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Regulator of the DNA damage response (DDR). Additionally we are shipping TTI2 Antibodies (2) and many more products for this protein.
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The findings emphasises the role of the TTI2 gene in the etiology of intellectual disability.
TTI1 and TTI2 protect cells from spontaneous DNA damage, and are required for the establishment of the intra-S and G2/M checkpoint.
Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.
TELO2-interacting protein 2
, Tel2 interacting protein 2 homolog