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Synaptotagmin VII Proteins (SYT7)

SYT7 is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Additionally we are shipping Synaptotagmin VII Antibodies (74) and Synaptotagmin VII Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SYT7 9066 O43581
SYT7 54525 Q9R0N7
Rat SYT7 SYT7 59267  
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Top Synaptotagmin VII Proteins at

Showing 3 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days

SYT7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
, ,
Mouse (Murine)

More Proteins for Synaptotagmin VII (SYT7) Interaction Partners

Human Synaptotagmin VII (SYT7) interaction partners

  1. Data indicate that small protein sequence changes in the Ca(2 (show CA2 Proteins)+)-binding loops of the C2 domains may give rise to the difference in binding kinetics between Syt-1 (show SYT1 Proteins) and Syt-7 isoforms.

  2. the results suggest that the two C2 domains of Syt7 bind independently to planar membranes, in contrast to reported interdomain cooperativity in Syt1 (show SYT1 Proteins)

  3. The membrane dissociation of SYT7 C2A domain but not SYT1 C2A domain is slowed by Na(2)SO(4) and trehalose, solutes that enhance the hydrophobic effect.

  4. identified the conserved alternative splicing events in the spacer domain of Syt VII; also shown that Syt (show SS18 Proteins) VIIa-GFP is mainly localized in the perinuclear region and tips of neurites (dense-core vesicles), and not in the plasma membrane

Mouse (Murine) Synaptotagmin VII (SYT7) interaction partners

  1. Data (including data from studies in knockout mice) suggest that loss of both Syt1 (show SYT1 Proteins)/Syt7 decreases capacity of readily-releasable pool (RRP (show RRBP1 Proteins)) of Ca2 (show CA2 Proteins)+ in synaptic vesicles without altering rate of priming into RRP (show RRBP1 Proteins); Syt1 (show SYT1 Proteins)/Syt7 functions appear redundant.

  2. synaptotagmin 7 (Syt7) is a calcium sensor that is required for facilitation at several central synapses

  3. Use of neurons from double-knock-out (SNAP-25 (show SNAP25 Proteins), synaptotagmin-7) mice in combination with viral transduction showed that SNAP-23 (show SNAP23 Proteins)-driven release is triggered by endogenous synaptotagmin-7

  4. Complex of syt 7 and calmodulin (show Calm2 Proteins) serves as a key regulator of synaptic vesicle replenishment in presynaptic nerve terminals.

  5. synaptotagmin-7 is directly activated by GLP-1 (show GCG Proteins) signaling and may serve as a drug target for boosting insulin (show INS Proteins) secretion.

  6. knock-out of synaptotagmin-7 selectively impaired delayed asynchronous neurotransmitter release but not synchronous release. In contrast, the readily releasable vesicles after depletion recover normally in knock-out mice.

  7. Ca(2 (show CA2 Proteins)+)-triggered release at a synapse is due to synaptotagmins, with synaptotagmin-7 mediating a slower form of Ca(2 (show CA2 Proteins)+)-triggered release that is normally occluded by faster synaptotagmin-1 (show SYT1 Proteins)-induced release but becomes manifest upon synaptotagmin-1 (show SYT1 Proteins) deletion

  8. Results demonstrate that synaptotagmin-7 functions as a positive regulator of GLP-1 (show GCG Proteins) secretion in intestinal L-cells and GLUTag cells, consistent with its proposed role as a calcium sensor in GLP-1 (show GCG Proteins) secretion.

  9. Somatodendritic dopamine release requires synaptotagmin 4 (show SYT4 Proteins) and 7 and the participation of voltage-gated calcium channels.

  10. In synaptotagmin-7 KO mice defective insulin (show INS Proteins) secretion and reduced insulin (show INS Proteins) sensitivity were not sufficient to cause hyperglycaemia in the absence of enhanced glucagon (show GCG Proteins) secretion

Synaptotagmin VII (SYT7) Protein Profile

Protein Summary

This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with Synaptotagmin VII Proteins (SYT7)

  • CG2381 gene product from transcript CG2381-RB (Syt7)
  • synaptotagmin VII (SYT7)
  • synaptotagmin 7 (syt7)
  • synaptotagmin VII (LOC100342916)
  • synaptotagmin VII (Syt7)
  • AI851541 protein
  • B230112P13Rik protein
  • CG2381 protein
  • CG10322 protein
  • Dmel\\CG2381 protein
  • dsyt7 protein
  • IPCA-7 protein
  • IPCA7 protein
  • MGC145945 protein
  • PCANAP7 protein
  • SYT-VII protein
  • syt7 protein
  • Syt 7 protein
  • SYTVII protein
  • Syt VII protein

Protein level used designations for Synaptotagmin VII Proteins (SYT7)

CG2381-PA , CG2381-PB , CG2381-PF , CG2381-PI , CG2381-PL , Syt7-PA , Syt7-PB , Syt7-PF , Syt7-PI , Syt7-PL , synaptotagmin VII , synaptotagmin 7 , prostate cancer-associated protein 7 , synaptotagmin-7 , sytVII

43783 Drosophila melanogaster
426016 Gallus gallus
780295 Xenopus (Silurana) tropicalis
100062526 Equus caballus
100342916 Oryctolagus cuniculus
100550490 Meleagris gallopavo
9066 Homo sapiens
54525 Mus musculus
59267 Rattus norvegicus
483796 Canis lupus familiaris
540850 Bos taurus
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