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Regulator of the DNA damage response (DDR). Additionally we are shipping TTI2 Proteins (3) and many more products for this protein.
Showing 3 out of 5 products:
Human Polyclonal TTI2 Primary Antibody for IP, WB - ABIN4286617
You, Sobreira, Gable, Jurgens, Grange, Belnap, Siniard, Szelinger, Schrauwen, Richholt, Vallee, Dinulos, Valle, Armanios, Hoover-Fong: A Syndromic Intellectual Disability Disorder Caused by Variants in TELO2, a Gene Encoding a Component of the TTT Complex. in American journal of human genetics 2016
The findings emphasises the role of the TTI2 gene in the etiology of intellectual disability.
TTI1 (show TTI1 Antibodies) and TTI2 protect cells from spontaneous DNA damage, and are required for the establishment of the intra-S and G2/M checkpoint.
Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs.
TELO2-interacting protein 2
, Tel2 interacting protein 2 homolog