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TBP-Like 1 Proteins (TBPL1)

TBPL1 encodes a member of the TATA box-binding protein family. Additionally we are shipping TBPL1 Antibodies (124) and TBPL1 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TBPL1 237336 P62340
TBPL1 9519 P62380
Rat TBPL1 TBPL1 689030  
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Top TBPL1 Proteins at

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
Yeast Macaca fascicularis His tag   1 mg Log in to see 56 to 66 Days
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Human His-SUMO Tag   50 μg Log in to see 11 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days

TBPL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

Top referenced TBPL1 Proteins

  1. Human TBPL1 Protein expressed in Escherichia coli (E. coli) - ABIN1098505 : Rabenstein, Zhou, Lis, Tjian: TATA box-binding protein (TBP)-related factor 2 (TRF2), a third member of the TBP family. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
    Show all 2 references for ABIN1098505

More Proteins for TBP-Like 1 (TBPL1) Interaction Partners

Mouse (Murine) TBP-Like 1 (TBPL1) interaction partners

  1. Overexpression and knockdown of TLP revealed that the levels of muscle-specific myosin heavy chain and the myogenic transcription factor myogenin are downregulated by TLP. The proximal AT-rich sequence of the myogenin promoter is responsible for TLP-mediated transcriptional repression.

  2. Transplantation of TRF2 (show TERF2 Proteins) overexpressing bone marrow cells into the hematopoietic system of mice resulted in the the development of T-cell lymphomas, but overexpression of the TRF2 (show TERF2 Proteins) transgene was not detectable anymore in the tumors.

  3. transcription factor IIA may regulate the intracellular molecular state and the function of TATA-binding protein-like protein (TLP) through its property of binding to TLP

  4. TBP-related factor 2 (TRF2) has a role in mouse spermatogenesis

  5. reconfirmed cytoplasmic localization of TRF2 (show TERF2 Proteins); genotoxins caused it to migrate to the nucleus; TRF2 (show TERF2 Proteins) may be involved in genotoxin-induced transcriptional regulation

  6. these results demonstrate that TRF2 (show TERF2 Proteins) increased expression is a potent oncogenic event that along with telomerase deficiency accelerates carcinogenesis, coincidental with a derepression of telomere recombination

  7. Data report on the nucleosomal organization of telomeres that have become deprotected through the deletion of the shelterin components TRF2 (show TERF2 Proteins) or POT1a (show POT1 Proteins)/b, and show no evidence of changes or nucleosome eviction near the telomere terminus.

  8. Role of TRF2 (show TERF2 Proteins) mRNA in male germ cells: In transgenic animals deficient in TRF2 (show TERF2 Proteins), spermatid development fails during early spermiogenesis with increased apoptosis and failure to develop testicular spermatozoa. Infertility phenotype in homozygote males.

  9. Mice lacking the TBP-related factor 2 (TRF2) gene, which is highly expressed in the testis, have a severe defect in spermiogenesis. TRF2 (show TERF2 Proteins) expression is shown to be cell type- and stage-specific and play an essential regulatory role in development.

Human TBP-Like 1 (TBPL1) interaction partners

  1. The interaction of TBP (show TBP Proteins)-like protein with TFIIA (show GTF2A1 Proteins) is essential to suppress proteasome-dependent turnover of TBP (show TBP Proteins)-like protein

  2. miR18a exhibits a protective role in colorectal cancer (CRC (show CALR Proteins)) via inhibiting proliferation, invasion and migration of CRC (show CALR Proteins) cells by directly targeting the TBPL1 gene.

  3. results suggest that activation of the p21 (show CDKN1A Proteins) upstream promoter is mediated by interaction between specific regions of TLP and p53 (show TP53 Proteins)

  4. Western blotting and immunohistochemistry both indicated a higher TBPL1 protein expression level in colorectal cancer tissue. siRNA for TBPL1 transfection obviously slowed down the cell proliferation in both SW-620 and HT-29 cells.

  5. TLP mediates p53 (show TP53 Proteins)-governed transcriptional activation of the p21 (show CDKN1A Proteins) upstream promoter.

  6. Data show that during interphase, endogenous or exogenously expressed TRF2 (show TERF2 Proteins) is located almost exclusively in the nucleolus

  7. TLF is a functional regulator of transcription with targets distinct from those of TBP (show TBP Proteins).

  8. the knockdown of the endogenous TLP reduced etoposide-induced apoptosis through repression of TAp63 expression. Taken together, our present study identifies a TLP-TAp63 pathway that is further implicated in stress-induced apoptosis.

TBPL1 Protein Profile

Protein Summary

This gene encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. This gene plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.

Gene names and symbols associated with TBP-Like 1 Proteins (TBPL1)

  • TBP-like 1 (TBPL1)
  • TATA box binding protein-like 1 (tbpl1)
  • TBP-like 1 (LOC100232377)
  • TBP-like 1 (LOC100346981)
  • TBP-like 1 (tbpl1)
  • TATA box binding protein-like 1 (Tbpl1)
  • TBP-like 1 (Tbpl1)
  • 4732475G08 protein
  • AW011832 protein
  • AW491032 protein
  • D18347 protein
  • MGC:8389 protein
  • MGC:9620 protein
  • STD protein
  • STUD protein
  • tlf protein
  • tlp protein
  • trf protein
  • trf2 protein
  • trp protein
  • zgc:92340 protein

Protein level used designations for TBP-Like 1 Proteins (TBPL1)

TATA box binding protein-like 1 , TATA box-binding protein-like protein 1 , TBP-like 1 , tata box-binding protein-like protein 1 , 21 kDa TBP-like protein , TATA box binding protein-like protein , TATA box-binding protein-related factor 2 , TBP-like factor , TBP-like protein 1 , TBP-related factor 2 , TBP-related protein , 21-kDA TBP-like protein , second TBP of unique DNA protein , xlTLF , TATA box-binding protein related factor 2

463010 Pan troglodytes
100101453 Takifugu rubripes
100232377 Taeniopygia guttata
100346981 Oryctolagus cuniculus
100528854 Ictalurus punctatus
237336 Mus musculus
9519 Homo sapiens
403035 Danio rerio
399086 Xenopus laevis
395517 Gallus gallus
476209 Canis lupus familiaris
613818 Bos taurus
689030 Rattus norvegicus
100173239 Pongo abelii
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