Synaptopodin Proteins (SYNPO)

Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. Additionally we are shipping Synaptopodin Antibodies (100) and Synaptopodin Kits (31) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SYNPO 11346 Q8N3V7
SYNPO 104027  
Rat SYNPO SYNPO 60324 Q9Z327
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Top Synaptopodin Proteins at

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 15 to 18 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days

SYNPO Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for Synaptopodin (SYNPO) Interaction Partners

Human Synaptopodin (SYNPO) interaction partners

  1. Urine synaptopodin is associated with serum creatinine elevation in the patients with glomerulonephritis including diabetic kidney disease regardless of urine albumin (show ALB Proteins) excretion. We suggest that the urine synaptopodin level can predict glomerular damage independently of the urine albumin (show ALB Proteins) excretion.

  2. SYNPO variants are involved in AMPA (show GRIA3 Proteins) receptor trafficking and neuronal plasticity, which are associated with cognitive impairment and schizophrenia susceptibility.

  3. This study identified and confirmed SYNPO protein changes within the postsynaptic density in schizophrenia

  4. Case Report: immunohistologically detected synaptopodin upregulation in foamy podocytes in Fabry disease due to novel alpha-galactosidase A (show GLA Proteins) mutation.

  5. expression significantly down-regulated in presence of WT1 (show WT1 Proteins) R458Q mutation

  6. Shear stress induced actin binding proteins including SYNPO may play a critical role in endothelial wound healing.

  7. These results suggested that the SA is an important component of the molecular machinery controlling the calcium-dependent accumulation of AMPA (show GRIA3 Proteins)-receptors (AMPA (show GRIA3 Proteins)-R) at excitatory synapses. [review]

  8. The urinary mRNA profiles of synaptopodin, podocalyxin, CD2-AP, alpha-actin4, and podocin were found to increase with the progression of diabetic nephropathy.

  9. Podocyte BK(Ca) channels are regulated by synaptopodin, Rho, and actin microfilaments.

  10. Heterozygous mutations in the promoters of the ACTN4 (show ACTN4 Proteins) and SYNPO genes are found in patients with idiopathic focal segmental glomerulosclerosis.

Mouse (Murine) Synaptopodin (SYNPO) interaction partners

  1. Results link synaptopodin (SP) with ryanodine receptors, in that ryanodine is able to convert short-term potentiation to long-term potentiation under our testing conditions only in ventral hippocampus, and only in the presence of SP in this region of the hippocampus.

  2. miR-206 was up-regulated in Adriamycin nephropathy mice, which led to severe podocyte injury and inhibited the expression of WT1 and synaptopodin. In vitro, over expression of miR-206 induced WT1 and synaptopodin degradation and actin rearrangement, initiating a catastrophic collapse of the entire podocyte-stabilizing system.

  3. WAVE1 (show WASF1 Proteins) phosphorylation in podocytes. Synaptopodin is a well-characterized target of CsA (show HSPA9 Proteins). WAVE1 (show WASF1 Proteins) overexpression and synaptopodin knockdown experiments directly demonstrated that WAVE1 (show WASF1 Proteins) expression is not dependent on synaptopodin expression, and vice versa

  4. Inhibition of STAT3 (show STAT3 Proteins) signaling in podocytes reduced synaptopodin levels in these cells.

  5. synaptopodin has an essential, calcium store-related role in regulating synaptic plasticity in cultured hippocampal neurons

  6. Our results identify synaptopodin as a substrate of PKA in hippocampal neurons and point to an essential role for synaptopodin in activity-dependent regulation of dendritic spine dynamics and synaptic plasticity in postnatal brain development.

  7. Synaptopodin has an important role in homeostatic synaptic plasticity

  8. Together, these results indicate that alpha-actinin (show ACTN1 Proteins) and the actin cytoskeleton are important components of the cisternal organelle that are probably required to stabilize the AIS (show AR Proteins).

  9. Synpatopodin may play an important role in the changes of PSD-95 and NR1 protein levels and other synaptic alterations that are induced by corticosterone

  10. HGF (show HGF Proteins) protects podocytes from a loss of nephrin (show NPHS1 Proteins), at least in part, through maintaining synaptopodin in nephritic mice with albuminuria.

Synaptopodin (SYNPO) Protein Profile

Protein Summary

Synaptopodin is an actin-associated protein that may play a role in actin-based cell shape and motility. The name synaptopodin derives from the protein's associations with postsynaptic densities and dendritic spines and with renal podocytes (Mundel et al., 1997

Gene names and symbols associated with Synaptopodin Proteins (SYNPO)

  • synaptopodin (SYNPO)
  • synaptopodin (Synpo)
  • synaptopodin-like (LOC100624154)
  • 9030217H17Rik protein
  • 9130229N11 protein
  • 9330140I15Rik protein
  • AW046661 protein
  • DKFZp459N012 protein
  • SYNPO protein

Protein level used designations for Synaptopodin Proteins (SYNPO)

synaptopodin , synaptopodin-like

471697 Pan troglodytes
100029044 Monodelphis domestica
100147046 Equus caballus
100174064 Pongo abelii
100408223 Callithrix jacchus
100470428 Ailuropoda melanoleuca
11346 Homo sapiens
533531 Bos taurus
104027 Mus musculus
60324 Rattus norvegicus
100728174 Cavia porcellus
100344553 Oryctolagus cuniculus
479327 Canis lupus familiaris
770421 Gallus gallus
101110761 Ovis aries
100624154 Sus scrofa
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