anti-Tachykinin, Precursor 1 (TAC1) Antibodies

TAC1 encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. Additionally we are shipping Tachykinin, Precursor 1 Kits (131) and Tachykinin, Precursor 1 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse TAC1 TAC1 21333 P41539
Anti-Human TAC1 TAC1 6863 P20366
Anti-Rat TAC1 TAC1 24806 P06767
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Top anti-Tachykinin, Precursor 1 Antibodies at

Showing 10 out of 198 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC (fro), IF, IHC (p) Staining of paraffin embedded human appendix with rabbit anti Substance P (ABIN114011). 0.5 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat liver labeled with Rabbit Anti-Substance P Polyclonal Antibody (ABIN724400) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded rat brain tissue labeled with Rabbit Anti-Substance P Polyclonal Antibody (ABIN724400) 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
Guinea Pig Mouse Un-conjugated EIA, IHC (fro), IF 0.1 mg Log in to see 6 to 8 Days
Dog Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
Cow Rabbit Un-conjugated WB WB Suggested Anti-TAC1 Antibody Titration: 1.0 ug/ml Positive Control: 721_B Whole Cell 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated FACS, WB TAC1 Antibody (C-term) (ABIN652053) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the TAC1 antibody detected the TAC1 protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 6 Days
Human Guinea Pig Un-conjugated ICC, IHC (fro), IF, IHC Immunocytochemistry/Immunofluorescence: Substance P Antibody [ABIN152529] - Detection of Substance P in rat spinal cord dorsal horn (red fluorescence). DAPI (blue) was used as counter stain. 0.05 mL Log in to see 7 to 9 Days
REACT_Bird Rabbit Un-conjugated IEM, ICC, IF, IHC IHC image of staining in rat spinal cord 0.1 mL Log in to see 2 to 3 Days
Human Mouse Un-conjugated EIA, IF   0.1 mg Log in to see 6 to 8 Days

TAC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Tachykinin, Precursor 1 Antibodies

  1. Bird (Avian) Polyclonal TAC1 Primary Antibody for IEM, ICC - ABIN617879 : Hara, Kobayashi: Glycerol injection to the rat trigeminal nerve: histological and immunohistochemical studies. in Acta neurochirurgica 1993 (PubMed)
    Show all 496 references for 617879

  2. Human Polyclonal TAC1 Primary Antibody for ICC, IHC (fro) - ABIN152529 : Kavut, Kalpaklıoğlu, Atasoy: Contribution of neurogenic and allergic ways to the pathophysiology of nonallergic rhinitis. in International archives of allergy and immunology 2013 (PubMed)
    Show all 7 references for 152529

  3. Human Polyclonal TAC1 Primary Antibody for IF (p), IHC (p) - ABIN724400 : Tu, Li, Peng, Hu, Liu, Kong, Liu, Gao, Xu, Xu, Qiu, Fan, Zhu, Yu, Zheng, Wu, Peng, Song, Wu, Liang: P2X(7) inhibition in stellate ganglia prevents the increased sympathoexcitatory reflex via sensory-sympathetic coupling induced by myocardial ischemic injury. in Brain research bulletin 2013 (PubMed)
    Show all 4 references for 724400

  4. Guinea Pig Monoclonal TAC1 Primary Antibody for EIA, IHC (fro) - ABIN192028 : Marquie: Effects of 780 SE on lipid metabolism in rabbit aorta. in European journal of pharmacology 1977 (PubMed)
    Show all 4 references for 192028

  5. Dog (Canine) Polyclonal TAC1 Primary Antibody for WB - ABIN611196 : Discher, Bishopric, Wu, Peterson, Webster: Hypoxia regulates beta-enolase and pyruvate kinase-M promoters by modulating Sp1/Sp3 binding to a conserved GC element. in The Journal of biological chemistry 1998 (PubMed)
    Show all 3 references for 611196

  6. Chicken Polyclonal TAC1 Primary Antibody for IHC (fro), IF - ABIN114011 : Ho, DePalatis: Substance P immunoreactivity in the median eminence of the North American opossum and domestic fowl. in Brain research 1980 (PubMed)

  7. Human Polyclonal TAC1 Primary Antibody for IHC, ELISA - ABIN1585309 : Zhu, Riau, Barathi, Chew, Beuerman: Expression of neural receptors in mouse meibomian gland. in Cornea 2010 (PubMed)

More Antibodies against Tachykinin, Precursor 1 Interaction Partners

Mouse (Murine) Tachykinin, Precursor 1 (TAC1) interaction partners

  1. Evidence for a role of Tac1 in the control of reproductive function in the male mouse, suggesting a predominant central action that may involve a change in the balance of neural factors that control GnRH expression.

  2. This study showed a new evidence that furthers our understanding for the mechanisms underlying Tac2-dependent cellular pathways in fear learning.

  3. This study demonstrated that Activity of Tachykinin1-Expressing Pet1 (show FEV Antibodies) Raphe Neurons Modulates the Respiratory Chemoreflex.

  4. Data show that estrogen receptor alpha (ERalpha (show ESR1 Antibodies)) in tachykinin 2 protein (Tac2) neurons typically restrains pubertal onset and hypothalamic reproductive drive.

  5. RNA-binding protein Msi1 (show MSI1 Antibodies) competes with miR130a and -206 for interaction with TAC1 mRNA, to stabilize and increase its translation

  6. Results reveal that EM-2, Leu-Enk (show PENK Antibodies) and Dyn (show PDYN Antibodies) A were down-regulated in Tac1-/- spinal cord tissues.

