Serine Racemase Proteins (SRR)

catalyzes the conversion of L-serine to D-serine [RGD, Feb 2006].. Additionally we are shipping Serine Racemase Antibodies (57) and Serine Racemase Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SRR 63826 Q9GZT4
SRR 27364 Q9QZX7
SRR 303306 Q76EQ0
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Top Serine Racemase Proteins at

Showing 10 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HOST_Escherichia coli (E. coli) Human His tag 10 μg Log in to see 15 to 19 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Bioactivity measured with Activity Assay Validation with Western Blot 20 μg Log in to see 20 Days
Yeast Schizosaccharomyces pombe His tag   1 mg Log in to see 60 to 71 Days
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
HOST_Escherichia coli (E. coli) Human His tag   10 μg Log in to see 11 to 12 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 2 to 3 Days

SRR Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Serine Racemase (SRR) Interaction Partners

Human Serine Racemase (SRR) interaction partners

  1. Data suggest that Ser (show SIGLEC1 Proteins)-84 and Arg-135 are important in catalysis and substrate specificity of SRR.

  2. Magnesium and calcium ions differentially affect human serine racemase activity and modulate its quaternary equilibrium toward a tetrameric form

  3. MiR (show MLXIP Proteins)-193a-3p and miR (show MLXIP Proteins)-193a-5p play important roles in osteosarcoma metastasis through down-regulation of the Rab27B (show RAB27B Proteins) and SRR genes and therefore may serve as useful biomarkers for the diagnosis of osteosarcoma

  4. Loss-of-function mutation of the gene encoding serine racemase significantly attenuates excitotoxicity in retina.

  5. Serine racemase activity and dynamics are regulated by halides, ATP and malonate.

  6. In serine racemase, similarly to the related enzyme alanine racemase, the unprotonated pyridoxal-5'-phosphate -substrate intermediate is stabilized mostly due to solvation effects contributed by water molecules and active-site residues.

  7. FBXO22 (show FBXO22 Proteins) protein is required for optimal synthesis of NMDA receptor coagonist D-serine by interacting with serine racemase, activating it, and preventing its targeting to membranes.

  8. S84A serine racemase mutant behaved like serine dehydratase (show SDS Proteins), whereas A65S serine dehydratase (show SDS Proteins) mutant acquired an additional function of using D-serine as a substrate.

  9. Six SNP(rs7754840 in CDKAL1 (show CDKAL1 Proteins), rs391300 in SRR, rs2383208 in CDKN2A/2B, rs4402960 in IGF2BP2 (show IGF2BP2 Proteins), rs10830963 in MTNR1B, rs4607517 in GCK (show GCK Proteins))risk alleles of type 2 diabetes were associated with GDM in pregnant Chinese women.

  10. Serine racemase and D-serine are involved in both pre-symptomatic and progressive phases of amyotrophic lateral sclerosis, demonstrating a link between mutant superoxide dismutase (SOD)1 (show SOD1 Proteins) and a glial-derived toxic mediator in transgenic mice.

Mouse (Murine) Serine Racemase (SRR) interaction partners

  1. results indicate that SRR indeed acts as a d-Asp (show C3 Proteins) biosynthetic enzyme in some organs and/or tissues, and also provide evidences that there should be some additional enzyme for d-Asp (show C3 Proteins) synthesis in mammals.

  2. data show neuronal serine racemase could regulate the extracellular D-serine signaling responsible for N-methyl-D-aspartate type glutamate (show GRIN1 Proteins) receptor activation in the hippocampus

  3. The retinal levels of d-serine are tightly controlled during the first week of postnatal life and vary according to deficiencies in Serine racemase.

  4. In the neocortex and hippocampus only 24-40% of interneurons expressed serine racemase.

  5. SR interacts with the synaptic proteins, postsynaptic density protein 95 (PSD-95 (show DLG4 Proteins)) and stargazin, forming a ternary complex.

  6. The findings of this study suggest that D-serine-dependent NMDAR (show GRIN1 Proteins) activity is involved in mediating the cellular and behavioral effects of 5-HT2AR activation.

  7. serine racemase in the skin epidermis is involved in the differentiation of epidermal keratinocytes and the formation of the skin barrier

  8. Disruption of D-serine synthesis, by blocking SRR, during developmental stages leads to behavioral abnormalities relevant to prodromal symptoms and schizophrenia.

  9. SRR and/or d-serine may be involved in the production of d-aspartic acid in mouse forebrains

  10. The serine racemase-null mutant mouse has less than 10% of normal brain D-serine in a model of schizophrenia

Serine Racemase (SRR) Protein Profile

Protein Summary

catalyzes the conversion of L-serine to D-serine

Gene names and symbols associated with Serine Racemase Proteins (SRR)

  • serine racemase-like (LOC100355322)
  • serine racemase (SRR)
  • serine racemase (srr)
  • serine racemase (NGR_b19540)
  • serine racemase (ZPR_3642)
  • serine racemase (MGYG_07950)
  • Serine racemase (Halhy_2637)
  • Serine racemase (Runsl_3290)
  • serine racemase (Srr)
  • DDBDRAFT_0188432 protein
  • DDBDRAFT_0230209 protein
  • DDB_0188432 protein
  • DDB_0230209 protein
  • ILV1 protein
  • ISO1 protein
  • Srs protein

Protein level used designations for Serine Racemase Proteins (SRR)

serine racemase , Serine racemase , D-serine ammonia-lyase , D-serine dehydratase , L-serine ammonia-lyase , L-serine dehydratase

100355322 Oryctolagus cuniculus
703426 Macaca mulatta
747543 Pan troglodytes
771635 Gallus gallus
4196066 Roseobacter denitrificans OCh 114
7789276 Sinorhizobium fredii NGR234
8627151 Dictyostelium discoideum AX4
9079513 Zunongwangia profunda SM-A87
10025016 Arthroderma gypseum CBS 118893
10586809 Haliscomenobacter hydrossis DSM 1100
10871823 Runella slithyformis DSM 19594
100144980 Xenopus (Silurana) tropicalis
100393154 Callithrix jacchus
100587573 Nomascus leucogenys
63826 Homo sapiens
27364 Mus musculus
303306 Rattus norvegicus
525340 Bos taurus
491200 Canis lupus familiaris
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