anti-Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN) Antibodies

The protein encoded by SNRPN is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. Additionally we are shipping SNRPN Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SNRPN 20646 P63163
SNRPN 6638 P63162
SNRPN 81781 P63164
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Top anti-SNRPN Antibodies at

Showing 10 out of 70 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB SNRPN Antibody (N-term) (ABIN658453) western blot analysis in Hela cell line lysates (35 µg/lane). This demonstrates the SNRPN antibody detected the SNRPN protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated IHC (p), WB Anti- SNRPN Picoband antibody, Western blotting All lanes: Anti SNRPN  at 0.5ug/ml Lane 1: Rat Thymus Tissue Lysate at 50ug Lane 2: HELA Whole Cell Lysate at 40ug Lane 3: HEPG2 Whole Cell Lysate at 40ug Lane 4: HEPA Whole Cell Lysate at 40ug Predicted bind size: 25KD Observed bind size: 32KD Anti- SNRPN Picoband antibody, IHC(P) IHC(P): Rat Thymus Tissue 100 μg Log in to see 4 to 6 Days
Cow Rabbit Un-conjugated WB WB Suggested Anti-SNRPN AntibodyTitration: 1.0 µg/mL  Positive Control: THP-1 Whole Cell 100 μL Log in to see 2 to 3 Days
Human Mouse Un-conjugated ICC, IF, IHC (p), IP, IHC, ELISA, WB 0.1 mL Log in to see 7 to 9 Days
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
Dog Mouse Un-conjugated BI, IHC (f), IF, WB Western blot analysis of SMN on a HepG2 cell lysate (Human hepatocellular carcinoma, ATCC HB-8065) (left). Lane 1: 1:5000, lane 2: 1:10,000, lane 3: 1:20,000 dilution of the mouse anti-SMN antibody. Immunohistochemical staining of pyrimidal cells in a rat cortex, formalin-fixed paraffin-embedded tissue section, with citrate pre-treatment (magnification, 20X) (center). 50 μg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated ICC, IHC (p), WB Anti-SNRPN antibody, Western blotting Lane 1: Rat kidney Tissue Lysate Lane 2: U87 Cell Lysate Lane 3: U87 Cell Lysate Lane 4: HELA Cell Lysate Lane 5: HMY Cell Lysate Lane 6: NEUR Cell Lysate Anti-SNRPN antibody, ICC ICC: HELA Cell 100 μg Log in to see 4 to 6 Days
Human Goat Un-conjugated ELISA, WB Western Blot: SMN1 / SMN2 Antibody [ABIN252925] - ABIN252925 (2µg/ml) staining of Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: SMN Antibody [ABIN2529259] - Analysis of SMN1 in human brain (cerebellum) lysate (35ug protein in RIPA buffer) using this antibody at 0.1 ug/ml. 0.1 mg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: SNRPN Antibody [NBP1-83280] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells); Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells). Western Blot: SNRPN Antibody [NBP1-83280] - Lane 1: Marker [kDa] 220, 112, 84, 47, 32, 26, 17.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp 0.1 mL Log in to see 7 to 9 Days
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 16 Days

SNRPN Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Human ,
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Rat (Rattus) ,
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Top referenced anti-SNRPN Antibodies

  1. Human Monoclonal SNRPN Primary Antibody for ICC, IF - ABIN151435 : Giesemann, Rathke-Hartlieb, Rothkegel, Bartsch, Buchmeier, Jockusch, Jockusch: A role for polyproline motifs in the spinal muscular atrophy protein SMN. Profilins bind to and colocalize with smn in nuclear gems. in The Journal of biological chemistry 2000 (PubMed)
    Show all 19 references for 151435

  2. Dog (Canine) Monoclonal SNRPN Primary Antibody for BI, IHC (f) - ABIN968085 : Cifuentes-Diaz, Frugier, Tiziano, Lacène, Roblot, Joshi, Moreau, Melki: Deletion of murine SMN exon 7 directed to skeletal muscle leads to severe muscular dystrophy. in The Journal of cell biology 2001 (PubMed)
    Show all 5 references for 968085

  3. Cow (Bovine) Polyclonal SNRPN Primary Antibody for WB - ABIN610748 : Buschmann, Lerner, Lee, Ronai: The Mdm-2 amino terminus is required for Mdm2 binding and SUMO-1 conjugation by the E2 SUMO-1 conjugating enzyme Ubc9. in The Journal of biological chemistry 2001 (PubMed)
    Show all 3 references for 610748

  4. Human Polyclonal SNRPN Primary Antibody for ELISA, WB - ABIN252925 : Setola, Terao, Locatelli, Bassanini, Garattini, Battaglia: Axonal-SMN (a-SMN), a protein isoform of the survival motor neuron gene, is specifically involved in axonogenesis. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
    Show all 2 references for 252925

  5. Human Polyclonal SNRPN Primary Antibody for IHC, IHC (p) - ABIN4354968 : Jing, Zhao, Wang, Zhao, Liang, Wang, Ma: Effect of small nuclear ribonucleoprotein-associated polypeptide N on the proliferation of medulloblastoma cells. in Molecular medicine reports 2015 (PubMed)

  6. Human Polyclonal SNRPN Primary Antibody for IHC (p), WB - ABIN658453 : Kuslich, Kobori, Mohapatra, Gregorio-King, Donlon: Prader-Willi syndrome is caused by disruption of the SNRPN gene. in American journal of human genetics 1999 (PubMed)

More Antibodies against SNRPN Interaction Partners

Mouse (Murine) Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN) interaction partners

  1. The androgenetic patterns of H19 (show NCKAP1 Antibodies), Snrpn, and Mest (show MEST Antibodies) were maintained even after differentiation of germline-derived pluripotent stem cells(gPS (show NBEAL2 Antibodies)) into neural stem cells(NSC), whereas the fully unmethylated status of Ndn (show NDN Antibodies) in SSCs was altered to somatic patterns in gPS (show NBEAL2 Antibodies) cells and gPS (show NBEAL2 Antibodies)-NSCs.