  7. Results provide evidence linking enhanced waking activity and the pro-inflammatory molecule substance P to changes in slow-wave activity associated with sleep-active cortical cells that co-express nNOS (show NOS1 Antibodies) and the NK-1R (show TACR1 Antibodies)

  8. Substance P partly accounts for the increased density of microglia in the substantia nigra through chemotaxic recruitment via a novel NK1R (show TACR1 Antibodies)-NOX2 (show CYBB Antibodies) axis-mediated pathway.

  9. We conclude that a dedicated subset of VMHVL neurons marked by ERalpha (show ESR1 Antibodies), NKX2-1 (show NKX2-1 Antibodies), and Tac1 regulates estrogen-dependent fluctuations in physical activity and constitutes one of several neuroendocrine modules that drive sex-specific responses.

  10. Data demonstrate a role TAC1 in the control energy balance by regulating the levels of adiposity in response to ghrelin (show GHRL Antibodies) administration and to changes in the status of the gonadal function.

Human Tachykinin, Precursor 1 (TAC1) interaction partners

  1. Data suggest that serum substance P concentrations at the day of oocyte retrieval after ovulation induction may be used to predict oocyte maturation during in vitro oocyte maturation to be followed by intracytoplasmic sperm injections and may be an indirect indicator for treatment outcome in women with infertility.

  2. Expression substance P/neurokinin A/hemokinin-1 and their preferred neurokinin 1/neurokinin 2 receptors are dysregulated in uterine leiomyomata.

  3. These results suggest that Substance P can retain the therapeutic effect of adipose-derived stem cells by elevating their proliferative and paracrine potential in ex vivo culture.

  4. Data suggest that endogenous tachykinin ligands for neurokinin-1 receptor exhibit large variations in binding/activation kinetics; substance P exhibits fast association kinetics; neurokinin A exhibits slow association kinetics.

  5. Mapping the co-localization of the circadian proteins PER2 (show PER2 Antibodies) and BMAL1 (show ARNTL Antibodies) with enkephalin and substance P throughout the rat forebrain has been reported.

  6. Circulating Neurokinin A >/= 50 ng/L is a strong indicator of poor prognosis when Neurokinin A remains above this concentration

  7. Substance P enhances tissue factor (show F3 Antibodies) release from granulocyte-macrophage colony-stimulating factor (show CSF2 Antibodies)-dependent macrophages via the p22phox (show CYBA Antibodies)/beta-arrestin 2 (show ARRB2 Antibodies)/Rho A (show RHOA Antibodies) signaling pathway.

  8. Decrease of mGluR5 (show GRM5 Antibodies) receptor density goes parallel with changes in enkephalin and substance P immunoreactivity in Huntington's disease

  9. Report absence of full-length neurokinin-1 receptor protein expression by cutaneous T cells in mycosis fungoides and discuss substance P signaling.

  10. Substance P was significantly increased in hypertrophic scars compared with matched unburned skin. In the reticular dermis and papillary dermis, SP represented significant correlation with pain.

Cow (Bovine) Tachykinin, Precursor 1 (TAC1) interaction partners

  1. Substance P alters the cytokine and chemokine (show CCL1 Antibodies) expression pattern in monocytes and blood-monocyte-derived macrophages.

Rabbit Tachykinin, Precursor 1 (TAC1) interaction partners

  1. There is an increase in the sensitivity of rapidly adapting receptor (RAR (show RAB40B Antibodies)) activity to substance P (SP) during high altitude exposure.

  2. Increased substance P-production precedes tendinosis, since tendinosis-like changes occur only after a minimum of 3 weeks of exercise

Tachykinin, Precursor 1 (TAC1) Antigen Profile

Protein Summary

This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TAC1

  • tachykinin, precursor 1 (TAC1) antibody
  • protachykinin-1 (tkn1) antibody
  • tachykinin 1 (Tac1) antibody
  • tachykinin 2 (Tac2) antibody
  • tachykinin, precursor 1 (Tac1) antibody
  • 4930528L02Rik antibody
  • beta-PPT-A antibody
  • Hs.2563 antibody
  • NK-1 antibody
  • NK1 antibody
  • NK2 antibody
  • NKNA antibody
  • NPK antibody
  • PPT antibody
  • PPT-A antibody
  • Ppt5fl antibody
  • PPTA antibody
  • PPTA3 antibody
  • RATPPTA3 antibody
  • SP antibody
  • TAC antibody
  • TAC1 antibody
  • TAC2 antibody
  • Tac3 antibody

Protein level used designations for TAC1

tachykinin, precursor 1 , tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma) , protachykinin-1 , tachykinin 1 , preprotachykinin , PPT , neurokinin 1 , neurokinin A , preprotachykinin A , substance P , delta preprotachykinin I , PPT-B , neurokinin 2 , neurokinin B-like protein Zneurok1 , neurokinin alpha , neuromedin L , neuropeptide K , preprotachykinin-B , substance K , tachykinin-3 , neuropeptide gamma , tachykinin 2 , protachykinin-1 preproprotein , Tachykinin (substance P, neurokinin A, neuropeptide K, neuropeptide gamma) , preprotachykinin I , substance P, neuropeptide gamma, neurokinin A

475239 Canis lupus familiaris
697350 Macaca mulatta
100034669 Ovis aries
100528498 Ictalurus punctatus
21333 Mus musculus
100379583 Cavia porcellus
21334 Mus musculus
6863 Homo sapiens
281512 Bos taurus
24806 Rattus norvegicus
100009275 Oryctolagus cuniculus
420573 Gallus gallus
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