgII transcripts were demonstrated in several tissues, with the strongest signals coming from seminal vesicles, vas (show AVP Proteins) deferens, prostate, epididymis and trachea.

  3. structural changes in the semenogelin 1 (show SEMG1 Proteins) and 2 proteins that have arisen since the human-chimpanzee-gorilla split may be responsible for the physiological differences between these species ejaculated semen that correlate with their sociosexual behavior

  4. The binding of Zn2+ to SgI and SgII and their involvment in regulating the activity of PSA are reported.

  5. SGII is a novel target for protein S-nitrosylation in spermatozoa.

  6. semenogelins I and II were directly cleaved by KLK14 (show KLK14 Proteins). Semenogelins were also able to reverse KLK14 (show KLK14 Proteins) inhibition by Zn2+, providing a novel regulatory mechanism for KLK14 (show KLK14 Proteins) activity.

  7. Semenogelins (Sgs (show FBN1 Proteins)) modifies the membrane structure, indirectly inhibiting motility, and provides suggestions for a therapy for male infertility through selection of a functional sperm population using Sgs (show FBN1 Proteins).

SEMG2 Protein Profile

Protein Summary

The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20.

Gene names and symbols associated with Semenogelin II Proteins (SEMG2)

  • seminal vesicle secretory protein 3A (Svs3a)
  • semenogelin II (SEMG2)
  • 9530026M05Rik protein
  • BB121242 protein
  • Semg2 protein
  • SGII protein
  • Svp-3 protein
  • Svp3 protein
  • Svs3 protein

Protein level used designations for Semenogelin II Proteins (SEMG2)

SVS III , semenogelin II , seminal vesicle protein 3 , seminal vesicle secretion 3 , seminal vesicle secretion 3 alpha , seminal vesicle secretion 3A , semenogelin-2 , SGII , semenogelin 2 , Semenogelin 2

64335 Mus musculus
493189 Pan troglodytes
100137513 Papio anubis
6407 Homo sapiens
100137039 Pongo abelii
711317 Macaca mulatta
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