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Serotonin Receptor 3B Proteins (HTR3B)

The product of HTR3B belongs to the ligand-gated ion channel receptor superfamily. Additionally we are shipping Serotonin Receptor 3B Antibodies (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse HTR3B HTR3B 57014 Q9JHJ5
HTR3B 9177 O95264
Rat HTR3B HTR3B 58963 Q9JJ16
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Top Serotonin Receptor 3B Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days

HTR3B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,

More Proteins for Serotonin Receptor 3B (HTR3B) Interaction Partners

Mouse (Murine) Serotonin Receptor 3B (HTR3B) interaction partners

  1. Results indicate that vestibular ganglion cells express functional 5-HT3 receptor (show HTR3A Proteins) channels (with 5-HT3a (show HTR3A Proteins) and 5-HT3b subunits) and might play a modulatory role in the peripheral vestibular nervous system

  2. adaptive changes occur in the subunit composition of enteric 5-HT(3 (show HTR3A Proteins)) receptors of 5-HT (show DDC Proteins) transporter -/- mice that are reflected in 5-HT(3 (show HTR3A Proteins)) receptor affinity and desensitization

  3. The 5-HT3B subunit alters the functional properties of 5-HT3 (show HTR3A Proteins) receptors native to neuroblastoma (show ARHGEF16 Proteins) cells.(rat 5-Ht3B)

  4. 5-HT (show DDC Proteins) mediates enhanced neurogenic contractions of the mouse bladder muscle by an action at 5-HT(3 (show HTR3A Proteins)) receptors. The presence of the 5-HT(3 (show HTR3A Proteins)) receptor was confirmed by the expression of both 5-HT (show DDC Proteins)(3A) and 5-HT(3B) receptor subunits.

Human Serotonin Receptor 3B (HTR3B) interaction partners

  1. Study demonstrates that the 5-HT3Br1 transcriptional variant of the 5-HT3B subunit can contribute to the functional properties of heteromeric receptors in a similar manner to the originally characterized 5-HT3B subunit

  2. The response to ondansetron for PONV was significantly influenced by the -100_-102AAG deletion polymorphisms of the 5-HT3B gene. Thus, the -100_-102AAG deletion variants may be a pharmacogenetic predictor for responsiveness to ondansetron for PONV.

  3. HTR3B gene variants may contribute to variability in severity of and response to antiemetic therapy for nausea and vomiting of pregnancy.

  4. we found an association of the HTR3B with poor concentration in schizophrenia patients.These results suggest that the HTR3B may be involved in the attention problem of schizophrenia in Korean population.

  5. Data suggest that HTR3A (show HTR3A Proteins)/HTR3B subunits readily form functionally distinct heteromeric receptors; molecular models have been developed regarding affinities of competitive ligands, non-competitive antagonists, and allosteric modulators. [REVIEW]

  6. This is the first study to show an association between 5-HTR3B and PCS scores, thus suggesting a role of the serotonin pathway in pain catastrophizing.

  7. The ability of 5-HT (show DDC Proteins) to gate the homomeric or heteromeric receptor appears to rely on the D loop triplet RQY of the complementary face.

  8. variants in HTR3A (show HTR3A Proteins), HTR3B, and SLC6A4 (show SLC6A4 Proteins) interactively contribute to etiology of alcohol, cocaine, and nicotine dependence

  9. Genetic interactions between HTR3B, HTR3A (show HTR3A Proteins) and SLC6A4 (show SLC6A4 Proteins) play a significant role in nicotine dependence in both European American and African American smokers.

  10. Five single nucleotide polymorphisms (SNPs) in HTR3A (show HTR3A Proteins) and HTR3B were found.

Serotonin Receptor 3B (HTR3B) Protein Profile

Protein Summary

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor.

Gene names and symbols associated with Serotonin Receptor 3B Proteins (HTR3B)

  • 5-hydroxytryptamine (serotonin) receptor 3B (HTR3B)
  • 5-hydroxytryptamine (serotonin) receptor 3B (Htr3b)
  • 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic (HTR3B)
  • 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic (Htr3b)
  • 5-HT3B protein
  • HTR3B protein

Protein level used designations for Serotonin Receptor 3B Proteins (HTR3B)

5-hydroxytryptamine (serotonin) receptor 3B , 5-hydroxytryptamine receptor 3B-like , 5-HT3 receptor subunit B , 5-HT3-B , 5-hydroxytryptamine receptor 3B , serotonin receptor 3B , 5-hydroxytryptamine 3 receptor B subunit , serotonin-gated ion channel subunit , 5-HT-3B , 5-HT3B

466788 Pan troglodytes
541055 Bos taurus
611236 Canis lupus familiaris
694830 Macaca mulatta
100406499 Callithrix jacchus
100446989 Pongo abelii
100468950 Ailuropoda melanoleuca
100598833 Nomascus leucogenys
100625976 Sus scrofa
57014 Mus musculus
9177 Homo sapiens
58963 Rattus norvegicus
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