  2. These data indicate that oocytes undergo time-dependent demethylation of Snrpn differentially methylated regions during the process of postovulatory aging.

  3. Oocytes vitrification could lead to the loss of DNA methylation (show HELLS Antibodies) of imprinted genes (H19 (show NCKAP1 Antibodies), Peg3 (show PEG3 Antibodies), and Snrpn) in mouse blastocysts, which is mainly caused by the reductions of DNMTs after vitrification of oocytes.

  4. These results support a model in which transcription from the Snrpn upstream exons directs the maternal imprint at the PWS-IC

  5. Snrpn gene is imprinted, with monoallelic expression from the paternal allele in brain and heart.

  6. the ATG-to-AAG (show C16orf35 Antibodies) mutation causes a 15-fold or more increase in translation of the downstream ORF in two fusion constructs, and it is likely that similar translational control affects the normal Snurf-Snrpn (show SNURF Antibodies) transcript as well

  7. The tissue-specific methylation of the mouse conserved activator sequence and its methylation-sensitive enhancer activity may control expression of imprinting center transcripts, establishing and/or maintaining imprinting in the Snrpn locus.

  8. Mouse model for Prader-Willi syndrome. Deletion of Snrpn gene and putative imprinting-centre is associated with absent expression of the imprinted genes Zfp127, Ndn a (show NDN Antibodies)nd Ipw, and phenotypes similar to those found in Prader-Willi infants.

Human Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN) interaction partners

  1. we have confirmed that SNRPN methylation increases with age, which raises further questions regarding the role of SNRPN expression during the aging process.

  2. the cases with partial loss of methylation in KCNQ1OT1 and SNRPN present clinical features different to those associated with the corresponding imprinting syndromes

  3. Knockdown of SNRPN was demonstrated to significantly inhibit medulloblastoma cell growth and induce G2/M phase arrest in vitro.

  4. indicate that SmN (show STMN1 Antibodies) expression reduces the level of mature U2 snRNP (show LSM2 Antibodies), leading to alternative splicing

  5. The methylation patterns of the promoters of MTHFR (show MTHFR Antibodies) and SNRPN are associated with changes in sperm motility and morphology, which could lead to male infertility.

  6. Human amniotic fluid mesenchymal stem cells contain a unique epigenetic signature during in vitro cell culture. H19 (show NCKAP1 Antibodies) and KCNQ1OT1 possessed a substantial degree of hypermethylation status, and variable DNA methylation (show HELLS Antibodies) patterns of SNRPN was observed.

  7. In the skeletal muscle of neonate pigs, both NECD (show NDN Antibodies) and SNRPN were maternally imprinted, while UBE3A (show ube3a Antibodies) was not imprinted.

  8. genetic association studies using 1,000 white subjects from Midwestern United States: Three copy number variations (CNV) in PWCR (show NDN Antibodies) are associated with body fat mass, with a higher copy number (CN) associated with an increase of in body fat mass.

  9. Variable methylation of the imprinted gene, SNRPN, supports a relationship between intracranial germ cell tumours and neural stem cells.

  10. SNRPN gene is imprinted, with monoallelic expression from the paternal allele in fetal brain and heart, and in adult brain.

Cow (Bovine) Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN) interaction partners

  1. SNRPN methylation profiles previously observed in mouse and human studies are also conserved in cattle

  2. Results suggest that artificial reproductive techniques, such as prolonged in vitro culture and SCNT, lead to abnormal reprogramming of imprinting of SNRPN gene by altering methylation levels at this locus.

SNRPN Antigen Profile

Protein Summary

The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure.

Gene names and symbols associated with SNRPN

  • small nuclear ribonucleoprotein N (Snrpn) antibody
  • small nuclear ribonucleoprotein polypeptide N (SNRPN) antibody
  • small nuclear ribonucleoprotein polypeptide N (Snrpn) antibody
  • 2410045I01Rik antibody
  • FE294 antibody
  • FE 294 antibody
  • FE 294 psi antibody
  • FE294 psi antibody
  • HCERN3 antibody
  • Peg4 antibody
  • PWCR antibody
  • Pwcr1 antibody
  • RT-LI antibody
  • SM-D antibody
  • sm-N antibody
  • SMN antibody
  • SNRNP-N antibody
  • SNURF-SNRPN antibody

Protein level used designations for SNRPN

sm protein D , sm protein N , sm-D , sm-N , small nuclear ribonucleoprotein-associated protein N , snRNP-N , tissue-specific-splicing protein , SM protein N , tissue-specific splicing protein , FE294 gene for snRNP-associated polypeptide N , FE294 psi pseudogene , smN , small nuclear ribonucleoparticle-associated protein (snRNP) mRNA clone Sm51 , small nuclear ribonucleoparticle-associated protein (snRNP) mRNA, clone Sm51 , small nuclear ribonucleoprotein N

20646 Mus musculus
6638 Homo sapiens
81781 Rattus norvegicus
780877 Bos taurus
100174649 Pongo abelii
Selected quality suppliers for anti-SNRPN (SNRPN) Antibodies
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