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Syntaxin Binding Protein 1 (STXBP1) ELISA Kits

STXBP1 encodes a syntaxin-binding protein. Additionally we are shipping Syntaxin Binding Protein 1 Antibodies (121) and Syntaxin Binding Protein 1 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat STXBP1 STXBP1 25558 P61765
Anti-Human STXBP1 STXBP1 6812 P61764
Anti-Mouse STXBP1 STXBP1 20910 O08599
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More ELISA Kits for Syntaxin Binding Protein 1 Interaction Partners

Human Syntaxin Binding Protein 1 (STXBP1) interaction partners

  1. We conducted a cohort study to analyze STXBP1 in 42 patients with epileptic encephalopathy. We identified four novel mutations: two splicing mutations, a frameshift mutation, and a nonsense mutation.

  2. Reduced expression of STXBP1 leads to changes in the expression and localization of syntaxin-1 (show STX1A ELISA Kits) in pluripotent stem cells from epileptic encephalopathy patient.

  3. Seizure severity and intellectual disability were connected to STXBP1 encephalopathy patients.

  4. partial STXBP1 loss of function robustly impairs neurotransmitter release in human neurons, and suggest that heterozygous STXBP1 mutations cause early epileptic encephalopathy specifically through a presynaptic impairment.

  5. The case described suggests a relationship between the Rett syndrome and the STXBP1 gene not described so far, making the search for STXBP1 gene mutations advisable in patients with Rett syndrome and early onset of epilepsy.

  6. A de novo mutation in STXBP1 was detected with exome sequencing together with profound impairment of complex I of the mitochondrial respiratory chain on muscle biopsy. Findings implicate a secondary impairment of mitochondrial function.

  7. Epileptic encephalopathy related to mutations in the STXBP1 genes.

  8. In vitro interaction assays indicated that Doc2b (show DOC2B ELISA Kits) is required to bridge the interaction between Munc18c and Munc18-1 in the macromolecular complex; Munc18c and Munc18-1 failed to associate in the absence of Doc2b (show DOC2B ELISA Kits)

  9. STXBP1 gene mutation was found in 1 out of 11 patients

  10. STXBP1 mutations associated with early epileptic encephalopathies.

Mouse (Murine) Syntaxin Binding Protein 1 (STXBP1) interaction partners

  1. In this studying the Munc18-1-/- nervous system, we demonstrate that synaptic activity is dispensable for the early formation of spinal motor circuits at the levels of axon guidance, differentiation of transcriptional identity, and mRNA expression.

  2. Vamp2 (show VAMP2 ELISA Kits) mutations that impair Munc18-1 binding inhibit spontaneous as well as evoked neurotransmitter release, providing evidence for the Vamp2 (show VAMP2 ELISA Kits)-regulating function of Munc18-1 in synaptic exocytosis.

  3. A dynamic PKC (show PKC ELISA Kits) phosphorylation/de-phosphorylation cycle of Munc18-1 drives short-term enhancement of transmitter release during post-tetanic potentiation.

  4. miR (show MLXIP ELISA Kits)-218 and miR (show MLXIP ELISA Kits)-322 directly interact with Stxbp1 by targeting the 3'UTR (show UTS2R ELISA Kits) of its mRNA.

  5. Munc18-1 levels correlate with synaptic strength.

  6. Syntaxin binding protein 1 is not required for allergic inflammation via IgE-mediated mast cell activation.

  7. [review] Regulation of cortical F-actin is a shared function of Sec1/Munc18-like proteins; a way to gain more insight in the molecular mechanism underlying the Munc18-1-mediated cortical F-actin regulation is proposed.

  8. The N-terminal syntaxin-1 (show STX1A ELISA Kits) domains mediate different functions in synaptic vesicle fusion, probably via formation of distinct Munc18/SNARE (show VTI1B ELISA Kits)-protein complexes.

  9. SNAREpin assembly by Munc18-1 requires previous vesicle docking by synaptotagmin 1 (show SYT1 ELISA Kits).

  10. a novel indirect role for Munc18-1 in facilitating syntaxin 4 (show STX4 ELISA Kits)-mediated granule pre-docking to support first-phase insulin (show INS ELISA Kits) exocytosis.

Zebrafish Syntaxin Binding Protein 1 (STXBP1) interaction partners

  1. Epilepsy, Behavioral Abnormalities, and Physiological Comorbidities in Syntaxin-Binding Protein 1 (STXBP1) Mutant Zebrafish.

Syntaxin Binding Protein 1 (STXBP1) Antigen Profile

Antigen Summary

This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with STXBP1

  • syntaxin binding protein 1 (stxbp1) antibody
  • syntaxin binding protein 1 (Tb09.160.0780) antibody
  • syntaxin binding protein 1 (STXBP1) antibody
  • syntaxin binding protein 1 (Stxbp1) antibody
  • syntaxin binding protein 1a (stxbp1a) antibody
  • AI317162 antibody
  • AI326233 antibody
  • ANC18HA antibody
  • fj43h10 antibody
  • hunc18 antibody
  • MGC88906 antibody
  • MGC146482 antibody
  • MMS10-G antibody
  • Ms10g antibody
  • Munc-18a antibody
  • MUNC18-1 antibody
  • N-sec1 antibody
  • nsec1 antibody
  • NSEC1A antibody
  • P67 antibody
  • Rb-sec1 antibody
  • RBSEC1 antibody
  • rbSec1A antibody
  • rbSec1B antibody
  • rop antibody
  • Sec1 antibody
  • stxbp1 antibody
  • Sxtbp1 antibody
  • UNC18 antibody
  • Unc18-1 antibody
  • UNC18A antibody
  • Unc18h antibody
  • wu:fj36d12 antibody
  • wu:fj43h10 antibody
  • zgc:114171 antibody

Protein level used designations for STXBP1

syntaxin binding protein 1 , Ras opposite , syntaxin-binding protein 1-like , p67 , protein unc-18 homolog 1 , protein unc-18 homolog A , syntaxin-binding protein 1 , unc-18 homolog , unc-18-1 , unc-18A , N-Sec1 , neuronal SEC1 , unc18-1 , UNC-18 homolog , minisatellite 10g detected by probe MMS10 , syntaxin 1-binding protein

448217 Xenopus (Silurana) tropicalis
779976 Xenopus (Silurana) tropicalis
3660246 Trypanosoma brucei TREU927
100397821 Callithrix jacchus
25558 Rattus norvegicus
6812 Homo sapiens
20910 Mus musculus
404293 Gallus gallus
282378 Bos taurus
100101272 Xenopus laevis
100173563 Pongo abelii
574003 Danio rerio
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