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Synapsin II Proteins (SYN2)

SYN2 is a member of the synapsin gene family. Additionally we are shipping Synapsin II Antibodies (29) and Synapsin II Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SYN2 6854  
SYN2 20965 Q64332
Rat SYN2 SYN2 29179 Q63537
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Top Synapsin II Proteins at

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Mouse T7 tag,His tag   100 μg Log in to see 11 to 13 Days

SYN2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

More Proteins for Synapsin II (SYN2) Interaction Partners

Human Synapsin II (SYN2) interaction partners

  1. Both GABRA6 (show GABRA6 Proteins) and Synapsin II polymorphisms are important risk factors for the development of idiopathic generalized epilepsy in a South Indian population.

  2. Results identify SYN2 as a novel predisposing gene for autism spectrum disorders (ASD (show ARSD Proteins)) and strengthen the hypothesis that a disturbance of synaptic homeostasis underlies ASD (show ARSD Proteins).

  3. Synapsin II is involved in the molecular pathway of lithium treatment in bipolar disorder

  4. SYN2 rs3773364 A>G polymorphism is not a risk factor for susceptibility to epilepsy in this case-control study and meta-analysis.

  5. Results from our study indicate the involvement of SYN2 gene polymorphism in conferring risk to epilepsy; however, the genetic variant does not seem to modulate drug-response in epilepsy pharmacotherapy.

  6. This study suggests a positive association between synapsin II and schizophrenia, implying that synapsin II is involved in the etiology of schizophrenia.

  7. synapsin II variants are associated with susceptibility to schizophrenia.

  8. Syn2 is likely to be involved in the etiology or pathogenesis of schizophrenia.

  9. A case-control study with synapsin II was conducted in 506 bipolar disorder patients and 507 healthy individuals from the Han Chinese population. No association was found in this study.

Mouse (Murine) Synapsin II (SYN2) interaction partners

  1. Pharmacological and knockdown experiments showed that activation of sympathetic neurons by SCFA propionate involves SCFA receptor GPR41 (show FFAR3 Proteins) linking to Gbetagamma-PLCbeta3-ERK1/2-synapsin 2

  2. Deletion of synapsin II, a presynaptic protein contributing to epilepsy predisposition in humans, leads to a loss of tonic inhibition in mouse hippocampal slices due to a dramatic decrease in presynaptic asynchronous GABA release.

  3. In synapsin II(-) hippocampal neurons an overexcitable phenotype was observed.

  4. This study demonstrated a seizure-inducing potential of regular handling in both Syn1KO and Syn2KO mice during a period between P21 and 4 1/2 months of age.

  5. Behavioral and neurophysiological features of Syn-2 (show STX2 Proteins) knockout mice are characterized by observation of the development and progress of seizures from postnatal day 20 to 180.

  6. The histone modification marks were significantly increased in bipolar disorder and major depression and this effect was correlated with significant increases in syn2 gene expression.

  7. Syn (show SYP Proteins) II promotes gamma-aminobutyric acid asynchronous release in a Ca(2 (show CA2 Proteins)+)-dependent manner.

  8. Analysis of cultured neurons from wild-type and Syn (show SYP Proteins) I,II,III-deficient triple knock-out (TKO (show MRPS12 Proteins)) mice shows that synaptic vesicles are severely dispersed in the absence of Syns.

  9. We conclude that neither synapsin I (show SYN1 Proteins) nor synapsin II are directly involved in the regulation of glucose-stimulated insulin (show INS Proteins) secretion and Ca(2 (show CA2 Proteins))-dependent exocytosis in mouse pancreatic beta-cells.

  10. Synapsin I (show SYN1 Proteins) and II affect distinct excitatory glutamatergic synapses in the hippocampus, synapsin-dependent modulations of synaptic function may use distinct presynaptic response patterns to induce different classes of presynaptic plasticity.[Review]

Synapsin II (SYN2) Protein Profile

Protein Summary

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. The TIMP4 gene is located within an intron of this gene and is transcribed in the opposite direction. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing of this gene results in two transcripts.

Gene names and symbols associated with Synapsin II Proteins (SYN2)

  • synapsin II (syn2-a)
  • synapsin II (SYN2)
  • synapsin IIa (syn2a)
  • synapsin II (syn2)
  • synapsin-2 (EDI_190690)
  • synapsin II (Syn2)
  • 2900074L19Rik protein
  • AI836018 protein
  • AI841723 protein
  • MGC115109 protein
  • syn1 protein
  • SYN2 protein
  • SYNII protein
  • SYNIIa protein
  • SYNIIb protein
  • zgc:92311 protein

Protein level used designations for Synapsin II Proteins (SYN2)

synapsin II , synapsin IIa , synapsin-2 , synapsin2 , synapsin-2-like , synapsin 2

373810 Xenopus laevis
415963 Gallus gallus
436870 Danio rerio
734421 Xenopus laevis
749839 Pan troglodytes
751980 Taeniopygia guttata
100057285 Equus caballus
100484945 Ailuropoda melanoleuca
100541419 Meleagris gallopavo
5878744 Entamoeba dispar SAW760
6854 Homo sapiens
20965 Mus musculus
29179 Rattus norvegicus
484652 Canis lupus familiaris
782758 Bos taurus
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